Browse real student projects, abstracts, and awards.
ISEF · 2022
Translational Medical Science Third Award
Peripheral Arterial Disease (PAD) is caused by the blockage or narrowing of arteries supplying the lower extremities regions which affects approximately 10% of the U.S population and is one…
ISEF · 2022
Translational Medical Science
Cancer has a major impact on people around the world and is a large burden on society. Ultraviolet (UV) rays damage DNA, which significantly increases the risk of skin cancer, or melanoma. W…
ISEF · 2022
Biomedical and Health Sciences
Neurons, the cells composing the nervous system, are responsible for sending and receiving signals that result in everything from thoughts to movement. Macrophages, a type of cell in the imm…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Glioblastoma Multiforme (GBM) is one of the most lethal and aggressive brain cancers in humans. This project investigated the efficacy of a potential therapy for GBM-The Gliatrap. The Gliatr…
ISEF · 2022
Translational Medical Science
Fecal microbiota transplantation (FMT) is a new approach used for the treatment of inflammatory bowel disease (IBD) since this condition has been linked to an alteration of the gut microbiot…
ISEF · 2022
Biomedical and Health Sciences
In Vietnam, Ardisia gigantifolia is used as the best medicine to treat and prevent some gastric diseases. Ardisia gigantifolia contains saponin that can inhibit the growth of multiple cancer…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Glioblastoma is a malignant tumor of the central nervous system distinguished by its intra-tumoral heterogeneity and inevitable recurrence. A longitudinal axis of genomic evolution has been…
ISEF · 2022
Biomedical and Health Sciences
Alcohol addiction is a significant societal problem negatively impacting millions of people. Understanding the underlying mechanisms of addiction will aid efforts to provide care and a cure…
ISEF · 2022
Biomedical and Health Sciences
Though masks have now become an essential item the application of the now-widespread use of masks is greater than just in the context of protection from COVID-19. Throughout the day, mask-we…
ISEF · 2022
Translational Medical Science
An estimated 93 million adults in the United States are at high risk for serious vision loss, but only half visited an eye doctor in the past year. Prices for eye examinations are drasticall…
ISEF · 2022
Translational Medical Science
Early detection is the key to preventing arrhythmia-related complications. However, developing countries do not have the infrastructure, educated personnel, or devices to screen for arrhythm…
ISEF · 2022
Biomedical and Health Sciences
Mental health is a very prevalent issue in the world today. There are many studies on how physical and mental health affect each other. This study's goal was to discover the relationship bet…
ISEF · 2022
Biomedical and Health Sciences
Age-related macular degeneration (AMD) impacts the retina through an accumulation of unresolved oxidative stress. Diabetic Nephropathy and AMD have a strong association, with an odds ratio o…
ISEF · 2022
Translational Medical Science Second Award
Photosensitive epilepsy (PSE) is a neurological disorder, where seizures are triggered by aberrant flashes or specific spatial configurations of light. After COVID-19, billions of new intern…
ISEF · 2022
Translational Medical Science
Influenza virus causes an estimated 9.0-35.6 million severe illnesses and 850,000 deaths worldwide annually. Aided by its error-prone, open-ended RNA genome, the virus mutates rampantly to e…
ISEF · 2022
Biomedical and Health Sciences
CAR T-cell immunotherapy has proven to be effective in treating relapsed, refractory B-cell malignancies, such as non-Hodgkin’s lymphoma (NHL). Nevertheless, limitations have emerged from IL…
ISEF · 2022
Biomedical and Health Sciences
Purpose: Breast cancer has become one of the most common diseases among women worldwide. Using TS/A cells (established metastasizing adenocacinoma cell line from mouse), I studied the effect…
ISEF · 2022
Translational Medical Science Third Award
Aims: The purpose of this study was to use machine learning algorithms to build an effective, non-invasive and automated pipeline for grading and characterizing gliomas according to WHO 2016…
ISEF · 2022
Biomedical and Health Sciences
Parkinson’s Disease (PD) is the second most common neurodegenerative disease, and it plagues millions of people worldwide. PD is characterized by the loss of dopaminergic neurons, associated…
ISEF · 2022
Biomedical and Health Sciences Third Award
Mus musculus (mice) are often used to model the human immune system and to develop healthcare treatments because mouse immunology accurately recapitulates many aspects of the human immune sy…
ISEF · 2022
Biomedical and Health Sciences
West Nile virus (WNV) is the leading mosquito-borne disease in the United States but is not currently preventable through vaccination or treatable by any medications. It has caused over 2,50…
ISEF · 2022
Translational Medical Science Second Award
Alzheimer's disease (AD) is characterized by toxic aggregates formed by amyloid beta (AB) and tau, which kill memory and learning neurons. With only symptomatic treatments for mild-moderate…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Patients suffering from this condition exhibit a neuroinflammatory response mediated by microglial cells; this response h…
ISEF · 2022
Translational Medical Science
There is an unprecedented global mental health and substance abuse crisis including prescription drugs, affecting adults and youth. A recent FDA guidance requires abuse liability testing in…
ISEF · 2022
Translational Medical Science
The hearts of humans as well as Daphnia magna are striated and neurogenic. In humans, substances that induce sleep also lower blood pressure and heart rate. Research indicates that when D. m…
ISEF · 2022
Biomedical and Health Sciences Second Award
Cardiovascular diseases are the most common cause of death in the world. Because humans form few cardiomyocytes post-birth, engineering new myocardium could transform the treatment of heart…
ISEF · 2022
Translational Medical Science Second Award
This study evaluated the cytotoxicity of two Centella asiatica (CA) methanolic leaf extracts on the metastatic, triple negative breast cancer (TNBC) cell line MDA-MB-231. CA is a plant regio…
ISEF · 2022
Biomedical and Health Sciences
Extracellular vesicles (EVs) also known as Exosomes which are secreted by cells and play functional role in cell-cell communications. Recent advances in EV field have shown that they can be…
ISEF · 2022
Biomedical and Health Sciences
My research investigated the medicinal properties of Lomatium dissectum (called “doza” in our Native language) and Sambucus caerulea (elderberry, “hubui”) under laboratory conditions. Would…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Microplastics in the air cause respiratory diseases and worsen the health of the population, thus a nose filter with a biodegradable membrane may reduce their adverse effects on the respirat…