Browse real student projects, abstracts, and awards.
ISEF · 2017
Translational Medical Science Third Award
BACKGROUND: Malaria is a disease that mainly affects the poor, and is caused by a parasite (plasmodium) that cannot reproduce outside of humans. Most malaria patients are asymptomatic until…
ISEF · 2017
Biomedical and Health Sciences
Parkinson’s disease (PD) occurs when dopaminergic neurons start to degenerate. It isn’t clear what happens to initiate PD, but it’s known that a mitochondrial respiratory chain dysfunction a…
ISEF · 2017
Biomedical and Health Sciences Fourth Award
Parkinson’s Disease (PD) is a locomotor disease characterized by toxic aggregation of the protein a-syn in neurons. In recent research, mice with a PD-causing mutation failed to exhibit dise…
ISEF · 2017
Biomedical and Health Sciences
Twelve percent of women develop invasive breast cancer (National Cancer Institute, 2012). Breast cancer is the second leading cause of cancer deaths in women in the United States, killing ov…
ISEF · 2017
Biomedical and Health Sciences
Rheumatoid arthritis (RA), the most common form of autoimmune arthritis, is a progressive inflammatory disease with unclear causes. Many people with arthritis feel worsening symptoms when we…
ISEF · 2017
Biomedical and Health Sciences
Lacrosse is one of the fastest growing sports in North America, and the physical nature of the sport puts players at risk of sustaining head injuries, including concussions. Concussions are…
ISEF · 2017
Biomedical and Health Sciences
Type 1 diabetes mellitus (T1D) results from the autoimmune destruction of pancreatic ß cells, leading patients to require lifelong insulin therapy. Transplantation of isolated pancreatic isl…
ISEF · 2017
Biomedical and Health Sciences
Prostate Cancer (PCa) is the most commonly diagnosed malignancy in North American men. PCa displays a broad range of clinical behavior from relatively benign to an aggressive metastatic dise…
ISEF · 2017
Translational Medical Science
Metastatic cancers are associated with a poor prognosis, as current treatments often prove ineffective at targeting every cancer cell and are rather damaging to normal cells. The research re…
ISEF · 2017
Translational Medical Science
Zika virus infection can cause fever, rash, conjunctivitis, and joint pain, which typically last up to 1 to 2 weeks, but can also lead to severe diseases such as Guillain-Barre syndrome (GBS…
ISEF · 2017
Translational Medical Science
Inflammation plays crucial roles in tumorigenesis. Cancer cells evade immune surveillance by recruiting myeloid-derived suppressor cells and T-regulatory cells, releasing inflammatory mediat…
ISEF · 2017
Translational Medical Science
Background: Donation after circulatory determination of death (DCD) could improve donor heart availability, which currently limits transplantation. However, reluctance to this approach arise…
ISEF · 2017
Biomedical and Health Sciences Third Award
Hepatocellular Carcinoma (HCC) is the second leading cause of cancer death worldwide, and cirrhosis underlies 80-90% of HCC. Cirrhosis is initiated and advanced due to the activation of hepa…
ISEF · 2017
Biomedical and Health Sciences Second Award
The goal of this study was to compare hospitalization outcomes in women with Turner Syndrome (TS), the condition of missing the second X chromosome, and non-TS women. It was hypothesized tha…
ISEF · 2017
Biomedical and Health Sciences Second Award
Introduction: Nasal breathing is the preferred method of respiration for a myriad of physiological reasons, one of which relates to Nitric Oxide (NO) production in the paranasal sinuses, bas…
ISEF · 2017
Biomedical and Health Sciences
Identifying remains is an essential practice needed to further investigations of missing persons, criminal activity, and forensic anthropology. Bones found in the field are subject to weathe…
ISEF · 2017
Biomedical and Health Sciences
Ultraviolet radiation (UVR) exposure is a health hazard that causes several diseases including cancer, neurodegenerative disease, XP syndrome, cataracts of the eye, and sunburn. The ozone la…
ISEF · 2017
Translational Medical Science Fourth Award
Using of addictive substances is one of humankind's oldest problems. They are considered an important disease of the brain. Substance abuse is not only the problem of health sciences, but al…
ISEF · 2017
Biomedical and Health Sciences Fourth Award
Prescription of chemotherapeutic anti-folate drugs is the frontline treatment for breast cancer patients to induce folate-deficit cancer cytotoxicity. Alongside, folate supplements are used…
ISEF · 2017
Translational Medical Science
The purpose of this study is to optimize conditions for antibody-dependent cell-mediated cytotoxicity (ADCC) by natural killer (NK) cells to lyse multiple myeloma (MM) cells. The incidence o…
ISEF · 2017
Biomedical and Health Sciences
Gymnasts (floor tumblers) experience a high number of injuries due to the vertical impact force of landing. Landing forces can range from 3.9 to 14.4 times the gymnast's body weight (Panzer,…
ISEF · 2017
Translational Medical Science
We survived 1322 fifteen to twenty-year-old students to learn how much they knew about their sleep and if they employed any sleep educing techniques. We found that 43,57% of students are uns…
ISEF · 2017
Translational Medical Science Third Award
Diabetic retinopathy (DR), the leading cause of blindness among working-age adults, is also leading cause of preventable blindness worldwide. Many patients, particularly in developing areas,…
ISEF · 2017
Biomedical and Health Sciences
Until the discovery of the CAL-1 cell line, blastic natural killer cell lymphoma (BNKCL), a highly fatal form of leukemia, was an insurmountable obstacle for oncologists. Even with CAL-1, cu…
ISEF · 2017
Translational Medical Science
Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor. Patients with GBM have a median survival of 15 months. Current treatments for GBM are quite limit…
ISEF · 2017
Biomedical and Health Sciences Fourth Award
According to WHO’s Global Database on Child Growth and Malnutrition nearly one third of children under 5 suffer irreversible damage to their physical and cognitive development due to severe…
ISEF · 2017
Translational Medical Science Fourth Award
Early diagnosis is of unequivocal importance to survive debilitating multiple organ failure (MOF), the leading cause of death in the intensive care unit (ICU). However, current lab-based met…
ISEF · 2017
Translational Medical Science Fourth Award
Small cell lung cancer (SCLC), the most fatal subtype of lung cancer, has a five-year survival rate of 2%. Currently, patients must get expensive computerized tomography and positron emissio…
ISEF · 2017
Translational Medical Science
This project takes a novel approach to breast cancer metabolomics to reveal biomarkers with the potential to be used in a breast cancer diagnostic test. This test, unlike current methods, wi…
ISEF · 2017
Translational Medical Science
With the increasing number of urbanized people working with shifts and dealing with heavy stresses, the effects of sleep-related problems are greatly amplified. Our project aims to use cheap…