Browse real student projects, abstracts, and awards.
ISEF · 2020
Biomedical and Health Sciences
The tumor suppressor protein p53, also known as the “guardian of the genome,” is known for its various protective functions in the cell ranging from cell cycle regulation to apoptosis. The p…
ISEF · 2020
Biomedical and Health Sciences
Our project investigates one method of decellularization, and it’s effectiveness on spinach leaves. We aim to strip spinach leaves of their DNA, and leave only the extracellular matrix (EMC)…
ISEF · 2020
Translational Medical Science
Overexpression of HER2 is present in about 20-30% of breast cancer tumors. HER2 sends growth signals from the cell membrane to the nucleus and contributes to the accelerated proliferation of…
ISEF · 2020
Biomedical and Health Sciences
Triple negative breast cancer (TNBC) has a higher mitotic index compared to other types of breast cancer yet Ki-67 values are still being used, despite an unclear mechanism. Here we found th…
ISEF · 2020
Biomedical and Health Sciences
As industry processed food becomes increasingly detrimental to human health, studies indicate that the heart and associated cardiovascular tissues deteriorate more rapidly. A significant cor…
ISEF · 2020
Translational Medical Science
Danio rerio embryos have been identified to have over eighty-two percent of genes similar to mammals and have recently been used as models for human embryos. This investigation exposed Danio…
ISEF · 2020
Translational Medical Science
Objective: Alzheimer’s Disease (AD) is a neurodegenerative disease with confirmation only from post-mortem autopsy. This study was done to aid diagnosis for the expected 14-million future pa…
ISEF · 2020
Translational Medical Science
Dopamine is a neurotransmitter that is responsible for reward, pleasure, and many other functions in humans. Major Depressive Disorder (MDD) causes persistent psychiatric and physical sympto…
ISEF · 2020
Biomedical and Health Sciences
Lung cancer is the leading cause of cancer death worldwide. Diagnostic methods including CT-scans are expensive and time-consuming. miRNAs participate in gene-silencing, and can be dysregula…
ISEF · 2020
Biomedical and Health Sciences
Tissue engineering is a research field for regenerating damaged biological tissue by substituting human cells on an appropriate scaffolds, one of them collagen as a biodegradable polymer has…
ISEF · 2020
Translational Medical Science
Venous thromboembolism, comprising of deep vein thrombosis (DVT) and pulmonary embolism (PE), occurs approximately in 1 out of every 1000 American individuals. About two-thirds of episodes m…
ISEF · 2020
Translational Medical Science
Chemotherapy is currently a prominent medical intervention for cancer. However, studies have shown various nonspecific detrimental effects to healthy cells and tissues during treatment. In o…
ISEF · 2020
Biomedical and Health Sciences
Intensity-Modulated Radiation Therapy (IMRT) is a novel cancer treatment. Tomotherapy, a type of IMRT, is a patient specialized radiation treatment plan that is more precisely concentrated i…
ISEF · 2020
Biomedical and Health Sciences
The purpose of this study was to examine the effects of ear canal shape on the ability of sound transmission by providing data at a wide range of sound frequencies. The broad data generated…
ISEF · 2020
Translational Medical Science
With just 7% survival rates, Pancreatic Cancer continues to be one of the most lethal cancers in the world. In this cancer, significant upregulation of the polyamine called spermine, in the…
ISEF · 2020
Translational Medical Science
Less than 20% of patients’ Pancreatic Cancer (PC) is discovered before spreading to other organs, making it nearly impossible to surgically remove, and attributing to a 7% five-year survival…
ISEF · 2020
Biomedical and Health Sciences
Angiogenesis is the process of forming new blood vessels from pre-existing ones and is essential for many functions such as wound healing, embryonic development, and repair. However, angioge…
ISEF · 2020
Biomedical and Health Sciences
Helicobacter pylori is a gram-negative bacterium affecting above 50% of the world’s population, with higher prevalence in the developing world. It causes numerous gastrointestinal diseases s…
ISEF · 2020
Biomedical and Health Sciences
Gram-negative bacteria are associated with hospital-acquired infections. The infection control literature has identified that hospital sink drains can be a potential source of these hospital…
ISEF · 2020
Biomedical and Health Sciences
The purpose of this project was to see what specific influence exosomes have on MDA-MB-231 triple negative breast cancer cell characteristics of proliferation, migration and invasion. Exosom…
ISEF · 2020
Biomedical and Health Sciences
Although the number of US vaping related deaths is rising, the cause of death remains unidentified. Knowing the long term effects of non-nicotine vape aerosol components, vegetable glycerin…
ISEF · 2020
Translational Medical Science
The role of cannabidiol in a Caenorhabditis elegans epilepsy model was analyzed using adenosine and tumor necrosis factor alpha antagonists to further elucidate the protective effects of can…
ISEF · 2020
Biomedical and Health Sciences
Angiogenesis is responsible for the development of new blood vessels from previously existing vasculature. Anomalies of the growth and differentiation of these vessels result in vascular mal…
ISEF · 2020
Translational Medical Science
Vaping is a process of inhaling and exhaling an aerosol using some type of vaping device. Vaping has become very popular among people, especially teens. Propylene glycol (PG) and vegetable g…
ISEF · 2020
Biomedical and Health Sciences
Accurate flu forecasts are needed to limit the spread of outbreaks. Current flu forecasts have not incorporated several environmental, demographic, and transport factors. This study looks at…
ISEF · 2020
Translational Medical Science
Anemia is the most common blood disorder in the world, affecting more than 2 billion people. Iron deficiency anemia, in particular, affects more than 1 billion people across the globe with a…
ISEF · 2020
Translational Medical Science
Over the past year, approximately 10,000 American teens have died due to a prescription stimulant overdose. A comprehensive, accurate, and easily integrable approach to detect a drug overdos…
ISEF · 2020
Translational Medical Science
The hypothesis of the project was that machine learning can be used to identify disease patterns in medical imaging. Machine learning functions were used to identify patterns in chest X-rays…
ISEF · 2020
Translational Medical Science
Thousands of people are affected by ovarian cancer each year. Usually, ovarian cancer is not detected in the early stages. Typically, the cancer is detected when a tumor is already formed. T…
ISEF · 2020
Biomedical and Health Sciences
Colon cancer is a leading cause of death worldwide. Sea cucumbers are a potential source of medicinal compounds and have been consumed in traditional Chinese medicine. Thus, it was hypothesi…