Browse real student projects, abstracts, and awards.
ISEF · 2021
Biomedical and Health Sciences
How can the future be now? because we're already in the future, the future of stem cell therapy. This research targets the two retinal diseases retinitis pigmentosa and age-related macular d…
ISEF · 2020
Biomedical and Health Sciences
Although mental illnesses account for 30% of all medical disabilities, the mechanisms behind these disorders are still very poorly understood. A significant spectrum within neurodevelopmenta…
ISEF · 2020
Translational Medical Science
News reports of car injuries and sports concussions have shed light on a new "silent pandemic" for the current era: Traumatic Brain Injury (TBI). TBI induces a cascade pathway within neural…
ISEF · 2020
Translational Medical Science
The American Cancer Society projects that over 135,000 Americans will die from lung cancer in 2020. It is recognized that the earlier lung cancer is detected, the higher the survival rate an…
ISEF · 2020
Translational Medical Science
Atrial Fibrillation (AF) is a cardiac disease affecting over three million Americans with a prevalence of 1% (above 6% in the elderly). AF is an irregular heartbeat that can lead to blood cl…
ISEF · 2020
Biomedical and Health Sciences
This study seeks to answer the question of the significance of Diabetes Mellitus and categorical obese BMI as risk factors for the development of dementia, particularly Alzheimer’s disease a…
ISEF · 2020
Biomedical and Health Sciences
Colorectal cancer is the third most common cancer. Starting as polyps of abnormal growth in the epithelium, cancerous tissue can rapidly grow, invade surrounding tissue, reach the cardiovasc…
ISEF · 2020
Biomedical and Health Sciences
Extracellular vesicles (EVs) are nano-sized particles involved in intercellular signaling thought to be secreted by all cells. Differences in surface glycosylation of EVs have been observed…
ISEF · 2020
Translational Medical Science
The opioid crisis is a deeply rooted issue in our society today that must be addressed. 75% of people who began abusing opioids in the 2000s started with prescription drugs. To address this,…
ISEF · 2020
Biomedical and Health Sciences
Type 1 diabetes (T1D) is an auto immune disease driven by auto antibodies that target insulin producing beta cells in the pancreas. Currently there are no prevention methods for T1D. However…
ISEF · 2020
Biomedical and Health Sciences
Prescription opioid addiction is a national health crisis. Today, patients or physicians do not have a way of diagnosing if a painkiller given for relief is causing addiction. Current approa…
ISEF · 2020
Translational Medical Science
Background: Neoadjuvant chemotherapy (NAC) is often used as treatment for mid to late stage breast cancer prior to surgery. However, it is currently not possible to determine accurately or r…
ISEF · 2020
Biomedical and Health Sciences
Cancer biomarkers are measurable variables indicative of disease presence or progression. However, inadequate methods of biomarker identification combined with the underlying complexity of c…
ISEF · 2020
Biomedical and Health Sciences
With a dismal five-year survival rate of 8%, pancreatic cancer remains one of the most lethal epithelial cancers. A growing body of evidence suggests that deformities in cell-cell junctions…
ISEF · 2020
Translational Medical Science
Parkinson's disease is a neurodegenerative disorder that eventually deprives an individual of normal movement, affecting over ten million people worldwide. As it progresses, the person with…
ISEF · 2020
Translational Medical Science
Heart diseases are the number one cause of deaths globally, with three-quarters occurring in developing countries (WHO). In India, heart-related mortality rates in rural areas have surpassed…
ISEF · 2020
Biomedical and Health Sciences
Drug delivery devices specifically transport drugs to help reduce drug toxicity to healthy cells and repetitive drug administrations. This study analyzes the use of pH-responsive nanogels, p…
ISEF · 2020
Biomedical and Health Sciences
Gut epithelium turns over rapidly due to damage from digestion and toxins produced by the enteric microbiota. The rapid turnover process of gut epithelium is tightly regulated. Dysfunction o…
ISEF · 2020
Translational Medical Science
Beta-secretase (BACE), an enzyme responsible for the endoproteolysis of amyloid precursor protein to produce the hallmark amyloid-beta plaques of Alzheimer's pathology, has been of considera…
ISEF · 2020
Translational Medical Science
Currently, there is no fully reliable or accurate way to determine whether an individual has Parkinson’s disease. Moreover, 90% of clinically-confirmed Parkinson’s disease cases are idiopath…
ISEF · 2020
Biomedical and Health Sciences
Arsenic is a known carcinogen, which can be ingested through contaminated drinking water. Most studies in the high-level arsenic range have found a significant correlation between arsenic in…
ISEF · 2020
Translational Medical Science
Cognitive deterioration caused by Mild Cognitive Impairment (MCI), which is often a transition between regular aging and neurodegenerative disease (Alzheimer’s disease), is displayed before…
ISEF · 2020
Translational Medical Science
When skin cancer metastasizes the survival rate drops to 23%, so targeting skin cancer before this happens is paramount. E4orf4 is a gene that allows viruses to regulate gene expression, in…
ISEF · 2020
Biomedical and Health Sciences
Alzheimer’s disease (AD), the most common form of senile dementia, is one of the leading causes of death in the U.S. A predisposition or expression of chronic stress-related symptoms has bee…
ISEF · 2020
Biomedical and Health Sciences
Autoimmune diseases, including Rheumatoid Arthritis and Systemic Lupus Erythematosus, are characterized by symptoms of chronic tissue swelling and inflammation. It remains largely unknown wh…
ISEF · 2020
Translational Medical Science
Currently, there is a growing demand for organ transplants and an inability to meet such demand. Policies put in place by the United Network for Organ Sharing, or UNOS, restrict the acceptan…
ISEF · 2020
Translational Medical Science
Approximately every 3 minutes one person in the United States is diagnosed with a blood cancer. Leukemia is the most common cancer in children and teens, accounting for more than 3,500 cases…
ISEF · 2020
Translational Medical Science
Although Parkinson’s Disease (PD) is the fastest-growing leading cause of disability, 25% of patients are either misdiagnosed or diagnosed after severe neurodegeneration has already occurred…
ISEF · 2020
Biomedical and Health Sciences
Epilepsy is a terrible disease characterized by spontaneous recurrent seizures that negatively impact the day to day lives of affected patients. In addition to seizures, epilepsy patients al…
ISEF · 2020
Biomedical and Health Sciences
Familial Alzheimer’s Disease (FAD) is a hereditary neurodegenerative disease in which patients experience neurodegeneration and symptoms such as worsened memory, trouble learning, and motor…