Translational Medical Science
Afflicting 45 million people worldwide, Alzheimer’s disease (AD) is a neurodegenerative disease that begins 20 years or more before symptoms manifest. Early detection is critical for interve…
Translational Medical Science
First Award
85% of Cholangiocarcinoma, a leading cause of mortality in Thailand and Asian countries, is caused by Orphistorchis viverrini (Ov) infection. “CASCAP” organization proactively diagnoses Ov i…
Translational Medical Science
According to the US Breast Cancer Statistics, Breast Cancer has become the most common cancer in women in the United States. About 1 in 8 US women will develop invasive breast cancer over th…
Biomedical and Health Sciences
Public transportation such as buses often plays music at high decibel levels. Knowing this, I tested my hypothesis that bus music volume is above the safe decibel levels for human hearing, u…
Biomedical and Health Sciences
Fourth Award
Mitochondrial membrane protein associated neurodegeneration (MPAN) is a subtype of a group of rare neurological disorders termed Neurodegeneration with Brain Iron Accumulation (NBIA). MPAN i…
Translational Medical Science
Third Award
Developing clinical Nuclear-factor-kappa-B ( NF-?B) inhibitors persists as an unresolved challenge due to the duality of NF-?B. NF-?B activity in T-cells exerts a protective effect by stimul…
AJAS · 2022
Medicine
Depression is a leading cause of death and disability with more than 264 million people of all ages suffering from the disorder worldwide. Understanding how brain function is altered in depr…
AJAS · 2022
Medicine
Ulcerative Colitis (UC) is a disease hallmarked by continuous inflammation along the gastrointestinal tract, which is largely the consequence of autoimmunity. Its prevalence continues to spr…
Biomedical and Health Sciences
Heart failure is the number one leading cause of death globally (17.9 million deaths annually). Earlier diagnosis is ideal for the implementation of treatment regimens for the patient. Diagn…
Biomedical and Health Sciences
The objective was to compare antibiotic ointments and skin moisturizers’ ability to inhibit bacteria. The hypothesis was antibiotic ointments will inhibit bacterial growth more than skin moi…
Biomedical and Health Sciences
The purpose of this project is to identify the role of glycolytic inhibitors as repurposed drugs for the cure of Covid-19 through virtual screening and test their efficacy against the inhibi…
Biomedical and Health Sciences
Oxygen is critical to sustain aerobic life. Scientists are developing methods to deliver oxygen to stagnant water and human bodies when perfusion, or the movement of gasses across a membrane…
AJAS · 2022
Medicine
Cox Proportional Hazards Assumption Violations in Breast Cancer Gene Expression Data. Background: Cancer is a disease driven by mutations in genes that control cell proliferation, cellular d…
AJAS · 2022
Medicine
Recent advances show that the 14-3-3zeta protein is a unique regulator of IL-17A signal transduction. IL-17A signal transduction triggers two, 14-3-3zeta-TRAF5 and 14-3-3zeta-TRAF6-dependent…
AJAS · 2022
Medicine
The human gut harbors a dynamic population of microorganisms, including bacteria and viruses. The dominant gut microbial phyla are Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria,…
Biomedical and Health Sciences
Second Award
Hormonal breast cancer has a good prognosis compared to other breast cancer subtypes, however, ER-/PR+/HER2-, a hormonal breast cancer type, does not receive the benefits of hormonal therapy…
Biomedical and Health Sciences
First Award
There is currently no cure for chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide with over 70 million cases and 3.5 million deaths per year. Treatment…
Translational Medical Science
Skin cancer is the most common cancer worldwide, with 2 people dying of skin cancer every hour in the United States alone (Skin Cancer Foundation, 2022). However, if detected early (before t…
Translational Medical Science
Fourth Award
Breast cancer is the most diagnosed cancer among women and the 5th leading cause of cancer-related mortality. Women in developing countries, especially sub-Saharan Africa, suffer from the hi…
Biomedical and Health Sciences
First Award
Stroke is the second leading cause of death worldwide, with 15 million people suffering from its debilitating effects each year. 87% of strokes are ischemic, where an artery narrows or becom…
Translational Medical Science
Acute lymphoblastic leukemia (ALL) is one of the most common types of cancer in children. This study investigates a natural product that can be used as a possible agent for the treatment of…
Translational Medical Science
More than 70 countries approve the consumption of artificial sweeteners (Ogungbemi et al., 2019). People, including pregnant women, regularly consume artificial sweeteners to substitute suga…
Biomedical and Health Sciences
Fourth Award
Alzheimers, a degenerative brain disorder, affected 6.1 million Americans in 2021. This debilitating disease is affecting more individuals each year. It disrupts an individual's cognitive ab…
Biomedical and Health Sciences
Purpose: Acute myeloid leukemia (AML) is aggressive cancer with a poor prognosis. Most patients with AML ultimately relapse and succumb to cancer progression after receiving standard treatme…
Translational Medical Science
Fourth Award
Congestive heart failure (CHF) affects millions of patients and is associated with a high mortality rate. Early detection and treatment can improve outcomes and avoid hospitalization, but it…
Translational Medical Science
Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus that has been declared a global pandemic since March 2020. Reverse transcription polymerase chain react…
Translational Medical Science
Fourth Award
1.5 million Americans suffer a traumatic brain injury every year. Without proper rest after even a mild concussion, repeated injuries to the brain build up and can lead to complications such…
Translational Medical Science
Development of Novel, Selective, Orally Available Small Molecule CDK9 Inhibitors for Prostate Cancer Therapy - Mechanistic studies Abstract: Amplification of N-MYC causes its overexpression…
Biomedical and Health Sciences
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more than 33 million people globally. Although several protein hallmarks associated with AD have been identifi…
Translational Medical Science
Acute Myeloid Leukemia, or AML, is a malignant disorder of the bone marrow in which myeloid blasts engulf the bone marrow. To diagnose AML, physicians observe blast cell counts in the marrow…