20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2024
Translational Medical Science
Each year, cardiovascular disease(CVD) and cancer account for about 17,900,000 and 10,000,000 mortalities, respectively, worldwide. Both CVD and cancer involve invasive, costly, and dangerou…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Lung and ovarian cancers continue to be leading causes of cancer deaths in the United States, and refining the treatment of these cancers is needed to improve patient survival. The goal of t…
ISEF · 2024
Biomedical and Health Sciences Third Award
Introduction Ventilation (V) and perfusion (Q) remain the main physiologic correlates to assess respiratory gas exchange. Currently several modalities can be used to ascertain V/Q with inhal…
ISEF · 2024
Translational Medical Science
Alzheimer's Disease (AD) causes memory decline beyond normal aging and is the most common cause of dementia. Early detection and intervention can delay the progression of AD and alleviate sy…
ISEF · 2024
Biomedical and Health Sciences
Timely detection of brain tumors is vital in increasing a patient's chance of recovery. Magnetic resonance imaging (MRI) Segmentation is used to detect and diagnose brain tumors, traditional…
ISEF · 2024
Translational Medical Science
Globally, anthropogenic climate change is causing an increase in wildfires, resulting in increased exposure to wildfire smoke. Current literature indicates exposure to a single wildfire smok…
ISEF · 2024
Translational Medical Science
Oral mucositis is a common and debilitating side effect of cancer treatment occurring in 90% of head and neck cancer patients undergoing radiation, 40% of patients with solid tumours receivi…
ISEF · 2023
Translational Medical Science Fourth Award
Renal Cell Carcinoma (RCC) is the deadliest urological disease in the world, accounting for more than 200,000 deaths annually. Detection before metastasis can improve 5-year survival rates d…
ISEF · 2023
Translational Medical Science
Nowadays, liquid biopsies based on detecting cell-free DNA (cfDNA) by Real-Time PCR have gained momentum in cancer diagnosis owing to their painlessness to patients. However, detecting cance…
ISEF · 2023
Translational Medical Science
Epilepsy is characterized by recurrent seizures and is often treated with anti-seizure medications. However, 30% of patients are refractory to this approach and do not experience seizure fre…
ISEF · 2023
Translational Medical Science
Alzheimer's Disease is a brain disorder that slowly deteriorates a person's cognitive function, which controls their executive functions and processing speed. Amyloid-Beta plaques & Tau-Aggr…
ISEF · 2023
Translational Medical Science
This project was created to aid patients who have a potential risk of developing Alzheimer's disease and/or glioblastoma brain tumors due to genetic, environmental, and lifestyle factors. In…
ISEF · 2023
Translational Medical Science
Most drugs function by binding to a “target” receptor, activating or inhibiting the “target” signal transduction pathway, which, in ~50% of drug trials, fails to occur, leading to low effica…
ISEF · 2023
Biomedical and Health Sciences
Microplastics pose a significant threat to sustainability for all organisms as they bring toxic chemicals into the ecosystems. In this novel study, public mass spectrometry datasets were sta…
ISEF · 2023
Translational Medical Science Fourth Award
According to the CDC, approximately 37.3 million people have diabetes mellitus in the US. Diabetic Retinopathy (DR) is a microvascular eye complication associated with diabetes and is the le…
ISEF · 2023
Biomedical and Health Sciences
Recurrent exposure to antibiotics is a form of stress that renders the carcinogenic Helicobacter pylori highly resistant to antimicrobial therapy. To our knowledge, the effect of ozonated AK…
ISEF · 2023
Biomedical and Health Sciences Third Award
Interleukin-6 (IL-6) and Interleukin-8 (IL-8) are cytokines related to general immune function, but within Sickle Cell Anemia (SCA) patients, their overproduction tends to cause autoimmune r…
ISEF · 2023
Biomedical and Health Sciences
Retinitis Pigmentosa (RP) is a common inherited retinal degeneration disease that is caused by the deterioration of rod photoreceptors, a type of retinal cell, leading to vision loss. One me…
ISEF · 2023
Translational Medical Science
COVID-19 and its several strains caused millions of infections and deaths worldwide, making it vital to understand how the virus interacts with human cells. Determining binding site location…
ISEF · 2023
Translational Medical Science
There is currently no definitive screening method or test for Parkinson’s Disease (PD), the second most prevalent neurodegenerative disorder with over 10 million cases worldwide and 1 millio…
ISEF · 2023
Biomedical and Health Sciences
Squid ink–derived nanomelanin has recently demonstrated the radiation protective capacity on the spleen of gamma ray-irradiated mice and X-ray irradiated keratinocyte HaCaT. In this study, w…
ISEF · 2023
Translational Medical Science Second Award
Type I and Type II Diabetes are the number one cause of kidney failure, affecting 422 million people and being responsible for 1.5 million deaths worldwide. The leading upstream cause of dia…
ISEF · 2023
Biomedical and Health Sciences Third Award
As the second leading cause of death, cancer has negatively impacted the lives of millions across the globe both directly and indirectly. In this study, we propose targeting the CaSR (calciu…
ISEF · 2023
Biomedical and Health Sciences
Schizophrenia is a complex brain disorder that affects 1% of the population and is characterized by alterations in cognitive function, acquisition and expression of behaviors not seen in hea…
ISEF · 2023
Translational Medical Science
LED lights are found in most modern technology such as electronics, indoor and outdoor lighting, and novelty items. Because they are so common, they could be affecting our health. The focus…
ISEF · 2023
Translational Medical Science
Screening and early diagnosis is necessary to prevent the recurrence of urinary stones and reduce treatment costs. This study aimed to propose a simple and rapid colorimetric method for dete…
ISEF · 2023
Biomedical and Health Sciences
Potatoes have many health benefits such as providing many vitamins and minerals to the body. However, people that have to have a low potassium diet, such as the renal diet due to lower kidne…
ISEF · 2023
Biomedical and Health Sciences
This study aimed to investigate the role of microRNA (miRNA) variants in Attention Deficit-Hyperactivity Disorder (ADHD). ADHD is characterized by inattention, impulsivity, and sugar craving…
ISEF · 2023
Biomedical and Health Sciences
Malaria is a mosquito-borne disease that caused over 619,000 deaths in 2022, Plasmodium falciparum being the most lethal species which affects humans. Although the disease has affected human…
ISEF · 2023
Translational Medical Science
Among various subtypes of breast cancer, triple-negative breast cancer (TNBC) is well-known as aggressive cancer with frequent anticancer drug-resistance and easy metastasis. Nevertheless, t…