Browse 191 real Biomedical and Health Sciences projects entered in 2025, with abstracts, awards and links to the original entries.
ISEF · 2025
Translational Medical Science Third Award
Neurodegenerative disorders like Alzheimer’s disease affect approximately 55 million people worldwide and are expected to double every 20 years. Standard detection methods, such as cerebrosp…
ISEF · 2025
Translational Medical Science
Sudden cardiac arrest (SCA) remains a significant health concern, accounting for over 436,000 deaths annually in the United States. An electrocardiogram (EKG) signal can help to identify ris…
ISEF · 2025
Translational Medical Science
In the last decade, the world has plunged into an opioid epidemic, with overdose deaths surging, amplified by the rise of synthetic drugs. In 2019, opioids accounted for 80% of global drug-r…
ISEF · 2025
Biomedical and Health Sciences
This project introduces a low-cost, portable diagnostic device for the rapid and accurate detection of pandemic-causing diseases. During the COVID-19 pandemic, millions of people lacked acce…
ISEF · 2025
Translational Medical Science
Coagulopathy defined as abnormal blood coagulation can cause thrombosis (hypercoagulation) or hemorrhage (hypocoagulation) leading to death. Current assays that provide a complete assessment…
ISEF · 2025
Biomedical and Health Sciences
In 2023, the Brazilian Amazon had the worst drought in history. People from the rural and indigenous areas suffered from many problems, especially hunger. In search of a food alternative fro…
ISEF · 2025
Translational Medical Science
Artificial Intelligence (AI) models like Convolutional Neural Networks (CNNs) are becoming powerful tools in medical imaging, but their “black box” nature limits clinical use. Doctors need t…
ISEF · 2025
Translational Medical Science
In recent years, research has demonstrated that the gut microbiome has an important role in normal brain function. This opens up possibilities for novel treatments of Alzheimer's, which affe…
ISEF · 2025
Translational Medical Science Third Award
Brain tumors affect thousands annually, with approximately 95,000 primary brain tumor cases diagnosed each year in the U.S. Diagnostic imaging errors affect an estimated 40 million patients…
ISEF · 2025
Translational Medical Science Fourth Award
The prevalence of diseases such as diabetic retinopathy (DR), glaucoma, and age-related macular degeneration (AMD) is rapidly increasing worldwide, with over 700 million people expected to f…
ISEF · 2025
Biomedical and Health Sciences
This project is a continuation of last year. The changes made include new testing and new cast designs. This year compression testing was done on the casts. To test this a force plate was us…
ISEF · 2025
Biomedical and Health Sciences Third Award
Posterior capsule opacification (PCO) is a major complication of cataract surgery, driven by the epithelial-to-mesenchymal transition (EMT). In this study, I investigated the mechanistic eff…
ISEF · 2025
Translational Medical Science
The Social Vulnerability Index (SVI) measures health vulnerability through a composite score from 0-1 based on four subcategories: socioeconomic status, household characteristics, housing ty…
ISEF · 2025
Translational Medical Science
Brain tumors represent a critical health challenge, affecting thousands of individuals annually and often leading to significant harm and mortality. Such challenges highlight the need for in…
ISEF · 2025
Biomedical and Health Sciences
Escherichia coli (E. coli) is one of the primary bacterial causes of urinary tract infections (UTIs), accounting for 75–95% of cases. Conventional antibiotics are commonly used for treatment…
ISEF · 2025
Translational Medical Science
Major Depressive Disorder negatively affects millions worldwide by decreasing productivity, degrading physical well-being, and increasing the risk of suicide by 60%. Moreover, miscalculating…
ISEF · 2025
Translational Medical Science
Cancer remains a leading cause of death worldwide, with approximately 10 million fatalities annually. Whole Slide Imaging (WSI) and Deep Learning can enhance histopathological analysis, enab…
ISEF · 2025
Translational Medical Science Second Award
Alzheimer's disease (AD) remains difficult to diagnose in its early stages. Current diagnostic approaches often miss subtle early symptoms, delaying intervention. In this research, a novel m…
ISEF · 2025
Biomedical and Health Sciences
Anthropogenic open burning is known to release hazardous chemicals and has been associated with an increased prevalence of cardiopulmonary issues. For example, studies show that veterans who…
ISEF · 2025
Translational Medical Science
Hospital infection is a serious current problem, affecting patients and generating high costs for public healthcare. One solution would be sustainable and natural alternatives. In this way,…
ISEF · 2025
Biomedical and Health Sciences
This study aimed to evaluate the effectiveness of various anti-plaque toothpaste formulations in reducing plaque, with a particular focus on comparing whitening and non-whitening products. P…
ISEF · 2025
Biomedical and Health Sciences
Globally, over 18% of men and 20% of women have been diagnosed with obesity as of 2025. While approved artificial sweeteners like aspartame, sucralose, acesulfame K, and saccharin are common…
ISEF · 2025
Translational Medical Science
Cancers arise from mutations in genes regulating cell growth, with the p53 tumor suppressor gene being mutated in over 50% of cases. The p53 protein activates genes that block cell prolifera…
ISEF · 2025
Biomedical and Health Sciences Second Award
Each year, over 10,000,000 people lose their lives to cancer. Many current cancer therapies cause deleterious side effects for patients and have an inordinate cost, ultimately leading to pat…
ISEF · 2025
Translational Medical Science
Study Objective: The primary aim of this study was to investigate how P2X1 receptor activation in lung adenocarcinoma (LA) influences the tumor microenvironment, particularly in promoting pr…
ISEF · 2025
Biomedical and Health Sciences
Asymptomatic intracranial hemorrhage (aICH) patients present with either a decrease or no change in NIHSS scores, which may falsely indicate clinical improvement in the days leading up to th…
ISEF · 2025
Translational Medical Science
Osteosarcoma (OS) is an aggressive bone cancer with poor survival rates due to chemoresistance. Chemotherapy, the main treatment, often fails as OS cells become resistant, leading to tumor g…
ISEF · 2025
Translational Medical Science
One of the most common complications of chemotherapy treatment is febrile neutropenia (FN), affecting 50% of patients with a mortality rate as high as 21%. Oftentimes, fever is the first and…
AJAS · 2025
Biomedical and Health Sciences (inferred)
Cardiac arrhythmias represent a significant global health challenge, affecting millions annually and frequently leading to misdiagnosis and inappropriate treatment. Consequently, 75% of arrh…
AJAS · 2025
Biomedical and Health Sciences (inferred)
Diabetic retinopathy (DR) is a microvascular eye condition that can lead to vision loss and blindness in individuals with diabetes. DR has been on the rise over the past 30 years and is the…