38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2022
Translational Medical Science Second Award
Alzheimer's disease (AD) is characterized by toxic aggregates formed by amyloid beta (AB) and tau, which kill memory and learning neurons. With only symptomatic treatments for mild-moderate…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Patients suffering from this condition exhibit a neuroinflammatory response mediated by microglial cells; this response h…
ISEF · 2022
Translational Medical Science
There is an unprecedented global mental health and substance abuse crisis including prescription drugs, affecting adults and youth. A recent FDA guidance requires abuse liability testing in…
ISEF · 2022
Translational Medical Science
The hearts of humans as well as Daphnia magna are striated and neurogenic. In humans, substances that induce sleep also lower blood pressure and heart rate. Research indicates that when D. m…
ISEF · 2022
Biomedical and Health Sciences Second Award
Cardiovascular diseases are the most common cause of death in the world. Because humans form few cardiomyocytes post-birth, engineering new myocardium could transform the treatment of heart…
ISEF · 2022
Translational Medical Science Second Award
This study evaluated the cytotoxicity of two Centella asiatica (CA) methanolic leaf extracts on the metastatic, triple negative breast cancer (TNBC) cell line MDA-MB-231. CA is a plant regio…
ISEF · 2022
Biomedical and Health Sciences
Extracellular vesicles (EVs) also known as Exosomes which are secreted by cells and play functional role in cell-cell communications. Recent advances in EV field have shown that they can be…
ISEF · 2022
Biomedical and Health Sciences
My research investigated the medicinal properties of Lomatium dissectum (called “doza” in our Native language) and Sambucus caerulea (elderberry, “hubui”) under laboratory conditions. Would…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Microplastics in the air cause respiratory diseases and worsen the health of the population, thus a nose filter with a biodegradable membrane may reduce their adverse effects on the respirat…
ISEF · 2022
Translational Medical Science
Paracetamol is a widely used drug due to its analgesic and antipyretic properties, however, intramolecular bonding that occurs between the drug’s chemical groups make it susceptible to a hea…
ISEF · 2022
Biomedical and Health Sciences
Multiple Sclerosis (MS) is a debilitating neurological disease affecting the central nervous system and significantly impacting patients’ quality of life. The disease involves inflammation,…
ISEF · 2022
Translational Medical Science
Neurodegenerative diseases are among the top five causes of death worldwide, with one major cause of these diseases being high levels of oxidative stress. Nano-antioxidants are emerging nano…
ISEF · 2022
Biomedical and Health Sciences
Aortic aneurysms have increased in the past two decades because of the aging population and the rise in the number of smokers. Aortic aneurysms affect about 2.9 million people and is the 13t…
ISEF · 2022
Biomedical and Health Sciences
One may be surprised to learn that the same ingredient, luteolin, is in a huge scope of supplements. Luteolin is the primary ingredient in therapeutic, neuroprotective, anti-inflammatory, an…
ISEF · 2022
Translational Medical Science
Dementia-related Cognitive Impairment (CI) is a neurodegenerative disorder, affecting over 55 million people worldwide and growing rapidly at the rate of one new case every three seconds. Th…
ISEF · 2022
Translational Medical Science Fourth Award
Colorectal cancer (CRC) is responsible for 864,989 deaths annually, making it the second leading cause of cancer death worldwide. The leading upstream cause of cancer deaths is a lack of cli…
ISEF · 2022
Translational Medical Science Second Award
The current practice of treating cancer with radiation, chemotherapy, and immunotherapy is a one-size-fits-all approach, in which patients with the same type and stage of cancer receive the…
ISEF · 2022
Translational Medical Science
Multiple myeloma (MM), an incurable cancer of the plasma cells in the bone marrow, is the 2nd most common hematological malignancy. Melphalan is an alkylator chemotherapy and an effective tr…
ISEF · 2022
Translational Medical Science Third Award
PANDwriting is a novel screening system for neurodegenerative diseases (NDs), particularly targeted to increase Alzheimer's Disease (AD) and Parkinson's Disease (PD) diagnostic access in low…
ISEF · 2022
Biomedical and Health Sciences Second Award
Exosomes secreted by pediatric bone marrow mesenchymal stem cells (pBMSC-Exos) demonstrate optimal characteristics for bone tissue engineering. MSC-Exos of alternate origin have expedited bo…
ISEF · 2022
Biomedical and Health Sciences Third Award
Cardiovascular diseases (CVDs) have become the #1 cause of death; three-quarters of these deaths occur in lower-income communities. Electrocardiography (ECG), an electrical measurement captu…
ISEF · 2022
Biomedical and Health Sciences
Despite testing negative for SARS-CoV-2, numerous patients began reporting a broad spectrum of acute post-recovery medical symptoms (Post Acute Sequelae of SARS-CoV-2 (PASC)), which they wer…
ISEF · 2022
Translational Medical Science
PTSD is a neuropsychological disorder resulting from a traumatizing event. Given biases associated with self-assessment and diagnosis of PTSD, researchers are actively searching for unbiased…
AJAS · 2022
Medicine
Investigations indicate that diabetic patients with myocardial infarctions (MI) have an increased risk of acute kidney injury (AKI) post-MI. In diabetic MI, blood hemoglobin (Hb) rises, whic…
ISEF · 2022
Translational Medical Science
The COVID-19 pandemic had a major impact on mental health due to the increased stress caused by the mental toll of events of the pandemic and isolation from necessary preventative measures s…
ISEF · 2022
Biomedical and Health Sciences
In this research paper, the effect of age, gender, comorbidities and dexamethasone on the time until IgM and IgG antibodies appear in the bloodstreams of hospitalized patients, infected with…
ISEF · 2022
Translational Medical Science
Bromelain is a potentially useful enzyme derived from pineapple plants that may protect cells from sun exposure. We tested whether bromelain sourced from pineapple waste could protect cells…
ISEF · 2022
Biomedical and Health Sciences Third Award
Millions of people in the USA alone suffer from celiac disease or gluten intolerance. In previous work, I identified three fruit-derived enzymes that when combined have an efficient effect i…
AJAS · 2022
Medicine
To develop an alternative solution for Stress Urinary Incontinence (SUI) Stress urinary incontinence (SUI), is the leakage of urine by vigorous activities such as coughing and sneezing when…
ISEF · 2022
Translational Medical Science
Restricted arm force during activity is often required following bone disruption (iatrogenic or traumatic) to facilitate osteogenesis, but measuring patient force is challenging, especially…