Browse real student projects, abstracts, and awards.
ISEF · 2016
Translational Medical Science
Alphaviruses are a fascinating group of RNA viruses that belong to the Togaviridae family. Some cause severe diseases, while others have useful attributes as gene expression vectors. In some…
ISEF · 2016
Translational Medical Science First Award
The risk of cardiovascular disease, the world's leading cause of death, is greatly increased by metabolic syndrome, a combination of hyperlipidemia, hypertension, and type-2-diabetes. A rapi…
ISEF · 2016
Translational Medical Science
Nosocomial infections are a potentially lethal and prevalent hazard in the hospital setting. There are over 99,000 associated deaths in American hospitals annually with 1 in 25 hospitalized…
ISEF · 2016
Translational Medical Science
Several drugs, including aminoglycosides and platinum-based chemotherapy agents, are well known for their ototoxic properties. However, the ototoxic potential of most therapeutic compounds i…
ISEF · 2016
Biomedical and Health Sciences
Humans are able to quickly and accurately determine intent from early motions of other agents in the social environment. Through real-time analysis of biomechanical patterns, the mind uses p…
ISEF · 2016
Biomedical and Health Sciences
The purpose of the current study was to determine whether scaling typography to the Golden Ratio improves cognitive fluency, and therefore reading comprehension abilities, in nystagmus patie…
ISEF · 2016
Biomedical and Health Sciences
This study was a continuing fourth year research to develop and evaluate 3 real world applications/interventions to combat obesity. First, an iPhone Application (HFS-App) was developed to he…
ISEF · 2016
Biomedical and Health Sciences
With language being an important method of communication and socialization for children with Down’s Syndrome, innovative technology solutions are increasingly being introduced to help in dev…
ISEF · 2016
Biomedical and Health Sciences
Every day, people all over the world use their cell phones. In recent years, these devices have evolved from simple telecommunications devices into pocket-sized computers. Now equipped with…
ISEF · 2016
Translational Medical Science
Breast cancer (BC) remains to be a prevalent malignancy, as an estimated 231,840 women were diagnosed in the US in 2015. Furthermore, cancer cells now display chemoresistance towards primary…
ISEF · 2016
Translational Medical Science
Cryo Electron Microscopy (Cryo-EM) is a method used to determine the structure of macromolecules. Cryo-EM is used for complexes that are 250kDa or larger and now it is possible to analyze a…
ISEF · 2016
Translational Medical Science
Parkinson's disease(PD) reduces the quality of life for several people. There isn’t exact treatment so it is important to increase the numbers of researches. In our project, we aimed to iden…
ISEF · 2016
Translational Medical Science
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide. UHRF1, a gene essential for DNA methylation, is highly expressed in HCC patients. Transgenic…
ISEF · 2016
Translational Medical Science
The overexpression of PLK1 occurs in many types of cancer. Consequently, the misexpression of PLK1 is used as a diagnosis for specific cancers. Small molecule inhibitors can prevent cancerou…
ISEF · 2016
Biomedical and Health Sciences
Stress in our society is a problem that affects almost everyone. This investigation sought to discover whether high perceived stress levels and the subsequent decrease in prefrontal function…
ISEF · 2016
Biomedical and Health Sciences
Teaching science can be a challenge in basic education, it is necessary for each topic to use specific didactic tools that can relate everyday life concepts with technic elements; tools that…
ISEF · 2016
Translational Medical Science Fourth Award
Nuclear actin, while still poorly understood, plays a role in DNA replication, chromatin organization, and gene expression. This research uses Drosophila oogenesis as a model to study in viv…
ISEF · 2016
Biomedical and Health Sciences
Stress is an integral part of daily life and is often portrayed as a negative phenomenon since it causes physical illness as well as cognitive functions deficits. However, not everybody deve…
ISEF · 2016
Translational Medical Science Fourth Award
Piezo proteins have been identified as key components of mechanosensitive ion channels in humans and other mammals. These channels are in the early stages of characterization; their mechanis…
ISEF · 2016
Biomedical and Health Sciences
Individuals affected by ASD are characterized be a marked different in the ability to communicate and form relationships. New technologies for communication and learning have been used to im…
ISEF · 2016
Translational Medical Science
Hematopoietic system is a complex example of the stem cell concept that provides good opportunities for proliferation and differentiation studies. True hematopoietic stem cell that is charac…
ISEF · 2016
Translational Medical Science
Allergies are an important health issue in our community. We want to develop a drug to lower the effects of allergies by characterizing the IgE receptor in a mast cell. The mast cell is an i…
ISEF · 2016
Translational Medical Science
Kava has been used by Pacific Islanders for years. The purpose of this project was to determine which of the Kava metabolites activate THP-1 macrophages to produce pro/anti-inflammatory cyto…
ISEF · 2016
Translational Medical Science
The purpose of this experiment was to investigate the effects of neuroinflammation and microglial activity on the progression of Alzheimer’s and to develop therapeutics with RNA-Interference…
ISEF · 2016
Translational Medical Science Fourth Award
Atherosclerosis, a form of cardiovascular disease, accounts for 17.3 million deaths/year(Mozaffarian,2014). Characterized by plaque formation in arteries, it leads to myocardial infarctions…
ISEF · 2016
Translational Medical Science
The overall goal of this research is to characterize the functional consequences of mutations in FGFR3 that have been identified in cancer. Fibroblast growth factor receptors (FGFR) belong t…
ISEF · 2016
Biomedical and Health Sciences
In 2011, the number of people in the world that had mobility disabilities was 785 million. Individuals with hemiplegia and paraplegia encounter difficulty in performing their daily routines,…
ISEF · 2016
Translational Medical Science Third Award
This research created a novel system capable of targeting cells based only on their mRNA sequences that would, upon recognition of a predetermined, target, mRNA sequence in a particular cell…
ISEF · 2016
Translational Medical Science Second Award
The goal of the project was to identify effective targeted drugs for inhibiting Protein Glucose Transporter 1 (GLUT1). Findings would be a big step towards curing cancer. GLUT1 transports gl…
ISEF · 2016
Translational Medical Science Fourth Award
Cancer cells metabolize some basic nutrients, such as glucose, differently than normal cells do. Recently, investigation on cancer metabolism has increased due to the discovery of new metabo…