Browse real student projects, abstracts, and awards.
ISEF · 2019
Translational Medical Science
Head and neck squamous cell carcinoma (HNSCC) comprises approximately 90% of all head and neck cancers and represents the sixth most common type of cancer worldwide. Surgery, radiotherapy an…
ISEF · 2019
Biomedical and Health Sciences
Purpose: There is in an estimated 7.9 million bone fractures annually in which 5-10% of these result in delayed healing and progression to chronic nonunions. One factor that has previously b…
ISEF · 2019
Translational Medical Science
Deregulation of the tumor suppressor p27kip1 results in the proliferation of common and aggressive cancers such as breast and prostate cancer. The purpose of this study is to investigate the…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Antibiotic resistance is a growing public health challenge which affects about two million people in the U.S. annually. The search for new antibacterial agents is focusing on small drug mole…
ISEF · 2019
Biomedical and Health Sciences
Ovarian germ cell tumors are tumors that arise from the egg cells of the ovaries. There are different types of ovarian germ cell tumors including mature and immature teratomas, metastatic tu…
ISEF · 2019
Translational Medical Science
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and is the third leading cause of cancer-related death worldwide. Over 90 percent of these cancer-related deaths are du…
ISEF · 2019
Translational Medical Science
Pneumonia emerges as the leading cause of death in children under five years of age worldwide, accounting for more than 1.6 million deaths each year in this age demographic. A combined 18% o…
ISEF · 2019
Biomedical and Health Sciences
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inheritable myocardial disease characterized by fibrofatty replacement of cardiomyocytes and is the leading cause of sudden cardi…
ISEF · 2019
Translational Medical Science
Piperlongumine (PLM) is a compound derived from the long pepper that can selectively kill cancer cells and cancer stem cells, which are often responsible for relapses. PLM has the potential…
ISEF · 2019
Translational Medical Science
Cardiovascular disease (CVD) is the leading cause of death worldwide, killing 17.9 million people annually and costing billions of dollars. The main cause of CVD is atherosclerosis, the buil…
ISEF · 2019
Biomedical and Health Sciences
Glioblastoma is a brain cancer that is resistant to treatment due to the migration of individual glioblastoma cells throughout the brain. This study measured the effect of NE-100, a sigma-1…
ISEF · 2019
Translational Medical Science
Angiostrongylus cantonensis (Rat Lungworm) is a parasitic nematode known to infect humans through ingestion of the third stage larvae and can cause inflammation and damage to the central ner…
ISEF · 2019
Translational Medical Science
Smart fine fiber scaffolds were developed to monitor and aid the healing process. Solutions of ECDA: 5,7 Eicosadiynoic acid (DA) with polyvinyl butyrate (PVB) were spun into fiber membranes…
ISEF · 2019
Translational Medical Science
Glaucoma and diabetic retinopathy are two of the leading causes of blindness in the United States today. Yet fifty percent of people with glaucoma are unaware that they have the condition an…
ISEF · 2019
Biomedical and Health Sciences
Chronic kidney disease (CKD) is increasingly recognized as a public health problem. It takes the sixth place in the causes of deaths in Egypt by 4%. The incidence rates of ESRD (end-stage re…
ISEF · 2019
Translational Medical Science Fourth Award
Cancer research is a priority for medicine and modern society. Melanoma is considered one of the most aggressive forms of cancer, since this tumor has aggressive behavior and it is metastati…
ISEF · 2019
Biomedical and Health Sciences
Infantile Hypertrophic Pyloric Stenosis (IHPS) is a condition that occurs in newborns from 0-6 months of age. Food is restricted from passing through the pylorus causing the obstruction of t…
ISEF · 2019
Biomedical and Health Sciences
OBJECTIVE: To investigate the mechanism by which flavanol (ZGM1,2-(2,3-dihydroxyphenyl)-5,7-dimethoxychroman-4-one) changes the aggregation process of beta-amyloid (Abeta) and verify the pro…
ISEF · 2019
Biomedical and Health Sciences
Alcohol and aspartame are commonly consumed substances. Alcohol, a depressant, is currently the most abused substance today. It slows down bodily functions and can severely damage the heart.…
ISEF · 2019
Biomedical and Health Sciences Third Award
Retinopathy of prematurity (ROP) is a retinal angiogenic disorder that results from rapid microvascular proliferation after exposure to oxygen supplementation in preterm infants. It is curre…
ISEF · 2019
Biomedical and Health Sciences
To provide broader protection and eliminate the need for the annual update of influenza vaccines due to mutations in the hemagglutinin (HA) and neuraminidase (NA) glycoproteins, biomolecular…
ISEF · 2019
Biomedical and Health Sciences Third Award
Background: Peanut allergies are an epidemic with no cure. Microbiome alterations favoring Bacteroides fragilis can dampen a peanut allergy. To clinically translate prior findings, a complex…
ISEF · 2019
Biomedical and Health Sciences
Age-related diseases are resulting in premature aging in humans, and it is reducing society’s quality of living. Studying genes related to premature aging will help further research to creat…
ISEF · 2019
Biomedical and Health Sciences
Muntingia calabura Linn (Tingiaceae), locally known as Aratiles or Jamaican cherry in its native neotropics, is widely distributed in the Philippines. Despite the various claims about its ph…
ISEF · 2019
Biomedical and Health Sciences
Huntington’s disease (HD) is a fatal, autosomal dominant, neurodegenerative disease that currently has no cure. Most neurodegeneration occurs in the striatum, which is comprised of 95% mediu…
ISEF · 2019
Biomedical and Health Sciences
Important biotechnological challenge is prolonged expansion of hematopoietic stem cells (HSC), without losses in their functional activity and high levels of proliferation. Cord blood is rec…
ISEF · 2019
Biomedical and Health Sciences
MicroRNAs (miRNAs) are short sequences of RNA (about 22 nucleotides) that are involved in the regulation of gene expression. My previous study has identified the serum miR-134 as a new bioma…
ISEF · 2019
Translational Medical Science
Diabetic retinopathy (DR) is the leading cause of preventable blindness in the world. Due to the necessity of expensive ophthalmoscopic equipment and a trained professional, the screening pr…
ISEF · 2019
Translational Medical Science
In traditional Nigerian medicine, different parts of Ficus exasperata Vahl, are used as analgesic, diuretic, wound healing, anti-parasitic and for treating hemorrhoids. However, much documen…
ISEF · 2019
Biomedical and Health Sciences
An aberrant interaction between wolframin and neuronal calcium sensor 1 (NCS1) explains the clinical implications of Wolfram Syndrome, an orphan disease without a cure. Wolfram Syndrome is a…