Translational Medical Science
Fourth Award
Colorectal cancer (CRC) is responsible for 864,989 deaths annually, making it the second leading cause of cancer death worldwide. The leading upstream cause of cancer deaths is a lack of cli…
Translational Medical Science
Second Award
The current practice of treating cancer with radiation, chemotherapy, and immunotherapy is a one-size-fits-all approach, in which patients with the same type and stage of cancer receive the…
Translational Medical Science
Multiple myeloma (MM), an incurable cancer of the plasma cells in the bone marrow, is the 2nd most common hematological malignancy. Melphalan is an alkylator chemotherapy and an effective tr…
Translational Medical Science
Third Award
PANDwriting is a novel screening system for neurodegenerative diseases (NDs), particularly targeted to increase Alzheimer's Disease (AD) and Parkinson's Disease (PD) diagnostic access in low…
Biomedical and Health Sciences
Second Award
Exosomes secreted by pediatric bone marrow mesenchymal stem cells (pBMSC-Exos) demonstrate optimal characteristics for bone tissue engineering. MSC-Exos of alternate origin have expedited bo…
Biomedical and Health Sciences
Third Award
Cardiovascular diseases (CVDs) have become the #1 cause of death; three-quarters of these deaths occur in lower-income communities. Electrocardiography (ECG), an electrical measurement captu…
Biomedical and Health Sciences
Despite testing negative for SARS-CoV-2, numerous patients began reporting a broad spectrum of acute post-recovery medical symptoms (Post Acute Sequelae of SARS-CoV-2 (PASC)), which they wer…
Translational Medical Science
PTSD is a neuropsychological disorder resulting from a traumatizing event. Given biases associated with self-assessment and diagnosis of PTSD, researchers are actively searching for unbiased…
AJAS · 2022
Medicine
Investigations indicate that diabetic patients with myocardial infarctions (MI) have an increased risk of acute kidney injury (AKI) post-MI. In diabetic MI, blood hemoglobin (Hb) rises, whic…
Translational Medical Science
The COVID-19 pandemic had a major impact on mental health due to the increased stress caused by the mental toll of events of the pandemic and isolation from necessary preventative measures s…
Biomedical and Health Sciences
In this research paper, the effect of age, gender, comorbidities and dexamethasone on the time until IgM and IgG antibodies appear in the bloodstreams of hospitalized patients, infected with…
Translational Medical Science
Bromelain is a potentially useful enzyme derived from pineapple plants that may protect cells from sun exposure. We tested whether bromelain sourced from pineapple waste could protect cells…
Biomedical and Health Sciences
Third Award
Millions of people in the USA alone suffer from celiac disease or gluten intolerance. In previous work, I identified three fruit-derived enzymes that when combined have an efficient effect i…
AJAS · 2022
Medicine
To develop an alternative solution for Stress Urinary Incontinence (SUI) Stress urinary incontinence (SUI), is the leakage of urine by vigorous activities such as coughing and sneezing when…
Translational Medical Science
Restricted arm force during activity is often required following bone disruption (iatrogenic or traumatic) to facilitate osteogenesis, but measuring patient force is challenging, especially…
Translational Medical Science
The results of this project could enable real-time targeted transcranial magnetic stimulation (TMS) to become a clinical reality, improving outcomes for patients with depression, schizophren…
Biomedical and Health Sciences
Cardiovascular disease and cognitive impairment are among the biggest healthcare challenges facing the elderly. Integrity of the blood brain barrier (BBB) and lining of the blood vessels req…
Biomedical and Health Sciences
Second Award
Existing drugs are being researched for novel repurposed usages to supplant the traditional, inefficient process of new drug discovery. Cephalexin is a cephalosporin antibiotic purported to…
AJAS · 2022
Medicine
The atrophic form of age-related macular degeneration (dry AMD) affects nearly 200 million people worldwide. There is no Food and Drug Administration (FDA)-approved therapy for this disease,…
Biomedical and Health Sciences
Third Award
Despite advancements in modern medicine, malaria continues to have high morbidity and mortality, particularly in Sub-Saharan Africa where it is most prevalent. With an incidence of over 250…
Biomedical and Health Sciences
Quaternary Ammonium Compounds (QAC) are antimicrobial agents that are used to eliminate bacteria and are found in products that advertise antimicrobial activity. During the ongoing pandemic,…
Biomedical and Health Sciences
TMEM-143 (Transmembrane protein 143) human gene is located in the Chr19q13.33 chromosomal region, which is known to be associated with the risk of type-2 diabetes and cancer. TMEM-143 gene i…
Biomedical and Health Sciences
Fourth Award
Coronavirus, an RNA virus that causes COVID-19, has spread widely around the globe. However, not only RNA-type viruses, but DNA-type also exist. An accurate and portable diagnostic technique…
Biomedical and Health Sciences
Purpose: COVID-19 is a respiratory disease caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) which emerged globally in early 2020. The rapid spread of SARS-CoV-2 spi…
Translational Medical Science
Liver cysts characterize a multitude of illnesses ranging from liver cancer to autosomal dominant polycystic kidney disease (ADPKD). About 1 in 20 people have at least one liver cyst (Cnosse…
Translational Medical Science
COVID-19 is caused by an RNA virus called SARS-CoV-2. PCR testing is a gold-standard method for COVID-19 diagnostic testing. However, there exists no COVID-19 diagnostic test that has the ca…
Biomedical and Health Sciences
Third Award
Background: Substantial research suggests that therapeutic hypothermia could ameliorate the impact of Traumatic Brain Injury (TBI). Our goals were: 1) Study the effects of concussion in a va…
Translational Medical Science
The tyrosine kinase inhibitors (TKIs) Lapatinib and Tucatinib are FDA-approved for the treatment of metastatic HER2-positive breast cancer. However, intestinal side effects, especially sever…
Biomedical and Health Sciences
Hormone therapy is commonly used to treat hormone-related cancers and there has been previous research which suggests that monoclonal antibodies (mAbs) have had a positive therapeutic effect…
Biomedical and Health Sciences
The aim of this research is to investigate the anti cancer activity of the AgEphe ( Silver nanoparticles green synthesis with EtOH extract of the Ephedra aphylla plant) against breast cancer…