38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2026
Translational Medical Science
Alzheimer's disease (AD) impacts approximately 55 million people globally and is predicted to affect 139 million individuals by 2050. As most diagnoses occur after substantial neurodegenerat…
ISEF · 2026
Translational Medical Science
Purpose: Laryngeal squamous cell carcinoma (LSCC) causes over 100,000 deaths annually worldwide. While adjuvant radiotherapy after surgical resection can reduce the risk of recurrence and im…
ISEF · 2026
Biomedical and Health Sciences Fourth Award
Microplastics have been a growing problem within the biomedical and health fields. However, mechanistic links between dietary exposure, molecular interaction, physiological impact, and mitig…
ISEF · 2026
Biomedical and Health Sciences
Music reduces stress and improves health by affecting the autonomic nervous system, and transcriptomic studies show it increases alpha-synuclein (SNCA), which regulates neuronal activity. Al…
CWSF · 2026
Health & Wellness
For over 440,000 Canadians living with severe speech impairments caused by neuromuscular conditions, communication is reduced to waiting for someone to interpret a movement that may never be…
CWSF · 2026
Disease & Illness Bronze Medal
Proactive disease screening is vital for preventive care, yet common biomarker tests are invasive, wasteful, and indefinitely slow. Conversely, NephroSense proposes generalized breath analys…
ISEF · 2026
Biomedical and Health Sciences
Schizophrenia is a chronic neurodevelopmental disorder. In low-resource settings like Zimbabwe, stigma and limited psychiatric infrastructure delay diagnosis. This study investigated whether…
ISEF · 2026
Translational Medical Science
Alzheimer’s disease (AD) causes the gradual loss of neurons, which leads to memory and cognitive problems. Due to the inability to replace the lost neurons, current treatments cannot stop or…
ISEF · 2026
Translational Medical Science
Intracranial aneurysms (IAs) often rupture before detection, causing hemorrhagic stroke that is fatal in 50% of cases. Expensive ($800 - $8400) hospital-based diagnostic tests are conducted…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division) First Award
Alzheimer’s disease (AD) affects 1 in 9 Americans over age 65, yet 98% of clinical trials fail, reflecting a mismatch between cellular heterogeneity and coarse-grained patient-level single-t…
ISEF · 2026
Translational Medical Science
Schizophrenia is a chronic neurodevelopmental disorder affecting approximately 24 million people worldwide. Despite its severity, its biological mechanisms remain poorly understood, and curr…
ISEF · 2026
Translational Medical Science
Purpose: Neuroblastoma and glioblastoma are highly aggressive malignant neural tumors affecting pediatric and adult populations respectively. Both are associated with very poor prognoses des…
ISEF · 2026
Translational Medical Science
Alzheimer's disease (AD) is a progressive neurodegenerative disease that continues to be difficult to diagnose in early stages. Despite studies demonstrating that when caught early, cognitiv…
ISEF · 2026
Translational Medical Science
Stroke, the 2nd leading cause of death(>7M) and 3rd leading cause of disability (94M) worldwide, is a time-critical emergency. Rapid, accurate stroke detection and severity assessment during…
CWSF · 2026
Disease & Illness Silver Medal
Alzheimer's disease affects over 55 million people, projected to double by 2050. Current pharmaceutical treatments including Donepezil and Memantine primarily alleviate symptoms without addr…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Stroke and migraine with aura, which affect over 300 million people globally, present with similar visual symptoms requiring differentiation through costly neuroimaging that may not be avail…
CWSF · 2026
Disease & Illness Bronze Medal
Current diagnostic methods for neurodegenerative diseases often depend on expensive imaging or on symptoms that only appear in later stages. My project, NeuroSight, explores a more accessibl…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Multiple Sclerosis (MS) is a chronic autoimmune neurological disorder affecting 2.9 million people worldwide. For MS, an incurable disease, the prevention of progression (from RRMS to PPMS)…
ISEF · 2026
Translational Medical Science
Parkinson's Disease (PD) is a neurodegenerative disorder that impairs motor function, making early detection crucial for slowing disease progression and managing symptoms. However, current d…
CWSF · 2026
Health & Wellness Gold Medal
Needle injections can be painful because they deform the skin, especially when larger needles are needed to deliver viscous fluids. In this project, a patented needle design that requires 57…
CWSF · 2026
Disease & Illness Silver Medal
Celiac disease is an autoimmune disorder where gluten causes damage to the small intestine.¹ A gluten sensor could allow patients to check their food. Current sensors are best at detecting w…
ISEF · 2026
Translational Medical Science
Microalgae are unicellural organisms that are found both in marine and freshwater ecosystems, ranging from tropical water habitats to subpolar areas. They have recently gained attention due…
AJAS · 2026
Biomedical and Health Sciences (inferred)
Background: Radiation therapy is an integral part of treatment for patients with brain cancers. Radiation-induced brain injury (RIBI) occurs in over 50% of patients, causing cognitive and ph…
CWSF · 2026
Disease & Illness Gold Medal
Heart disease currently affects roughly 6 million Canadians, with emerging research indicating that up to one-third of individuals with underlying cardiometabolic conditions will develop myo…
ISEF · 2026
Biomedical and Health Sciences Fourth Award
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness, characterized by progressive optic nerve damage often without symptoms until significant vision loss occurs.…
ISEF · 2026
Translational Medical Science
Embryo selection for Frozen Embryo Transfer (FET) is routinely based on subjective parameters. In most modern In-Vitro Fertilization (IVF) labs a quantitative approach for embryo selection i…
CSEF · 2026
Medicine & Physiology (Senior Division)
The California wildfires of 2025 (Palisades and Eaton) were the second-worst recorded weather disasters, with potential severe health consequences. It is becoming clear that cardiac abnormal…
CSEF · 2026
Medicine & Physiology (Senior Division)
In the field of microvascular diagnostics, the most significant diseases are those that silently compromise systemic health by attacking the smallest vessels in the human body. Nailfold capi…
CWSF · 2026
Disease & Illness Silver Medal
Diagnosing and treating ocular diseases quickly and accurately is essential, as prolonged ocular disease not only affects patient morbidity, but can also lead to permanent eye damage. Curren…
AJAS · 2026
Biomedical and Health Sciences (inferred)
Ophthalmological diseases pose a significant public health challenge, with an estimated 93 million adults in the United States at high risk for serious vision loss. However, only half of the…