Browse real student projects, abstracts, and awards.
ISEF · 2024
Translational Medical Science
Antibiotic resistance poses a global threat, leading to millions of infections annually and thousands of deaths and the chance of the world entering a post-antibiotic era where common infect…
ISEF · 2024
Translational Medical Science
Each year, nearly 2 million individuals in the United States alone receive a cancer diagnosis. Traditional methods for tracking tumor growth are inaccurate and invasive as MRI scans and biop…
ISEF · 2024
Biomedical and Health Sciences
PTPMT1 is a gene that codes for a mitochondrial phosphatase essential for mitochondrial function, making it crucial for the development of organisms. Several studies have shown a strong link…
ISEF · 2024
Biomedical and Health Sciences Second Award
Gout is the most prevalent inflammatory joint disease, affecting 2-4% of the global population. It causes disability, reduced quality of life, and increased mortality as well as tens of bill…
ISEF · 2024
Translational Medical Science Third Award
The MERS-CoV is a critical public health concern due to its infectious nature, severe symptoms and high fatality rate, with 36% of MERS-CoV cases resulting in death. This highlights the urge…
ISEF · 2024
Translational Medical Science
Every year, more people in the U.S are diagnosed with skin cancer than all other cancers combined. Early detection of these cancers can tremendously increase the 5-year survival rate. Curren…
ISEF · 2024
Translational Medical Science Third Award
Tauopathies are neurodegenerative disorders characterized by the deposition of abnormal tau in the brain. There are over 20 tauopathies that collectively affect millions of people around the…
ISEF · 2024
Translational Medical Science
Pancreatic cancer shows the highest mortality rate and, to date, no early detection devices are available. However, early detection could improve the survival rate. This study is conducted t…
ISEF · 2024
Translational Medical Science
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy characterized by the uncontrolled growth of abnormal B-cells in the lymphatic system. The activated B cell (ABC) subtype p…
ISEF · 2024
Biomedical and Health Sciences
Cataracts, the decomposition of crystallins found in the lens of the eye, are increasingly common among today's population of aging and diabetic patients. Photosensitive medications can incr…
ISEF · 2024
Biomedical and Health Sciences Second Award
High-grade serous ovarian cancer (HGSOC) remains the fifth leading cause of cancer death among women. It has recently been demonstrated that stimulator-of-interferon genes (STING) is highly…
ISEF · 2024
Biomedical and Health Sciences
Population aging increases the occurrence of chronic heart disease characterized by decrease of cardiomyocyte number and their contractility. The absence of natural heart self-repair mechani…
ISEF · 2024
Biomedical and Health Sciences
Our body has many ways to defend itself against foreign pathogens with the first defense being our innate immune system. Among the many different substances that can improve our immune syste…
ISEF · 2024
Biomedical and Health Sciences
Excessive placental secretion of neurokinin B (NKB) is implicated in pre-eclampsia, a disorder associated with maternal health complications. Hormone antagonists are substances that regulate…
ISEF · 2024
Translational Medical Science
The objective of this research project is to present the development of prototupes of a herbal tincture and its respective healing ointment, created from the rich compounds mentioned in the…
ISEF · 2024
Biomedical and Health Sciences
The second most common skin cancer, Squamous Cell Carcinoma, is a persistent problem that threatens the lives of thousands, yearly. Cellular reproduction is a factor allowing these cancerous…
ISEF · 2024
Biomedical and Health Sciences Third Award
Research Significance: Alzheimer's disease affects nearly 52 million individuals worldwide, with projections indicating a significant increase to 75 million by 2030 and a staggering 152 mill…
ISEF · 2024
Translational Medical Science
Typical cancer treatments like chemotherapy are not targeted treatments and kill healthy cells along with cancer cells, causing negative side effects. Targeted cancer treatments are a soluti…
ISEF · 2024
Biomedical and Health Sciences
A total of 20 hemp and CBD commercial products (4 vape oils, 7 oils, 4 edibles and 5 topicals) were collected from dispensaries and CBD shops. These products were extracted by solvent extrac…
ISEF · 2024
Translational Medical Science
As STEM programs become increasingly popular, the use of coin batteries has also increased. These batteries are used to demonstrate the wonders of electricity to children. However, they come…
ISEF · 2024
Biomedical and Health Sciences
The a-ketoglutarate dehydrogenase complex (KGDHC) enzyme – involved in the Krebs cycle – has been shown to have significantly decreased activity that is thus far unexplained in Alzheimer's d…
ISEF · 2024
Biomedical and Health Sciences
Cisplatin is a platinum based chemotherapy that has been used for over 40 years in cancer treatment. The purpose of this experiment is to examine how cisplatin treatment in breast cancer aff…
ISEF · 2024
Biomedical and Health Sciences
Amyloid-beta is a protein that can misfold into pathological fibril aggregations and lead to the formation of plaques in the brain—one of the hallmarks of Alzheimer’s disease (AD). While the…
ISEF · 2024
Translational Medical Science
Pancreatic Cancer has the lowest survival rates of all cancers due to much diagnosis occurring in the later stages. Methods such as chemotherapy and drug treatments are effective but can lea…
ISEF · 2024
Translational Medical Science
Atopic Dermatitis (AD) is a chronic skin disease which occurs due to many genetic and environmental factors.AD is a disease that can seriously affect the comfort of patients. The barrier pro…
ISEF · 2024
Biomedical and Health Sciences
Objectives The objective of my experiment was to test the effect different diets (high sugar or keto) have on neurodegenerative diseases by measuring basal slowing rate in C. elegans which h…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Breast cancer (BC) is the most frequently diagnosed disease among women, with 2.3 million new cases and 669,000 deaths identified in 2022 alone. Most studies on epigenetic diagnosis biomarke…
ISEF · 2024
Biomedical and Health Sciences
Obesity is a detrimental disease that causes individuals to suffer higher risks for developing cardiovascular diseases, diabetes, and cancer. Recently, a population study found that a loss o…
ISEF · 2024
Biomedical and Health Sciences
Around the world, men and women suffer from several types of breast cancer, among them being triple-negative breast cancer (TNBC). TNBC lacks targeted therapy; therefore, it's commonly treat…
ISEF · 2024
Biomedical and Health Sciences
In recent decades, infertility rates have risen globally, with 11% of women and 9% of men experiencing decreased fertility. Studies pertaining to male fertility are abundant, yet studies of…