Browse real student projects, abstracts, and awards.
ISEF · 2022
Biomedical and Health Sciences
Chemotherapy resistance remains a challenge in treating cancer. There are many factors that can affect resistance, and it is not fully understood. PRPF39 is a pre-mRNA processing factor that…
ISEF · 2022
Biomedical and Health Sciences
Age-related Macular Degeneration (AMD) is a devastating eye disease affecting more than 10 million Americans like my great-grandmother. AMD is a neurodegenerative disease that affects the ma…
ISEF · 2021
Biomedical and Health Sciences
Background: The effective ingredients that are added to cosmetics on the market have concentration limits, which weakens the maximum effect on anti-melanogenic activity. Finding a safer and…
ISEF · 2021
Biomedical and Health Sciences Third Award
The genetic contribution to the development of type 1 diabetes (T1D) remains unclear; however, certain gene variants contribute to the risk of developing this metabolic disorder. Elucidating…
ISEF · 2021
Biomedical and Health Sciences
Chloroquine (CQ), a toxic agent, is an anti-malarial drug used to treat rheumatoid arthritis and systemic lupus erythematosus. Recently, the former Trump administration controversially promo…
ISEF · 2021
Biomedical and Health Sciences Third Award
Air pollution (AP) contains many toxins that collectively harm nearly every organ in the body, and is a key risk factor for many chronic diseases. Aside from its toxic actions, AP may alter…
ISEF · 2021
Biomedical and Health Sciences
Cancer is the cause of every sixth death globally with inadequate screening attributing to 40,000 deaths in the U.S. annually. An alternative to current genetic mutation screening efforts is…
ISEF · 2021
Translational Medical Science
According to the National Cancer Institute, distress is an emotional, social, spiritual, or physical pain or suffering that may cause a person to feel sad, afraid, depressed, anxious, or lon…
ISEF · 2021
Translational Medical Science Fourth Award
Alzheimer’s Disease (AD) is the most widespread neurodegenerative disease, affecting over 50 million people across the world. While its progression cannot be stopped, early and accurate diag…
ISEF · 2021
Biomedical and Health Sciences Third Award
In 2016, over 1.9 billion adults were overweight or obese and the obesity epidemic, often associated with high-income societies, is now on the rise in low- and middle-income countries. In re…
ISEF · 2021
Biomedical and Health Sciences
Purpose: Because of lack of time to participate in sports, Chinese adolescents' physical health status has declined year by year. To prevent and control pneumonia caused by the novel coronav…
ISEF · 2021
Translational Medical Science Fourth Award
Affordably Examining Your Eyes [A-EYE] is a multistage artificial intelligence platform that detects eye conditions through retinal fundus images. Unlike previous attempts of deep learning d…
ISEF · 2021
Translational Medical Science Fourth Award
Systemic Scleroderma (SSc) is a severe autoimmune disease, characterized by immune abnormality, vasculopathy, and fibrosis. Clinically, SSc has no cure. Although the Chinese herb Astragalus…
ISEF · 2021
Biomedical and Health Sciences First Award
After losing my grandfather to COPD, I was determined to develop an accessible method for diagnosis of chronic respiratory illnesses. The objective of my project was to design and create a h…
ISEF · 2021
Translational Medical Science
Colorectal cancer (CRC) is not only one of the most common non-sex-specific cancers, but also one of the most deadly. Early diagnosis and treatment, however, can significantly improve patien…
ISEF · 2021
Translational Medical Science
Cardiac arrhythmias occur when the electrical impulses that coordinate heart beats don't work properly. In the U.S., they cause over a million hospitalizations and over 200,000 sudden cardia…
ISEF · 2021
Biomedical and Health Sciences Fourth Award
Immunotherapy has revolutionized some cancer treatments. Yet, the same treatments showed disappointing outcomes for most prostate cancer patients, with five-year survival rates of 99% for ea…
ISEF · 2021
Translational Medical Science Third Award
Parkinson’s disease (PD) is the leading cause of disability worldwide. Indeed, PD cases are rapidly rising, especially in underdeveloped areas that don’t have ready access to therapeutic car…
ISEF · 2021
Translational Medical Science
Atopic dermatitis (AD) is a common chronic skin disorder most prevalent in children around the world. It causes red and scaly skin with constant itching symptoms. Genetically, the condition…
ISEF · 2021
Biomedical and Health Sciences
The conventional use of current therapeutic approaches to treat metastatic cancers is limited. Kinesin Family 19 (KIF19) is a microtubule-associated protein involved in cell motility and has…
ISEF · 2021
Biomedical and Health Sciences
The most commonly administered chemotherapeutic agent in Glioblastoma (GBM) treatment, Temozolomide (TMZ), fails to generate a clinically significant response in over 50% of patients due to…
ISEF · 2021
Translational Medical Science
Acute kidney injury (AKI) is the sudden onset of kidney damage in which the kidneys cannot filter waste from the blood, requiring emergency hospitalization. AKI patient mortality rate is hig…
ISEF · 2021
Translational Medical Science
Colorectal cancer(CRC) ranks third in occurrence and second in mortality among all cancers. Current CRC identification methods are often ineffective due to the invasiveness of such procedure…
ISEF · 2021
Biomedical and Health Sciences
Innate immune response is the protective response of the human body to defend against harmful invaders. However, excessive or dysregulated inflammation may harm human body. Steroids are ofte…
ISEF · 2021
Translational Medical Science
Shown to ameliorate the symptoms or even target the root pathology of conditions ranging from cancer to chronic pain, cannabis and its derivatives have the potential to improve the quality o…
ISEF · 2021
Translational Medical Science Fourth Award
I strongly believe that a cost-effective, highly sensitive, and easy-to-use Point of Care (POC) multi-biomarker diagnostic device has the potential to increase health equity, this is especia…
ISEF · 2021
Biomedical and Health Sciences
Shiga toxin-producing E. coli-induced convulsions/seizures will affect the expressions of Drosophila melanogaster (common fruit flies). This is due to the fact that Shiga toxin-producing E.…
ISEF · 2021
Translational Medical Science
Alzheimer’s Disease (AD), a type of dementia, is attributed to the overproduction of the amyloid-beta (Aß) protein caused by the cleavage of the amyloid precursor protein. This project focus…
ISEF · 2021
Biomedical and Health Sciences
Do spices affect you in a way you don’t want to be affected? Perhaps you want to be relieved from the pain you suffer. Well my experiment might have what you are looking for! The results I f…
ISEF · 2021
Biomedical and Health Sciences
BACKGROUND- Three million people in the U.S alone suffer from gluten intolerance/celiac disease. My aim is to identify which of the natural fruits, and herbs have the ability to breakdown gl…