Browse real student projects, abstracts, and awards.
ISEF · 2020
Translational Medical Science
The purpose of this experiment is to identify the effects of different 2 Deoxy-D-glucose (2DG) concentrations on the proliferation of cancer cells. It was hypothesized that if a 2DG concentr…
ISEF · 2020
Biomedical and Health Sciences
Planarian, more specifically Brown planarian have an extremely high concentration of neoblast stem cells and causes the planarian to have some of the most reliable regeneration powers. This…
ISEF · 2020
Biomedical and Health Sciences
Obesity has reached epidemic proportions, becoming a preventable leading cause of death worldwide. A multitude of approaches and animal models have been employed to investigate the pathophys…
ISEF · 2020
Biomedical and Health Sciences
Surgical fires pose a major threat in the operating room (OR) to patients, personal, and to facility. Surgical Drapes served fuel for 85% of fires and 81% of fires involve electrocautery, wi…
ISEF · 2020
Translational Medical Science
A significant number of cases of Salmonellosis have been linked to the handling of the more than 50 million day old chicks sold annually from mail order hatcheries, suggesting the need for i…
ISEF · 2020
Biomedical and Health Sciences
Lupus Nephritis (LN) is an autoimmune disease that leads to chronic inflammation of the kidney and excessive proteinuria. Current methods of treatment involve management of symptoms and slow…
ISEF · 2020
Biomedical and Health Sciences
Traumatic brain injury (TBI) affects about 1.7 million individuals annually. It is one of the leading causes of death and disability in the U.S. The Klotho gene, which plays an important rol…
ISEF · 2020
Translational Medical Science
Breast cancer is the second leading cause of cancer mortality in women, contributing to roughly 40,000 deaths annually. While breast cancer can pose a threat to any woman, those with dense b…
ISEF · 2020
Translational Medical Science
Antibiotics are powerful medicines that fight certain infections and can save lives when used properly. However, with bacteria becoming more resistant to antibiotics, new methods to treat ba…
ISEF · 2020
Translational Medical Science
Experimentation was conducted to determine the presence of metabolic deviations as a result of nucleosome-remodeling factor (NURF) knockdown in combination with chemotherapies. Due to large…
ISEF · 2020
Biomedical and Health Sciences
Anxiety is the most common mental disorder in the United States, affecting some 40 million adults each year. During anxiety attacks, neurons release excessive amounts of adrenaline, causing…
ISEF · 2020
Translational Medical Science
Cancer has remained as one of the world's leading causes of death and although medical treatments exist, many of the current methods have cytotoxic effects to not only the cancer cells, but…
ISEF · 2020
Biomedical and Health Sciences
The survival rate for patients diagnosed with gliomas (the most common type of brain tumor) is 5.6%. Gliomas are primarily driven by pathways like NF-kB signaling, which plays a key role in…
ISEF · 2020
Biomedical and Health Sciences
Rheumatoid Arthritis is a debilitating autoimmune disease in which the body— a person’s immune system— attacks its own synovium. Rheumatoid arthritis results in heightened inflammatory respo…
ISEF · 2020
Translational Medical Science
Ivermectin, awarded the Nobel Peace Prize for Physiology or Medicine in 2015, was originally used as an anthelmintic. Ivermectin was invented by William Campbell and Satoshi Omura to treat p…
ISEF · 2020
Translational Medical Science
Research shows that mammograms can be 80-90 percent accurate in detecting breast cancer in women without dense tissue, however the accuracy of this metric drops drastically down to nearly 50…
ISEF · 2020
Translational Medical Science
Millions of people worldwide suffer from chronic pain with few treatments other than opioids available. Photobiomodulation (PBM) and electroacupuncture (EA) are two treatments for chronic pa…
ISEF · 2020
Biomedical and Health Sciences
Introduction: Children with mutations in mannose phosphate isomerase (MPI) develop early liver fibrosis that can progress to require liver transplantation. We have previously shown that MPI…
ISEF · 2020
Biomedical and Health Sciences
The K27M mutation in histone H3.3 drives incurable glioblastomas in children called Diffuse Intrinsic Pontine Gliomas (DIPG). Research in human cells shows that a deficiency in H3.3 protein…
ISEF · 2020
Biomedical and Health Sciences
Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, accounting for 31% of all deaths globally in 2016. This work will investigate the possibility of detecting CAD…
ISEF · 2020
Translational Medical Science
Hepatoblastoma is the most common liver tumor in children. Those with relapsed or metastatic disease continue to have a poor prognosis and require novel therapies to improve outcomes. PIM ki…
ISEF · 2020
Biomedical and Health Sciences
Right ventricular (RV) dysfunction is the main determinant of mortality in patients with pulmonary arterial hypertension (PAH); yet, there is limited information on the role of RV inflammati…
ISEF · 2020
Translational Medical Science
The aim of our work was to create an affordable and easy-to-use device for the early diagnosis of transparency disorders in the optical media of the human eye. As a result of the analysis of…
ISEF · 2020
Translational Medical Science
Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States because it’s five-year survival rate is 8.9%. This occurs because of late diagnosis which is affiliate…
ISEF · 2020
Translational Medical Science
Retinal diseases such as glaucoma and diabetic retinopathy (DR) currently devastate the developing world, causing permanent visual impairment when left undiagnosed and untreated. Glaucoma is…
ISEF · 2020
Translational Medical Science
I was fascinated by my community’s use of local plants for medicinal purposes. Elders in my community have used (and are still using) bush medicine whenever any of our people get sick. I wan…
ISEF · 2020
Biomedical and Health Sciences
Non-small cell lung cancer (NSCLC) remains one of the most prominent causes of cancer-related deaths across populations despite advancing treatment options. NSCLC is typically treated with a…
ISEF · 2020
Translational Medical Science
Photodynamic therapy (PDT) is successfully used in clinical oncology. This treatment uses photosensitizers and light of a specific wavelength. On the light, photosensitizers generate reactiv…
ISEF · 2020
Biomedical and Health Sciences
Stabilizers such as gelatin is usually added to yogurt to improve the texture of the yogurt by increasing its viscosity and preventing syneresis. However, gelatins used in yogurt are derived…
ISEF · 2020
Translational Medical Science
Radiology is the field of medicine concerned with the interpretation of imaging of the human body for disease diagnosis. Most major forms of medical imaging scans occur within one hour or le…