Browse real student projects, abstracts, and awards.
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Prostate cancer is the second leading cause of death for American men. Sadly, Native Hawaiian men have the highest mortality rate from the disease. Mamaki, an endemic Hawaiian plant and a vi…
ISEF · 2023
Translational Medical Science
With respect to evaluating biopsies for cancer diagnosis, a pressing yet often sidelined issue is that of anatomical pathology errors. Due to the image-based nature of biopsy examinations an…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Along the pathogenesis of Mycobacterium Tuberculosis (MTB), hypoxia-induced dormancy is a process involving the oxygen-depleted environment encountered inside the lung granuloma, where bacil…
ISEF · 2023
Translational Medical Science
Anti-cancer peptides (ACPs), a class of small peptide molecules, have gained increasing attention in cancer research due to their ability to target and kill cancer cells selectively, sparing…
ISEF · 2023
Translational Medical Science
Artificial intelligence is becoming a more widely utilized technology in the healthcare industry to improve predictability and consistency (Science Daily). However, this powerful technology…
ISEF · 2023
Translational Medical Science Third Award
The Kirsten rat sarcoma viral (KRAS) gene is the most frequently mutated oncogene, responsible for many types of highly fatal cancers — notably, pancreatic, colorectal, and non-small cell lu…
ISEF · 2023
Translational Medical Science
In-cell click-formed proteolysis targeting chimera molecules (CLIPTACs) were developed to allow both the inhibition and ubiquitination (degradation) of mutated proteins causing various disea…
ISEF · 2023
Translational Medical Science
Lung cancer is the primary cause of cancer-related deaths worldwide. According to the American Cancer Society, misdiagnoses and lack of early detection are frequent, leading to tumor metasta…
ISEF · 2023
Biomedical and Health Sciences
Age-related macular degeneration (AMD) is a devastating neurodegenerative eye disease that affects the macular region of the retina. Two carotenoids–astaxanthin and lutein–were examined, hyp…
ISEF · 2023
Translational Medical Science Second Award
Several glucometer methods are available for patient-guided glycemic control to reduce the onset of diabetic complications. However, dipstick urine glucose tests using horseradish peroxidase…
ISEF · 2023
Biomedical and Health Sciences
The general increase in demand for biofuels and the use of bio-based materials increases the pressure on agriculture to produce biomass. As a result, huge amount of biomass waste is generate…
ISEF · 2023
Biomedical and Health Sciences Third Award
Caused by the high blood sugar from diabetes, diabetic retinopathy is a disease that damages the blood vessels of the retina. This can lead to blindness and other vision complications. 79% o…
ISEF · 2023
Translational Medical Science
Bacteria are extremely adaptable organisms and genetic mutations developing resistance against antibiotics. According to the World Health Organization (WHO), the inappropriate or excessive u…
ISEF · 2023
Translational Medical Science Third Award
SARS-CoV-1, MERS-CoV and SARS-CoV-2 are highly contagious and lethal coronaviruses (CoVs). Although different forms of anti-SARS-CoV-1 and MERS-CoV vaccines have been developed, none of them…
ISEF · 2023
Biomedical and Health Sciences First Award
422 million adults worldwide have diabetes, and 48% of all juvenile deaths are due to diabetes or diabetes-inflicted diseases; diabetes in low-income families has risen rapidly---up to 21% w…
ISEF · 2023
Biomedical and Health Sciences
Increasing pharmaceutical options assists diversified and individualized healthcare plans (GLIFWC Commission, 1993). Study compares sustainability of traditionally prepared Nuphar advena rhi…
ISEF · 2023
Biomedical and Health Sciences
In the last year, five student-athletes participating in high school basketball tore their ACLs. This project aimed to determine if a correlation exists between the Q-angle of an athlete’s k…
ISEF · 2023
Translational Medical Science
Melanoma is a dangerous form of skin cancer (Rodriguez, 2022). The purpose of this research is to contribute to develop new technologies to limit growth and proliferation of skin melanoma se…
ISEF · 2023
Biomedical and Health Sciences
The purpose of my project is to determine whether there is a significant daily variability regarding sleep efficiency, heart rate variability, and percentage of time in deep non-REM sleep du…
ISEF · 2023
Biomedical and Health Sciences
Drug resistance is one of the greatest obstacles during cancer treatment. It is urgent to solve this clinical issue globally. Previous study indicated that USP24, a deubiquitinase, can promo…
ISEF · 2023
Biomedical and Health Sciences
The importance of dry skin and moisturization is evident in its impact on skin health and quality of life, particularly in dry and low humid environments like Colorado. Moisturization is ess…
ISEF · 2023
Translational Medical Science
Aging is a process involving dynamic changes to the living body over time. From a biological standpoint, it relies on various molecular and cellular factors typically dependent on the enviro…
ISEF · 2023
Biomedical and Health Sciences
Cord blood (CB) hematopoietic stem cells (HSC) are the most promising source for therapy purposes. Such cells are highly proliferative, have low immune reactivity and a lower risk of graft-v…
ISEF · 2023
Translational Medical Science
Fetal monitoring based on cardiotocography (CTG) is a non-invasive option for assessing fetal health. However, current methodologies of interpreting CTG consist of human eye inspection, resu…
ISEF · 2023
Biomedical and Health Sciences
This proposal is made of 4 separate parts, each with their own functions, the first one is “the Headset”, it’s a small squishy box which contains the temperature sensor, and will be tied up…
ISEF · 2023
Biomedical and Health Sciences
Alternative splicing is a process that occurs during gene expression, in which a gene codes for multiple proteins by including or excluding segments (exons) from the mRNA transcript. The spl…
ISEF · 2023
Translational Medical Science Second Award
Rheumatoid arthritis (RA) is an autoimmune joint disease that affects nearly 1% of people worldwide. RA disproportionately affects women, indigenous peoples, and those of lower socioeconomic…
ISEF · 2023
Translational Medical Science Second Award
Diabetes mellitus is a global concern, and early detection can prevent serious complications. 50% of people live with undiagnosed diabetes, disproportionately afflicting low-income groups. N…
ISEF · 2023
Translational Medical Science
Low testosterone may be a novel risk factor for prediabetes. We assessed associations between prediabetes and total serum testosterone (TT), and whether the associations were modified by pop…
ISEF · 2023
Biomedical and Health Sciences Second Award
Obesity is a severe health problem predicted to affect one in two U.S. adults by 2030. Leptin, an adipocyte-derived satiety-inducing peptide hormone, plays a critical role in mediating food…