Translational Medical Science
Retinal diseases such as glaucoma and diabetic retinopathy (DR) currently devastate the developing world, causing permanent visual impairment when left undiagnosed and untreated. Glaucoma is…
Translational Medical Science
I was fascinated by my community’s use of local plants for medicinal purposes. Elders in my community have used (and are still using) bush medicine whenever any of our people get sick. I wan…
Biomedical and Health Sciences
Non-small cell lung cancer (NSCLC) remains one of the most prominent causes of cancer-related deaths across populations despite advancing treatment options. NSCLC is typically treated with a…
Translational Medical Science
Photodynamic therapy (PDT) is successfully used in clinical oncology. This treatment uses photosensitizers and light of a specific wavelength. On the light, photosensitizers generate reactiv…
Biomedical and Health Sciences (inferred)
Potential roles for DGB25 adipose thermogenesis Jack Volpert1, Daniel Kramer2, Paul Cohen2 1 Riverdale Country School Bronx, NY 2Laboratory of Molecular Metabolism, Rockefeller University, N…
Biomedical and Health Sciences
Stabilizers such as gelatin is usually added to yogurt to improve the texture of the yogurt by increasing its viscosity and preventing syneresis. However, gelatins used in yogurt are derived…
Translational Medical Science
Radiology is the field of medicine concerned with the interpretation of imaging of the human body for disease diagnosis. Most major forms of medical imaging scans occur within one hour or le…
Translational Medical Science
Diabetic retinopathy (DR) is a complication of diabetes that can lead to blindness and is the leading cause of blindness in working-age adults. DR will affect most type-1 diabetic (T1D) pati…
Translational Medical Science
The drawback of chemotherapy for treating cancer is that the cancerous cells acquire drug resistance after constant exposure to the drug, making them impervious to further dose escalation. M…
Biomedical and Health Sciences
Modern diagnosis of glioma tumors requires several MRI sequences of the brain, which can be costly, burdensome to the patient, and provide toxic risks due to the presence of metallic, often…
Biomedical and Health Sciences (inferred)
Retinopathy of Prematurity (ROP), observed in premature infants with low birth weight, is a leading cause of blindness worldwide. ROP shows no external signs or symptoms. Normal blood vessel…
Biomedical and Health Sciences
Sodium benzoate is one of the most commonly used preservatives in the food industry. Although the compound is recognized as safe by the FDA, the effects of sodium benzoate on human health ha…
Biomedical and Health Sciences
Aspirin is an important drug in the medical field. It is used to relieve pain, reduce fever but also to prevent blood clots, lowering the risk of heart attack or stroke in people who had sur…
Biomedical and Health Sciences
Cancer’s evasion of traditional therapies due to the constantly changing phenotype of cancer cells is becoming a major clinical problem and is responsible for 90% of cancer deaths worldwide.…
Translational Medical Science
Planaria are well known for their phenomenal regeneration abilities. Because of the presence of totipotent stem cells (also known as neoblasts) throughout their body, they are commonly used…
Translational Medical Science
Small-cell lung cancer (SCLC) is a highly aggressive form of lung cancer. Despite available chemotherapeutics, resistance develops rapidly, accounting for a 6%, 5-year survival rate. Strateg…
Translational Medical Science
This study developed and characterized a novel proteolysis targeting chimera (PROTAC) incorporating a beta hairpin sequence motif. PROTACs facilitate the proteasomal degradation of ‘undrugga…
Biomedical and Health Sciences
Immunotherapy is a treatment in which the body’s immune cells, are stimulated to fight diseases such as cancer. Several immunotherapies have been developed with the aim of helping T Cells ta…
Biomedical and Health Sciences
Nanoparticles (NPs) are attractive cancer drugs but cannot target cancer cells, causing side effects in cancer therapy. To tackle this challenge, I developed NPs that could kill breast cance…
Biomedical and Health Sciences (inferred)
Grade IV glioblastoma is the most lethal and aggressive brain tumor in adults. Despite treatment advances combining maximal surgical resection with radiotherapy and concurrent adjuvant chemo…
Biomedical and Health Sciences
The research was aimed at testing the effects of the polyphenolic compound Epigallocatechin-3-gallate on three colorectal cancer cell lines. The effects of this substance have been observed…
Biomedical and Health Sciences
This project studied the impact of tocopheryl acetate and diacetyl on the motility of Chlamydomonas reinhardtii as a model for EVALI (E-Cigarette and Vaping Associated Lung Injury). This is…
Biomedical and Health Sciences
Turmeric and beta carotene, two antioxidants, have been known to have many benefits. Antioxidants prevent oxidation. This is a natural aging process that can damage cells and lead to disease…
Biomedical and Health Sciences
Traumatic brain injuries (TBIs) are one of the most common issues found in the emergency room setting, with over 69 million people sustaining some form of TBI every year. Despite the million…
Translational Medical Science
Quercetin, a flavonoid found in many fruits and vegetables, belongs to an extensive class of polyphenolic compounds. Previous studies reported that Quercetin inhibits the proliferation of va…
Biomedical and Health Sciences (inferred)
Diabetes is a disease that can require the hormone insulin to be prescribed as a treatment, resulting in inconvenience and possible deleterious conditions for patients due to the drug’s inje…
Biomedical and Health Sciences
Cerebral brain ischemia is the third most common cause of death in developed countries. The neuronal death is the main cause of disruption of brain functions. Nowadays, it is impossible to t…
Biomedical and Health Sciences (inferred)
Lifelong ingestion of glucose has been proven to significantly shorten lifespan in C. elegans, a worm with an evolutionarily conserved insulin signaling pathway, similar to that of humans. T…
Biomedical and Health Sciences (inferred)
The use of antidepressants during pregnancy is estimated at 15% of the pregnant population in the United States. The most widely-prescribed antidepressants for pregnant women are called sele…
Biomedical and Health Sciences
The purpose of the experiment is to test the effects Sulforaphane has on bacterial growth. If Sulforaphane causes ring of inhibition on a bacterial plate, then Sulforaphane does have an effe…