Browse real student projects, abstracts, and awards.
ISEF · 2023
Translational Medical Science Fourth Award
Renal Cell Carcinoma (RCC) is the deadliest urological disease in the world, accounting for more than 200,000 deaths annually. Detection before metastasis can improve 5-year survival rates d…
ISEF · 2023
Translational Medical Science
Nowadays, liquid biopsies based on detecting cell-free DNA (cfDNA) by Real-Time PCR have gained momentum in cancer diagnosis owing to their painlessness to patients. However, detecting cance…
ISEF · 2023
Translational Medical Science
Epilepsy is characterized by recurrent seizures and is often treated with anti-seizure medications. However, 30% of patients are refractory to this approach and do not experience seizure fre…
ISEF · 2023
Translational Medical Science
Alzheimer's Disease is a brain disorder that slowly deteriorates a person's cognitive function, which controls their executive functions and processing speed. Amyloid-Beta plaques & Tau-Aggr…
ISEF · 2023
Translational Medical Science
This project was created to aid patients who have a potential risk of developing Alzheimer's disease and/or glioblastoma brain tumors due to genetic, environmental, and lifestyle factors. In…
ISEF · 2023
Translational Medical Science
Most drugs function by binding to a “target” receptor, activating or inhibiting the “target” signal transduction pathway, which, in ~50% of drug trials, fails to occur, leading to low effica…
ISEF · 2023
Biomedical and Health Sciences
Microplastics pose a significant threat to sustainability for all organisms as they bring toxic chemicals into the ecosystems. In this novel study, public mass spectrometry datasets were sta…
ISEF · 2023
Translational Medical Science Fourth Award
According to the CDC, approximately 37.3 million people have diabetes mellitus in the US. Diabetic Retinopathy (DR) is a microvascular eye complication associated with diabetes and is the le…
ISEF · 2023
Biomedical and Health Sciences
Recurrent exposure to antibiotics is a form of stress that renders the carcinogenic Helicobacter pylori highly resistant to antimicrobial therapy. To our knowledge, the effect of ozonated AK…
ISEF · 2023
Biomedical and Health Sciences Third Award
Interleukin-6 (IL-6) and Interleukin-8 (IL-8) are cytokines related to general immune function, but within Sickle Cell Anemia (SCA) patients, their overproduction tends to cause autoimmune r…
ISEF · 2023
Biomedical and Health Sciences
Retinitis Pigmentosa (RP) is a common inherited retinal degeneration disease that is caused by the deterioration of rod photoreceptors, a type of retinal cell, leading to vision loss. One me…
ISEF · 2023
Translational Medical Science
COVID-19 and its several strains caused millions of infections and deaths worldwide, making it vital to understand how the virus interacts with human cells. Determining binding site location…
ISEF · 2023
Translational Medical Science
There is currently no definitive screening method or test for Parkinson’s Disease (PD), the second most prevalent neurodegenerative disorder with over 10 million cases worldwide and 1 millio…
ISEF · 2023
Biomedical and Health Sciences
Squid ink–derived nanomelanin has recently demonstrated the radiation protective capacity on the spleen of gamma ray-irradiated mice and X-ray irradiated keratinocyte HaCaT. In this study, w…
ISEF · 2023
Translational Medical Science Second Award
Type I and Type II Diabetes are the number one cause of kidney failure, affecting 422 million people and being responsible for 1.5 million deaths worldwide. The leading upstream cause of dia…
ISEF · 2023
Biomedical and Health Sciences Third Award
As the second leading cause of death, cancer has negatively impacted the lives of millions across the globe both directly and indirectly. In this study, we propose targeting the CaSR (calciu…
ISEF · 2023
Biomedical and Health Sciences
Schizophrenia is a complex brain disorder that affects 1% of the population and is characterized by alterations in cognitive function, acquisition and expression of behaviors not seen in hea…
ISEF · 2023
Translational Medical Science
LED lights are found in most modern technology such as electronics, indoor and outdoor lighting, and novelty items. Because they are so common, they could be affecting our health. The focus…
ISEF · 2023
Translational Medical Science
Screening and early diagnosis is necessary to prevent the recurrence of urinary stones and reduce treatment costs. This study aimed to propose a simple and rapid colorimetric method for dete…
ISEF · 2023
Biomedical and Health Sciences
Potatoes have many health benefits such as providing many vitamins and minerals to the body. However, people that have to have a low potassium diet, such as the renal diet due to lower kidne…
ISEF · 2023
Biomedical and Health Sciences
This study aimed to investigate the role of microRNA (miRNA) variants in Attention Deficit-Hyperactivity Disorder (ADHD). ADHD is characterized by inattention, impulsivity, and sugar craving…
ISEF · 2023
Biomedical and Health Sciences
Malaria is a mosquito-borne disease that caused over 619,000 deaths in 2022, Plasmodium falciparum being the most lethal species which affects humans. Although the disease has affected human…
ISEF · 2023
Translational Medical Science
Among various subtypes of breast cancer, triple-negative breast cancer (TNBC) is well-known as aggressive cancer with frequent anticancer drug-resistance and easy metastasis. Nevertheless, t…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Prostate cancer is the second leading cause of death for American men. Sadly, Native Hawaiian men have the highest mortality rate from the disease. Mamaki, an endemic Hawaiian plant and a vi…
ISEF · 2023
Translational Medical Science
With respect to evaluating biopsies for cancer diagnosis, a pressing yet often sidelined issue is that of anatomical pathology errors. Due to the image-based nature of biopsy examinations an…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Along the pathogenesis of Mycobacterium Tuberculosis (MTB), hypoxia-induced dormancy is a process involving the oxygen-depleted environment encountered inside the lung granuloma, where bacil…
ISEF · 2023
Translational Medical Science
Anti-cancer peptides (ACPs), a class of small peptide molecules, have gained increasing attention in cancer research due to their ability to target and kill cancer cells selectively, sparing…
ISEF · 2023
Translational Medical Science
Artificial intelligence is becoming a more widely utilized technology in the healthcare industry to improve predictability and consistency (Science Daily). However, this powerful technology…
ISEF · 2023
Translational Medical Science Third Award
The Kirsten rat sarcoma viral (KRAS) gene is the most frequently mutated oncogene, responsible for many types of highly fatal cancers — notably, pancreatic, colorectal, and non-small cell lu…
ISEF · 2023
Translational Medical Science
In-cell click-formed proteolysis targeting chimera molecules (CLIPTACs) were developed to allow both the inhibition and ubiquitination (degradation) of mutated proteins causing various disea…