Browse real student projects, abstracts, and awards.
ISEF · 2018
Translational Medical Science
Sucrose in combination with Streptococcus mutans result in acids which break down enamel and contribute to dental caries. Alternatives with potential oral health benefits were explored in th…
ISEF · 2018
Biomedical and Health Sciences Third Award
Type 2 diabetes (T2D), a metabolic disorder characterized by high blood sugar and insulin resistance (IR), has serious socioeconomic ramifications. While T2D is considered a lifestyle diseas…
ISEF · 2018
Biomedical and Health Sciences
Purpose: Stroke is a fatal neurological disease causing severe long-term functional disability in patients. The incident of stroke is rising exponentially, irrespective of age. The beneficia…
ISEF · 2018
Biomedical and Health Sciences
Studying metabolic functions of cancer cells can reveal novel treatment options. For example, increased glutamine uptake drives cancer cell proliferation. The first step in glutamine utiliza…
ISEF · 2018
Translational Medical Science
Chronic inflammation can lead to the buildup of proinflammatory cytokines and result in a plethora of diseases from arthritis to asthma. This has led to a need for safe and natural anti-infl…
ISEF · 2018
Biomedical and Health Sciences
HER2 is a membrane bound protein receptor for cell proliferation. When present in excess, the cell divides uncontrollable and leads to cancer. This type of cancer is very prone to recurrence…
ISEF · 2018
Biomedical and Health Sciences
The studies suggest that in 2050 there will be 9 billion people on Earth. The global expansion of the population and wasteful consumption are going to increase the pressure on future food su…
ISEF · 2018
Translational Medical Science
The purpose of this project was to find an alternative method protocol to treat infections caused by the following pathogens: Escherichia coli, Methicillin-resistant Staphylococcus aureus, a…
ISEF · 2018
Biomedical and Health Sciences
The FOXO transcription factors are part of the Forkhead subfamily O, which contain four members: (FOXO1, FOXO3, FOXO4, and the less well conserved FOXO6) that regulate gene expression involv…
ISEF · 2018
Translational Medical Science
Ketosis is a metabolic state in which some of the body’s energy supply comes from ketone bodies, a product of the breakdown of stored triglycerides. Uncontrolled ketosis leads to an excessiv…
ISEF · 2018
Translational Medical Science
Lack of effective treatment and substantial side effects of current chemotherapy have resulted in poor prognosis for triple-negative breast cancer (TNBC) patients. To avoid these side effect…
ISEF · 2018
Biomedical and Health Sciences
Duchenne muscular dystrophy (DMD) is a severe genetic muscle degeneration disease. Although it is known that DMD is caused by an absence of the protein dystrophin, the exact mechanism of mus…
ISEF · 2018
Biomedical and Health Sciences
Alzheimer’s Disease (AD) is a progressive neurodegenerative disease that causes devastating memory loss and cognitive decline in humans. There is no current cure for AD. Research studies sho…
ISEF · 2018
Translational Medical Science Second Award
The goals of this study were to develop a Drosophila melanogaster model of traumatic brain injury (TBI) using the “High Impact Trauma” (HIT) device to inflict injury and induce vacuolar lesi…
ISEF · 2018
Translational Medical Science
Phenytoin is a commonly used antiepileptic drug. Its effect on causing gingival overgrowth with a prevalence of 50%. This problem caries both hygiene and cosmetic impact on patients. The aim…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
When cancer spreads from one organ to another, it becomes significantly harder to treat. This process, known as metastasis, is involved in 90% of cancer deaths. Because metastasis presents a…
ISEF · 2018
Translational Medical Science
Bacterial vaginosis is a very prevalent women's health issue that affects millions of women worldwide every year, and many current treatments are messy, inconvenient, and ineffective. Theref…
ISEF · 2018
Biomedical and Health Sciences
TMEV, a murine single-stranded positive sense RNA virus, is a model for both multiple sclerosis (MS) and epilepsy, as it results in a demyelinating encephalomyelitis in the CNS, resembling M…
ISEF · 2018
Biomedical and Health Sciences
According to the National Cancer Institute, breast cancer is the most common malignancy in United States women, accounting for more than 40,000 deaths each year. The main cause of death in b…
ISEF · 2018
Biomedical and Health Sciences Third Award
Alzheimer’s Disease affects an estimated 5.4 million people, making it the sixth leading cause of death in the United States. Seeking to increase therapeutic gains, near infrared light (NIR)…
ISEF · 2018
Translational Medical Science
Cardiovascular system diseases are leading causes of mortality worldwide and in all age groups. Moreover, specialists believe that in 90% of cases, cardiovascular diseases can be cured if di…
ISEF · 2018
Translational Medical Science
Purpose: The experiment identified Stearoyl-CoA desaturase 1 (SCD1) as a novel molecular target in Serous Ovarian Carcinoma determined the potential of SSI-4, an SCD1 inhibitor, as a novel m…
ISEF · 2018
Biomedical and Health Sciences
Next-generation intracellular delivery solutions are necessary and will provide essential roles in drug therapeutic applications as well as being critical components of genome editing approa…
ISEF · 2018
Translational Medical Science
The presence of circulating tumor cells (CTCs) in a patient's blood may indicate the aggressiveness of metastatic cancer, and the detection of CTCs can assist physicians in decision making a…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Diabetes is a multi-factorial disorder, characterized by chronic elevation of glucose in the blood. Chronic exposure to high glucose (HG) is a leading cause of cell damage, which is responsi…
ISEF · 2018
Translational Medical Science Fourth Award
A rapid, inexpensive, and non-invasive warning mechanism for imminent stroke and epileptic seizures was developed using gold nanoparticle-hydrogel composites. Stroke is the third leading cau…
ISEF · 2018
Biomedical and Health Sciences Second Award
Cancer immunotherapy is an important alternative to traditional treatments such as chemotherapy and radiation, reducing the toxicity and negative side effects. By eliciting an immune respons…
ISEF · 2018
Biomedical and Health Sciences
The goal of this study was to analyze the expression of SLUG in ovarian cancer. The null hypothesis was that expression of SLUG would be the same between the two tissue types. This study use…
ISEF · 2018
Translational Medical Science
Bisphenol A (BPA), a widely used plastic monomer, is a known estrogen disruptor, which has massive potential implications for public health. Estrogen can cause R-loops, a three-stranded nucl…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Alzheimer’s disease (AD) is one of the most common forms of dementia. The progression of AD occurs in the brain as well as in the eye. The retinal pigment epithelial (RPE) cells were recentl…