Browse real student projects, abstracts, and awards.
ISEF · 2015
Translational Medical Science Second Award
Alopecia areata (AA) is one the most common autoimmune diseases resulting from T cell mediated destruction of hair follicles. Lack of understanding of immune pathways in AA has restricted AA…
ISEF · 2015
Biomedical and Health Sciences
Rapid technological progress has contributed to the development of a wide range of telemonitoring systems which make treatment and management of chronic diseases as well as danger prevention…
ISEF · 2015
Biomedical and Health Sciences
The focus of this experiment was to study frustration and how it affected dispositional learning for 80 middle/high school students. Each student was given a questionnaire form and their hea…
ISEF · 2015
Biomedical and Health Sciences
This 2nd year research presents a comparison between traditional classroom manipulatives, phase 1 (a set of single-valued radio frequency identification (RFID) magnetic cubes with solo reade…
ISEF · 2015
Biomedical and Health Sciences
Background: This study examines how physical activity and sleep patterns change over time, and how those changes affect physical/mental health among adolescents. Methods: A 3-section survey…
ISEF · 2015
Translational Medical Science
CRISPR/Cas is a prokaryotic defense system that produces complexes that target themselves to and degrade specific foreign nucleic acids, such as virus DNA. The CRISPR/Cas bacteria Streptococ…
ISEF · 2015
Translational Medical Science Third Award
Due to the increasing prevalence of Alzheimer’s Disease (AD) and currently the absence of effective disease modifying drugs, there is a need for improved drug screens to identify plausible A…
ISEF · 2015
Translational Medical Science First Award
After over three decades of HIV vaccine research, no suitable vaccine exists for clinical use today. As a result, a novel HIV vaccine modality is urgently needed. Recently, fifty percent of…
ISEF · 2015
Biomedical and Health Sciences
Schizophrenia is a chronic mental disorder that has a variety of detrimental symptoms and a greater risk factor of suicide. In this study, magnetoencephalography, a noninvasive brain imaging…
ISEF · 2015
Translational Medical Science
Huntington’s disease (HD) is an incurable neurodegenerative disorder characterized by physical, behavioral, and cognitive impairments. It is caused by trinucleotide repeat expansions in the…
ISEF · 2015
Translational Medical Science
Human Mesenchymal Stem Cells (hMSCs) possess a unique immune-regulatory property, which makes them an attractive candidate for cellular therapy for a variety of human diseases such as auto-i…
ISEF · 2015
Translational Medical Science
Lung adenocarcinoma accounts for 27% of cancer deaths. Research in ovarian cancer have evidenced the anticancer properties of ethanol extract of Alpinia purpurata. Protease caspase 3, produc…
ISEF · 2015
Translational Medical Science
Aptamers are short single stranded pieces of DNA with the remarkable ability to bind to cell surface proteins via shape specific recognition. The proper orientation for this shape specific r…
ISEF · 2015
Translational Medical Science
CD47 is a ubiquitously expressed cell surface receptor for thrombospondin-1 and the counter receptor for signal-regulatory protein alpha- (SIRPa). High expression of CD47 on several types of…
ISEF · 2015
Biomedical and Health Sciences
The many current tests for dyslexia and other disabilities are generally expensive, time-consuming, and tedious. This research was done as a continuation of an attempt to see if video could…
ISEF · 2015
Translational Medical Science
The purpose of investigating the biomarker of bladder cancer is to see if there's mutation in the biomarkers' regions since the same biomarker region of angiogenin from ALS was found to be m…
ISEF · 2015
Translational Medical Science
Autophagy is implicated in the pathogenesis of Huntington’s disease (HD), a fatal neurodegenerative disorder, and is unproductive in HD cells. This research focused on understanding cellular…
ISEF · 2015
Biomedical and Health Sciences
The purpose of this research project was to determine if academic performance in primary grades was an indicator of academic performance in high school. It was hypothesized that students’ ac…
ISEF · 2015
Biomedical and Health Sciences
Stress in our society is a problem that affects almost everyone. This investigation sought to discover whether high perceived stress levels are related to lower prefrontal cortex functioning…
ISEF · 2015
Biomedical and Health Sciences
This experiment examines the effectiveness of triggers and effects of jamais vu on students in high school by comparing reports of jamais vu. It was predicted that jamais vu would be trigger…
ISEF · 2015
Translational Medical Science
Neurotransmitter-release is regulated by several pre synaptic proteins where Syntaxin and Complexin are crucial. The locomotor activity of Drosophila Melanogaster adult animals was evaluated…
ISEF · 2015
Biomedical and Health Sciences
This experiment developed a technique for improved quantitative diagnosis of mental disorders using intentionally ambiguous feedback in traditional pattern recognition testing. Pattern recog…
ISEF · 2015
Biomedical and Health Sciences
A method is described for the analysis of cotinine, as a metabolite of nicotine, in saliva samples. The aim of this method is to compare cotinine levels between two groups of both non-smokin…
ISEF · 2015
Biomedical and Health Sciences
Alzheimers Disease is a neurodegenerative disease resulting in loss of brain function and memory, caused by the build-up of Amyloid-beta (Abeta) protein plaques and neurofibrillary tangles.…
ISEF · 2015
Translational Medical Science
Colorectal cancer arises from genetic aberrancies classified as driver mutations, which actively promote disease progression, and passenger mutations that provide no evident selective growth…
ISEF · 2015
Translational Medical Science Fourth Award
Mitochondria are the "energy factories" of the cell. Their main function is ATP production, and they are normally thumb-shaped with lamellar cristae. Mitochondrial morphology regulates apopt…
ISEF · 2015
Translational Medical Science Third Award
Chronic inflammation contributes to the pathogenesis of seven of the ten leading causes of mortality in the U.S. However, current anti-inflammatory drugs are oftentimes ineffective and/or cy…
ISEF · 2015
Biomedical and Health Sciences
The complex hormonal mechanisms of the autonomic nervous system provide the physiological conditions necessary to cope with a sudden crisis or emergency. Chronically stressful conditions cau…
ISEF · 2015
Translational Medical Science
The purpose of this experiment was to investigate the effects of an inflammation response on the synthesis of transcription factor CREB in MAPT gene regulation and hyper-phosphorylation of t…
ISEF · 2015
Translational Medical Science
Transcriptional promoters play an important role in bacterial gene regulation. Many promoters have a conserved DNA sequences called the -35 element and the -10 element. This study was to int…