20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2020
Translational Medical Science
Diabetic retinopathy (DR) is a complication of diabetes that can lead to blindness and is the leading cause of blindness in working-age adults. DR will affect most type-1 diabetic (T1D) pati…
ISEF · 2020
Translational Medical Science
The drawback of chemotherapy for treating cancer is that the cancerous cells acquire drug resistance after constant exposure to the drug, making them impervious to further dose escalation. M…
ISEF · 2020
Biomedical and Health Sciences
Modern diagnosis of glioma tumors requires several MRI sequences of the brain, which can be costly, burdensome to the patient, and provide toxic risks due to the presence of metallic, often…
ISEF · 2020
Biomedical and Health Sciences
Sodium benzoate is one of the most commonly used preservatives in the food industry. Although the compound is recognized as safe by the FDA, the effects of sodium benzoate on human health ha…
ISEF · 2020
Biomedical and Health Sciences
Aspirin is an important drug in the medical field. It is used to relieve pain, reduce fever but also to prevent blood clots, lowering the risk of heart attack or stroke in people who had sur…
ISEF · 2020
Biomedical and Health Sciences
Cancer’s evasion of traditional therapies due to the constantly changing phenotype of cancer cells is becoming a major clinical problem and is responsible for 90% of cancer deaths worldwide.…
ISEF · 2020
Translational Medical Science
Planaria are well known for their phenomenal regeneration abilities. Because of the presence of totipotent stem cells (also known as neoblasts) throughout their body, they are commonly used…
ISEF · 2020
Translational Medical Science
Small-cell lung cancer (SCLC) is a highly aggressive form of lung cancer. Despite available chemotherapeutics, resistance develops rapidly, accounting for a 6%, 5-year survival rate. Strateg…
ISEF · 2020
Translational Medical Science
This study developed and characterized a novel proteolysis targeting chimera (PROTAC) incorporating a beta hairpin sequence motif. PROTACs facilitate the proteasomal degradation of ‘undrugga…
ISEF · 2020
Biomedical and Health Sciences
Immunotherapy is a treatment in which the body’s immune cells, are stimulated to fight diseases such as cancer. Several immunotherapies have been developed with the aim of helping T Cells ta…
ISEF · 2020
Biomedical and Health Sciences
Nanoparticles (NPs) are attractive cancer drugs but cannot target cancer cells, causing side effects in cancer therapy. To tackle this challenge, I developed NPs that could kill breast cance…
ISEF · 2020
Biomedical and Health Sciences
The research was aimed at testing the effects of the polyphenolic compound Epigallocatechin-3-gallate on three colorectal cancer cell lines. The effects of this substance have been observed…
ISEF · 2020
Biomedical and Health Sciences
This project studied the impact of tocopheryl acetate and diacetyl on the motility of Chlamydomonas reinhardtii as a model for EVALI (E-Cigarette and Vaping Associated Lung Injury). This is…
ISEF · 2020
Biomedical and Health Sciences
Turmeric and beta carotene, two antioxidants, have been known to have many benefits. Antioxidants prevent oxidation. This is a natural aging process that can damage cells and lead to disease…
ISEF · 2020
Biomedical and Health Sciences
Traumatic brain injuries (TBIs) are one of the most common issues found in the emergency room setting, with over 69 million people sustaining some form of TBI every year. Despite the million…
ISEF · 2020
Translational Medical Science
Quercetin, a flavonoid found in many fruits and vegetables, belongs to an extensive class of polyphenolic compounds. Previous studies reported that Quercetin inhibits the proliferation of va…
ISEF · 2020
Biomedical and Health Sciences
Cerebral brain ischemia is the third most common cause of death in developed countries. The neuronal death is the main cause of disruption of brain functions. Nowadays, it is impossible to t…
ISEF · 2020
Biomedical and Health Sciences
The purpose of the experiment is to test the effects Sulforaphane has on bacterial growth. If Sulforaphane causes ring of inhibition on a bacterial plate, then Sulforaphane does have an effe…
ISEF · 2020
Biomedical and Health Sciences
Immunotherapy has shown promise as a treatment approach for patients with hematologic malignancies by engineering one’s immune system to better target a particular antigen. Treatment for hem…
ISEF · 2020
Biomedical and Health Sciences
Parkour is the utilization of complex body movements -such as jumps, landings, and vaults- in an urban environment to move from one place to another as efficiently as possible. Much of the s…
ISEF · 2020
Translational Medical Science
Cardiac mesenchymal stem cells (CMCs) are novel and promising stem cells that have shown significant efficacy in improving heart function in rodents after myocardial infarction (MI) and may…
ISEF · 2020
Biomedical and Health Sciences
Current models of speech error monitoring, like the commonly used DIVA model, generally only account for articulation and phonology. They don’t account for semantic monitoring, or the meanin…
ISEF · 2020
Biomedical and Health Sciences
Cardiovascular disease (CVD) is the leading cause of death in the world, and the mature human heart has little capacity to regenerate. Recently, induced pluripotent stem cell-derived cardiom…
ISEF · 2020
Biomedical and Health Sciences
Aggregation of the protein alpha-synuclein causes symptoms of Parkinson’s Disease in human brains. Treatment of transgenic NL5901 C. elegans with the xenohormetic phytochemical curcumin was…
ISEF · 2020
Translational Medical Science
The long-term goal is to develop an automated, real time, in situ red blood cell (RBC) identification, counting, and RBC distribution width (RDW) calculating system using deep learning. The…
ISEF · 2020
Translational Medical Science
Dry macular degeneration affects nearly 200 million people worldwide. There is no FDA-approved therapy for this disease, which is the leading cause of irreversible blindness among people ove…
ISEF · 2020
Translational Medical Science
Stroke is the third leading cause of death in the United States, and this prevalent danger to the global population urges researchers to explore potential preventative measures. The three dr…
ISEF · 2020
Biomedical and Health Sciences
Acatalasemia, better known as the lack of the necessary amount of active catalase enzymes in the body, has been linked to diseases such as type 2 diabetes and colorectal cancer. This disease…
ISEF · 2020
Biomedical and Health Sciences
The purpose is to understand mechanisms associated with obesity and utilize natural or pharmaceutical anti-obesity medications on growth of nematodes. The hypothesis is anti-obesity medicati…
ISEF · 2020
Translational Medical Science
The primary focus of this research was to identify tuberculosis proteins recognized by guinea pig antibodies and their origin within the tuberculosis bacterium. Tuberculosis is one of the to…