Translational Medical Science
Fourth Award
Piezo proteins have been identified as key components of mechanosensitive ion channels in humans and other mammals. These channels are in the early stages of characterization; their mechanis…
Biomedical and Health Sciences
Individuals affected by ASD are characterized be a marked different in the ability to communicate and form relationships. New technologies for communication and learning have been used to im…
Toxicology
First Award
Objectives/Goals Lymphatic filariasis (elephantiasis) is a Neglected Tropical Disease caused by the parasitic nematodes Wuchereria and Brugia. Over 120 million people worldwide are infected…
Translational Medical Science
Hematopoietic system is a complex example of the stem cell concept that provides good opportunities for proliferation and differentiation studies. True hematopoietic stem cell that is charac…
Translational Medical Science
Allergies are an important health issue in our community. We want to develop a drug to lower the effects of allergies by characterizing the IgE receptor in a mast cell. The mast cell is an i…
Translational Medical Science
Kava has been used by Pacific Islanders for years. The purpose of this project was to determine which of the Kava metabolites activate THP-1 macrophages to produce pro/anti-inflammatory cyto…
Translational Medical Science
The purpose of this experiment was to investigate the effects of neuroinflammation and microglial activity on the progression of Alzheimer’s and to develop therapeutics with RNA-Interference…
Translational Medical Science
Fourth Award
Atherosclerosis, a form of cardiovascular disease, accounts for 17.3 million deaths/year(Mozaffarian,2014). Characterized by plaque formation in arteries, it leads to myocardial infarctions…
Translational Medical Science
The overall goal of this research is to characterize the functional consequences of mutations in FGFR3 that have been identified in cancer. Fibroblast growth factor receptors (FGFR) belong t…
Biomedical and Health Sciences
In 2011, the number of people in the world that had mobility disabilities was 785 million. Individuals with hemiplegia and paraplegia encounter difficulty in performing their daily routines,…
Translational Medical Science
Third Award
This research created a novel system capable of targeting cells based only on their mRNA sequences that would, upon recognition of a predetermined, target, mRNA sequence in a particular cell…
Translational Medical Science
Second Award
The goal of the project was to identify effective targeted drugs for inhibiting Protein Glucose Transporter 1 (GLUT1). Findings would be a big step towards curing cancer. GLUT1 transports gl…
Toxicology
Second Award
Objectives/Goals Parkinson's Disease (PD) is characterized by the death of dopaminergic (DA) neurons. The hallmark of PD is toxic aggregates of a-synuclein (a-syn) that induce degeneration o…
Translational Medical Science
Fourth Award
Cancer cells metabolize some basic nutrients, such as glucose, differently than normal cells do. Recently, investigation on cancer metabolism has increased due to the discovery of new metabo…
Toxicology
Fourth Award
Objectives/Goals Caffeine and cisplatin's effects on NADH related energy production pathways within a breast cancer cell line. Methods/Materials Treated cells with different concentrations o…
Biomedical and Health Sciences
ADHD affects more than one in ten adolescents in the United States. Additionally, neuropeptide Y (NPY), a neurotransmitter that regulates stress and emotional behavior, is strongly associate…
Translational Medical Science
Polymers that form polymer-DNA complexes (polyplexes) have been established to be safer and more effective -without causing death to harmless cells- than Chemotherapy and viral-mediated tran…
Biomedical and Health Sciences
Fluid intelligence (gF) is the basis of innovation, problem solving, and leadership; yet, a consistent theory of the neurological basis of gF is elusive. This study posited a new hypothesis…
Translational Medical Science
Cancer has threatened the lives of individuals all over the globe. With the rise of this infamous disease, prevention techniques such as radiation therapy and chemotherapy have been introduc…
Translational Medical Science
Amyotrophic Lateral Sclerosis is a fatal neurodegenerative disease. This disease involves the degeneration of upper and lower motor neurons and leads to loss of skeletal muscle function, eve…
Translational Medical Science
Bacteria small ribonucleic acids (sRNAs) are important cell regulators. Bacterial cells naturally take up nucleic acids in order to better regulate functions. However, bacterial cells that a…
Translational Medical Science
Second Award
Preterm infants are at a high risk of developing diffuse white matter injury (DWMI) after chronic hypoxia. DWMI is a leading cause of permanent neurodevelopmental disabilities and has been l…
Translational Medical Science
Second Award
Sericin is a protein found in silk produced by the silkworm (Bombyx mori) that may be useful as a growth promoter in cultured animal cells. Existing extraction methods require thermal denatu…
Translational Medical Science
Sepsis is an overwhelming immune response to an infection that accounts for 20-30 million hospital cases per year. One of the major issues surrounding this syndrome is the muscle atrophy of…
Translational Medical Science
Third Award
Antinuclear Antibody (ANA) in Systemic Erythematosus Autoimmune Disease patients was assumed to be capable of binding and killing cancer cells. This project has been carried out to experimen…
Toxicology
Honorable_mention Award
Objectives/Goals The objective for this project is to see the affects of different test subjects, against the Varroa mites. Methods/Materials Powdered sugar, Oyster mushrooms, Shimeji Mushro…
Biomedical and Health Sciences
The Brazilian civil-military dictatorship (1964-1985) institutionalized the disappearance of individuals as a form of repression of social and political resistance. This resulted in the Clan…
Toxicology
Objectives/Goals The objective of this study is to determine if sodium lauryl sulfate is present in face washes and if it will cause behavior differences in c. elegans. Methods/Materials SLS…
Biomedical and Health Sciences
The purpose of this experiment is to determine if women with breast cancer are more likely to be supertasters than women who do not have breast cancer. The research hypothesis states that wo…
Translational Medical Science
Neuroblastoma is a highly lethal childhood cancer that derives from incorrectly differentiated stem-cell-like neural crest cells. Cell signaling appears to be crucial for neuroblastoma regul…