Browse real student projects, abstracts, and awards.
ISEF · 2024
Translational Medical Science
The neurodegenerative disease, Amyotrophic Lateral Sclerosis (ALS), is characterized by progressive motor neuron (MN) degeneration leading to muscular atrophy (Scaricamazza et al., 2021). Th…
ISEF · 2024
Biomedical and Health Sciences
Amyotrophic Lateral Sclerosis (ALS), also called Lou Gehrig’s Disease, is an extremely damaging neurodegenerative disorder that attacks the motor system, which gradually weakens and wastes m…
ISEF · 2024
Biomedical and Health Sciences First Award
Osteosarcoma (OS), a primary bone tumor, arises from an imbalance in the bone remodeling pathway which fosters metastasis. In healthy bones, the microenvironment supports balanced remodeling…
ISEF · 2024
Biomedical and Health Sciences
Pancreatic cancer is one of the deadliest diseases in the world. Cancer-associated fibroblasts (CAFs) are an important component of the tumor microenvironment (TME) and important immune-nega…
ISEF · 2024
Translational Medical Science
The usage of DNA methylation at CpG sites within the gene body has the potential to be used as an alternative to promoter methylation for identifying gene expression. In this study, we focus…
ISEF · 2024
Translational Medical Science Fourth Award
As populations around the world grow older and pandemics ravage global health, the burdens of age-related diseases, such as arthritis, heart disease, and cancer, are increasingly prevalent.…
ISEF · 2024
Biomedical and Health Sciences Third Award
Every 15 seconds, a person suffers a traumatic brain injury (TBI), a leading cause of mortality and lifelong disability worldwide. Despite its prevalence, effective therapeutic treatments ta…
ISEF · 2024
Translational Medical Science
Characterized as recalcitrant cancer, small cell lung cancer (SCLC) is a rare neuroendocrine-type lung cancer with growing resistance to immune checkpoint inhibitors, leading to rapid metast…
ISEF · 2024
Translational Medical Science
Most cancer biomarkers are specific to a cancer type(s). By focusing on the most frequently occurring gene mutations across different types of cancers, a multi-gene biomarker was identified…
ISEF · 2024
Biomedical and Health Sciences
Non-alcoholic fatty liver disease (NAFLD), has become a major health problem worldwide and is predicted to become the leading cause of liver transplantation in the United States. In vitro mo…
ISEF · 2024
Translational Medical Science
In many healthcare facilities, the possibility of bedsores forming are a common concern. The formation of bedsores, also called pressure wounds, concern healthcare workers as the deep tissue…
ISEF · 2024
Translational Medical Science
Leukemia is a blood cell cancer ranking 15th in worldwide cancer incidence and 10th in death. The gut microbiome and its metabolites, e.g., short-chain fatty acids like propionate, are thoug…
ISEF · 2024
Biomedical and Health Sciences
Although previous research has studied the subfields of cancer genomics and population genetics separately, they have rarely merged. This study combines the knowledge of mutational signature…
ISEF · 2024
Biomedical and Health Sciences Second Award
1 in 5 people develop cancer in their lifetime. Due to treatment inefficiency, cancer is the leading cause of death worldwide. Deciphering immune cell-cancer cell interactions within the tum…
ISEF · 2024
Translational Medical Science
Alzheimer's disease is a widespread neurodegenerative disorder characterized by abnormal protein accumulation in the brain. From 1990 to 2019, the global burden of Alzheimer's disease and ot…
ISEF · 2024
Translational Medical Science
Each year, cardiovascular disease(CVD) and cancer account for about 17,900,000 and 10,000,000 mortalities, respectively, worldwide. Both CVD and cancer involve invasive, costly, and dangerou…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Lung and ovarian cancers continue to be leading causes of cancer deaths in the United States, and refining the treatment of these cancers is needed to improve patient survival. The goal of t…
ISEF · 2024
Biomedical and Health Sciences Third Award
Introduction Ventilation (V) and perfusion (Q) remain the main physiologic correlates to assess respiratory gas exchange. Currently several modalities can be used to ascertain V/Q with inhal…
ISEF · 2024
Translational Medical Science
Alzheimer's Disease (AD) causes memory decline beyond normal aging and is the most common cause of dementia. Early detection and intervention can delay the progression of AD and alleviate sy…
ISEF · 2024
Biomedical and Health Sciences
Timely detection of brain tumors is vital in increasing a patient's chance of recovery. Magnetic resonance imaging (MRI) Segmentation is used to detect and diagnose brain tumors, traditional…
ISEF · 2024
Translational Medical Science
Globally, anthropogenic climate change is causing an increase in wildfires, resulting in increased exposure to wildfire smoke. Current literature indicates exposure to a single wildfire smok…
ISEF · 2024
Translational Medical Science
Oral mucositis is a common and debilitating side effect of cancer treatment occurring in 90% of head and neck cancer patients undergoing radiation, 40% of patients with solid tumours receivi…