Browse real student projects, abstracts, and awards.
ISEF · 2024
Biomedical and Health Sciences
The second most common skin cancer, Squamous Cell Carcinoma, is a persistent problem that threatens the lives of thousands, yearly. Cellular reproduction is a factor allowing these cancerous…
ISEF · 2024
Biomedical and Health Sciences Third Award
Research Significance: Alzheimer's disease affects nearly 52 million individuals worldwide, with projections indicating a significant increase to 75 million by 2030 and a staggering 152 mill…
ISEF · 2024
Translational Medical Science
Typical cancer treatments like chemotherapy are not targeted treatments and kill healthy cells along with cancer cells, causing negative side effects. Targeted cancer treatments are a soluti…
ISEF · 2024
Biomedical and Health Sciences
A total of 20 hemp and CBD commercial products (4 vape oils, 7 oils, 4 edibles and 5 topicals) were collected from dispensaries and CBD shops. These products were extracted by solvent extrac…
ISEF · 2024
Translational Medical Science
As STEM programs become increasingly popular, the use of coin batteries has also increased. These batteries are used to demonstrate the wonders of electricity to children. However, they come…
ISEF · 2024
Biomedical and Health Sciences
The a-ketoglutarate dehydrogenase complex (KGDHC) enzyme – involved in the Krebs cycle – has been shown to have significantly decreased activity that is thus far unexplained in Alzheimer's d…
ISEF · 2024
Biomedical and Health Sciences
Cisplatin is a platinum based chemotherapy that has been used for over 40 years in cancer treatment. The purpose of this experiment is to examine how cisplatin treatment in breast cancer aff…
ISEF · 2024
Biomedical and Health Sciences
Amyloid-beta is a protein that can misfold into pathological fibril aggregations and lead to the formation of plaques in the brain—one of the hallmarks of Alzheimer’s disease (AD). While the…
ISEF · 2024
Translational Medical Science
Pancreatic Cancer has the lowest survival rates of all cancers due to much diagnosis occurring in the later stages. Methods such as chemotherapy and drug treatments are effective but can lea…
ISEF · 2024
Translational Medical Science
Atopic Dermatitis (AD) is a chronic skin disease which occurs due to many genetic and environmental factors.AD is a disease that can seriously affect the comfort of patients. The barrier pro…
ISEF · 2024
Biomedical and Health Sciences
Objectives The objective of my experiment was to test the effect different diets (high sugar or keto) have on neurodegenerative diseases by measuring basal slowing rate in C. elegans which h…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Breast cancer (BC) is the most frequently diagnosed disease among women, with 2.3 million new cases and 669,000 deaths identified in 2022 alone. Most studies on epigenetic diagnosis biomarke…
ISEF · 2024
Biomedical and Health Sciences
Obesity is a detrimental disease that causes individuals to suffer higher risks for developing cardiovascular diseases, diabetes, and cancer. Recently, a population study found that a loss o…
ISEF · 2024
Biomedical and Health Sciences
Around the world, men and women suffer from several types of breast cancer, among them being triple-negative breast cancer (TNBC). TNBC lacks targeted therapy; therefore, it's commonly treat…
ISEF · 2024
Biomedical and Health Sciences
In recent decades, infertility rates have risen globally, with 11% of women and 9% of men experiencing decreased fertility. Studies pertaining to male fertility are abundant, yet studies of…
ISEF · 2024
Translational Medical Science
The neurodegenerative disease, Amyotrophic Lateral Sclerosis (ALS), is characterized by progressive motor neuron (MN) degeneration leading to muscular atrophy (Scaricamazza et al., 2021). Th…
ISEF · 2024
Biomedical and Health Sciences
Amyotrophic Lateral Sclerosis (ALS), also called Lou Gehrig’s Disease, is an extremely damaging neurodegenerative disorder that attacks the motor system, which gradually weakens and wastes m…
ISEF · 2024
Biomedical and Health Sciences First Award
Osteosarcoma (OS), a primary bone tumor, arises from an imbalance in the bone remodeling pathway which fosters metastasis. In healthy bones, the microenvironment supports balanced remodeling…
ISEF · 2024
Biomedical and Health Sciences
Pancreatic cancer is one of the deadliest diseases in the world. Cancer-associated fibroblasts (CAFs) are an important component of the tumor microenvironment (TME) and important immune-nega…
ISEF · 2024
Translational Medical Science
The usage of DNA methylation at CpG sites within the gene body has the potential to be used as an alternative to promoter methylation for identifying gene expression. In this study, we focus…
ISEF · 2024
Translational Medical Science Fourth Award
As populations around the world grow older and pandemics ravage global health, the burdens of age-related diseases, such as arthritis, heart disease, and cancer, are increasingly prevalent.…
ISEF · 2024
Biomedical and Health Sciences Third Award
Every 15 seconds, a person suffers a traumatic brain injury (TBI), a leading cause of mortality and lifelong disability worldwide. Despite its prevalence, effective therapeutic treatments ta…
ISEF · 2024
Translational Medical Science
Characterized as recalcitrant cancer, small cell lung cancer (SCLC) is a rare neuroendocrine-type lung cancer with growing resistance to immune checkpoint inhibitors, leading to rapid metast…
ISEF · 2024
Translational Medical Science
Most cancer biomarkers are specific to a cancer type(s). By focusing on the most frequently occurring gene mutations across different types of cancers, a multi-gene biomarker was identified…
ISEF · 2024
Biomedical and Health Sciences
Non-alcoholic fatty liver disease (NAFLD), has become a major health problem worldwide and is predicted to become the leading cause of liver transplantation in the United States. In vitro mo…
ISEF · 2024
Translational Medical Science
In many healthcare facilities, the possibility of bedsores forming are a common concern. The formation of bedsores, also called pressure wounds, concern healthcare workers as the deep tissue…
ISEF · 2024
Translational Medical Science
Leukemia is a blood cell cancer ranking 15th in worldwide cancer incidence and 10th in death. The gut microbiome and its metabolites, e.g., short-chain fatty acids like propionate, are thoug…
ISEF · 2024
Biomedical and Health Sciences
Although previous research has studied the subfields of cancer genomics and population genetics separately, they have rarely merged. This study combines the knowledge of mutational signature…
ISEF · 2024
Biomedical and Health Sciences Second Award
1 in 5 people develop cancer in their lifetime. Due to treatment inefficiency, cancer is the leading cause of death worldwide. Deciphering immune cell-cancer cell interactions within the tum…
ISEF · 2024
Translational Medical Science
Alzheimer's disease is a widespread neurodegenerative disorder characterized by abnormal protein accumulation in the brain. From 1990 to 2019, the global burden of Alzheimer's disease and ot…