Browse real student projects, abstracts, and awards.
ISEF · 2024
Biomedical and Health Sciences
Alzheimer's disease, a progressive neurodegenerative disorder marked by the accumulation of beta-amyloid plaques in the brain, has become a global issue; One without a cure. Recent research…
ISEF · 2024
Translational Medical Science Fourth Award
Gastrointestinal cancers affect 1.1 million people and are responsible for >875K deaths annually, making them the third leading cause of cancer death worldwide. Late detection of recurrence…
ISEF · 2024
Translational Medical Science
Lung cancer diagnosis presents significant challenges, especially in the early stages when tumor biomarkers are difficult to detect. Manual diagnosis relies heavily on the experience of radi…
ISEF · 2024
Biomedical and Health Sciences
Cassia auriculata is a medicinal plant traditionally claimed to be a remedy against DM. Previous literature has revealed the antidiabetic potency of C. auriculata employing various animal mo…
ISEF · 2024
Biomedical and Health Sciences First Award
Primates had evolved an advanced spermatogonia stem cell (SSC) system that correlates with reduced germline mutations and longer lifespans, yet the underlying mechanism remains poorly unders…
ISEF · 2024
Translational Medical Science Fourth Award
Major Depressive Disorder (MDD) affects over 280 million individuals globally, but less than 25% of those affected receive proper care. Early detection is vital for timely intervention and t…
ISEF · 2024
Translational Medical Science
Nearly 6.7 million Americans age 65+ are currently affected by Alzheimer's disease (AD). Preliminary diagnosis of AD is a difficult and time-consuming process that often leads to false outco…
ISEF · 2024
Translational Medical Science
Breast cancer is the most prevalent type of cancer in women. 31.4% new breast cancer cases in Saudi females were diagnosed in 2020, and more than 2.26 million new case globally. Tamoxifen (T…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
The COVID-19 pandemic caused by the SARS-CoV-2 virus[1], and its secondary bacterial and fungal infections [2-5] have created an urgent need for a new, Small Biological Sampling Volume Diagn…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Systemic lupus erythematosus (SLE) is an incurable chronic autoimmune disease in which the immune system attacks its tissues, causing widespread inflammation and organ damage. Due to the lac…
ISEF · 2024
Biomedical and Health Sciences Third Award
Glioblastoma (GBM) is the most predominant malignant brain cancer in adults without prognosis improvement in decades (average survival interval of 14-17 months). Nevertheless, 83% of GBM cas…
ISEF · 2024
Biomedical and Health Sciences
There are many studies that try to find an effective treatment to combat colon cancer using different types of plants in their research like moss. The research problem is willing the Groutie…
ISEF · 2024
Translational Medical Science
As of 2022, 49% of adolescents and 25% of adults suffer from psychological disorders. Out of those groups, approximately 60% suffer from gastrointestinal disorders. In addition, for the past…
ISEF · 2024
Translational Medical Science Third Award
Cognitive impairment is a common, non-specific early presenting symptom in neurodegenerative diseases, including Alzheimer's disease (AD). A biomarker differentiating AD-related cognitive im…
ISEF · 2024
Biomedical and Health Sciences
This experiment explores how different fermented foods affect signs of insulin resistance in both male and female fruit flies. I hypothesized that if I supplemented fruit fly diets with ferm…
ISEF · 2024
Translational Medical Science
Hypertrophic Cardiomyopathy (HCM) is a heritable heart muscle disease and is the leading cause of sudden cardiac death (SCD) in young adults and teenagers, most notably youth athletes. HCM h…
ISEF · 2024
Biomedical and Health Sciences
I am seeing what form of ibuprofen dissolves the fastest in vinegar, which is a replication of stomach acid. The reason I wanted to do this is because I am surrounded by so many people who g…
ISEF · 2024
Translational Medical Science Third Award
Cancer is a problem that is affecting millions of people worldwide, and it is one of the leading causes of deaths in the U.S. With the increasing number of cancer cases, there’s a higher num…
ISEF · 2024
Biomedical and Health Sciences
Lung Cancer as of the current day is one of the deadliest cancers around the globe due to its high incidence and mortality rates. Identifying factors aiding researchers in developing treatme…
ISEF · 2024
Translational Medical Science
In healthy human cells, telomeres are end caps on DNA strands to protect against degradation. However, as cell replication increases, telomeres progressively shorten, eventually triggering c…
ISEF · 2024
Translational Medical Science
Currently, colorectal cancer is one of the most common cancers in the world, with it contributing to over 10% of all cancers. With colorectal cancer being a significant contributor to the wo…
ISEF · 2024
Biomedical and Health Sciences
The goal of this experiment was to find out whether P. gingivalis derived RagA can bind OC- stamp and promote the RANKL induced osteoclastogenesis. I did this by using RAW 264.5 murine cells…
ISEF · 2024
Biomedical and Health Sciences Third Award
Massive underrepresentation of non-White skin in dermatology research contributes to significant disparities in skin cancer outcomes. Since artificial intelligence (AI) algorithms are largel…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Alzheimer’s is difficult to treat, particularly due to inability of prospective treatments to cross the impermeable blood-brain-barrier(BBB). Neurodegeneration is exacerbated by Aß-aggregate…
ISEF · 2024
Biomedical and Health Sciences Second Award
Our bodies continually encounter genetic and developmental stresses, activating stress-responsive signaling pathways to promote proteostasis. However, when these stresses persist and signali…
ISEF · 2024
Translational Medical Science
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Often covered in biofilms, right sided tumors are deadly and often identified in advanced stages, highlighting t…
ISEF · 2024
Biomedical and Health Sciences
Glyphosate, the active ingredient used in many herbicides, has seen extensive use, surpassing over 1.6 billion kilograms since 1974. With this widespread use, humans have begun to experience…
ISEF · 2024
Biomedical and Health Sciences
Levetiracetam, otherwise known as Keppra, is an anti-seizure medication. It is used to prevent seizures in people who have epilepsy. Due to the fact that Keppra is a preventative medication,…
ISEF · 2024
Biomedical and Health Sciences
Purpose: Age-related macular degeneration (AMD), a devastating neurodegenerative eye disease leading to total blindness, affects 200 million people worldwide. The project focused on identify…
ISEF · 2024
Translational Medical Science
This experiment aimed to continue the search for a cure for celiac disease using mesenchymal stem cells by inhibiting the PD-L1/PD-1 pathway to determine whether it was a contributing factor…