Browse real student projects, abstracts, and awards.
ISEF · 2018
Translational Medical Science
Optical Coherence Tomography (OCT) is relatively new non-invasive imaging technique that can be used for a variety of medical diagnosis. OCT is cost-effective and requires fewer resources th…
ISEF · 2018
Translational Medical Science
Photodynamic therapy (PDT) is a form of cancer treatment that involves administering a photosensitizing drug and irradiating it with an external light source. Upon exposure, the photosensiti…
ISEF · 2018
Biomedical and Health Sciences
Hydrogen peroxide (H2O2) is crucial indicator of inflammatory diseases due to its extensive role in the inflammation process. However, despite its importance as a diagnostic indicator, there…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Neuroblastoma(NB) is a pediatric cancer present in children under the age of 16, responsible for a disproportionate 15% of all childhood cancer deaths worldwide. Traditionally cells differen…
ISEF · 2018
Translational Medical Science Fourth Award
Lipopolysaccharides (LPS) are harmful biomolecules found on the surface of gram-negative bacteria and are responsible for over 50% of cases of sepsis, the leading cause of death in US hospit…
ISEF · 2018
Translational Medical Science
Breast cancer is the most common diagnosed cancer in women worldwide. Despite the success of surgery to treat early stages of breast cancer, later stages often require systemic chemotherapy…
ISEF · 2018
Translational Medical Science Fourth Award
Purpose: Ebola virus (EBOV) can cause severe and fatal hemorrhagic fever in humans. Being capable of causing large-scale epidemics, EBOV also emerges as a global security threat. Therefore,…
ISEF · 2018
Translational Medical Science
Hypodiploid B-ALL is a high-risk form of acute leukemia with a dismal prognosis and an 8-year survival rate of only 37%. Because standard chemotherapy is largely ineffective, there is an urg…
ISEF · 2018
Translational Medical Science Third Award
Neurometabolic and vascular changes have been shown to pre-date amyloid deposition and cognitive impairment in Alzheimer’s disease by several decades. However, these changes are not well cha…
ISEF · 2018
Biomedical and Health Sciences
Diffuse Large B Cell Lymphoma (DLBCL) is the most common form of Non-Hodgkin’s Lymphoma. Current chemotherapy fails in approximately 50% of patients; consequently, understanding DLBCL pathog…
ISEF · 2018
Biomedical and Health Sciences
Mosquito borne diseases such as chikungunya, jaundice, malaria, and dengue are common in my country. Therefore, we have to be alert of its breeding grounds especially in our neighborhood. Th…
ISEF · 2018
Biomedical and Health Sciences
Chemotherapy, a major cancer treatment approach, suffers seriously from multidrug resistance (MDR), generally caused by innate DNA repair proteins or transmembrane efflux proteins that remov…
ISEF · 2018
Translational Medical Science First Award
Bruxism, the involuntary grinding and/or clenching of teeth, is a condition which often goes undiagnosed until irreversible damage occurs. Although research on this topic has been extensive,…
ISEF · 2018
Translational Medical Science
Cancer is one of the most prevalent diseases affecting humans today and its lack of early diagnosis is leading to many millions of deaths worldwide. Hypothesis, in order to help people scree…
ISEF · 2018
Biomedical and Health Sciences
Coeliacs are required to follow a strict gluten free diet, to prevent damage to the small intestine. This experiment investigated the efficacy of two gluten digestive dietary supplements in…
ISEF · 2018
Biomedical and Health Sciences
The purpose of this project was to determine the effect of yeast-derived beta-glucan stimulation on the cytokine production and tumoricidal effect of macrophages. It was hypothesized that be…
ISEF · 2018
Biomedical and Health Sciences
Derivatives of cobalamin (Vitamin B-12) are important to the function of enzymes required for metabolism. Failure to convert cobalamin into its derivative forms leads to build up of methylma…
ISEF · 2018
Translational Medical Science
Ovarian cancer affects countless women worldwide. Unfortunately, systemic chemotherapy for treatment of ovarian cancer necessitates one-time super dosing, leading to the onset of severe side…
ISEF · 2018
Translational Medical Science
Rambutan fruit is a local fruit that can be found abundantly in Malaysia. The skin of rambutan has been reported to possess few phyto-constituents that has anti-cancer properties. Hence, the…
ISEF · 2018
Translational Medical Science
Lung cancer is the second most common cancer and accounts for 1 in 4 cancer deaths. Sulindac is an FDA approved anti-inflammatory drug. Metformin is an anti-diabetes drug which is also FDA a…
ISEF · 2018
Translational Medical Science Third Award
Alzheimer’s disease (AD) is a neurodegenerative, fatal brain disease characterized by impairments in memory, language, reasoning, and cognition. Identifying AD in its earliest stages of Mild…
ISEF · 2018
Translational Medical Science
Convolutional Neural Networks (CNNs) are machine learning systems that can classify images. Applying CNNs to medical images for recognizing different types of skin lesions can ultimately cre…
ISEF · 2018
Biomedical and Health Sciences
Cardiovascular diseases are the leading cause of death in the world. Atherosclerosis, the buildup of plaque on artery walls, is the precursor to many cardiovascular diseases. Unfortunately,…
ISEF · 2018
Translational Medical Science Second Award
Development of a Drug-likeness Rule for Natural Products Saadh Ahmed Northview High School, Johns Creek , GA, USA In the field of drug discovery, the first steps are crucial to the overall s…
ISEF · 2018
Translational Medical Science
Powassan virus is a causative agent of tick-borne encephalopathy that has shown a 375% increase in the United States in the last five years alone. There is currently no cure for infection by…
ISEF · 2018
Translational Medical Science Fourth Award
Curcumin has gained prominence for its pharmacological and medicinal applications, including antioxidant and anticarcinogenic properties. However, its low oral-bioavailability and stability…
ISEF · 2018
Translational Medical Science
Diseases are diagnosed based on physical attributes that define the disease. Many diseases such as cancer rely on invasive methods such as biopsy for detection. Others are hard to detect ear…
ISEF · 2018
Biomedical and Health Sciences
The most common cause of Acute Myeloid Leukemia is the mutation of the NPM1 protein. Cells can only differentiate when NPM1 is in the nucleus because the protein NPM1 carries with it master…
ISEF · 2018
Biomedical and Health Sciences
The reason for this science fair project was to see if body mass index (BMI), stomach girth, and skinfold measurements indicated whether individuals are pre-disposed to diabetes. The hypothe…
ISEF · 2018
Biomedical and Health Sciences
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the human gastrointestinal tract with no known cure; periods of subsided inflammation are followed by periods of hyper…