20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2024
Translational Medical Science
Hypertrophic Cardiomyopathy (HCM) is a heritable heart muscle disease and is the leading cause of sudden cardiac death (SCD) in young adults and teenagers, most notably youth athletes. HCM h…
ISEF · 2024
Biomedical and Health Sciences
I am seeing what form of ibuprofen dissolves the fastest in vinegar, which is a replication of stomach acid. The reason I wanted to do this is because I am surrounded by so many people who g…
ISEF · 2024
Translational Medical Science Third Award
Cancer is a problem that is affecting millions of people worldwide, and it is one of the leading causes of deaths in the U.S. With the increasing number of cancer cases, there’s a higher num…
ISEF · 2024
Biomedical and Health Sciences
Lung Cancer as of the current day is one of the deadliest cancers around the globe due to its high incidence and mortality rates. Identifying factors aiding researchers in developing treatme…
ISEF · 2024
Translational Medical Science
In healthy human cells, telomeres are end caps on DNA strands to protect against degradation. However, as cell replication increases, telomeres progressively shorten, eventually triggering c…
ISEF · 2024
Translational Medical Science
Currently, colorectal cancer is one of the most common cancers in the world, with it contributing to over 10% of all cancers. With colorectal cancer being a significant contributor to the wo…
ISEF · 2024
Biomedical and Health Sciences
The goal of this experiment was to find out whether P. gingivalis derived RagA can bind OC- stamp and promote the RANKL induced osteoclastogenesis. I did this by using RAW 264.5 murine cells…
ISEF · 2024
Biomedical and Health Sciences Third Award
Massive underrepresentation of non-White skin in dermatology research contributes to significant disparities in skin cancer outcomes. Since artificial intelligence (AI) algorithms are largel…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Alzheimer’s is difficult to treat, particularly due to inability of prospective treatments to cross the impermeable blood-brain-barrier(BBB). Neurodegeneration is exacerbated by Aß-aggregate…
ISEF · 2024
Biomedical and Health Sciences Second Award
Our bodies continually encounter genetic and developmental stresses, activating stress-responsive signaling pathways to promote proteostasis. However, when these stresses persist and signali…
ISEF · 2024
Translational Medical Science
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Often covered in biofilms, right sided tumors are deadly and often identified in advanced stages, highlighting t…
ISEF · 2024
Biomedical and Health Sciences
Glyphosate, the active ingredient used in many herbicides, has seen extensive use, surpassing over 1.6 billion kilograms since 1974. With this widespread use, humans have begun to experience…
ISEF · 2024
Biomedical and Health Sciences
Levetiracetam, otherwise known as Keppra, is an anti-seizure medication. It is used to prevent seizures in people who have epilepsy. Due to the fact that Keppra is a preventative medication,…
ISEF · 2024
Biomedical and Health Sciences
Purpose: Age-related macular degeneration (AMD), a devastating neurodegenerative eye disease leading to total blindness, affects 200 million people worldwide. The project focused on identify…
ISEF · 2024
Translational Medical Science
This experiment aimed to continue the search for a cure for celiac disease using mesenchymal stem cells by inhibiting the PD-L1/PD-1 pathway to determine whether it was a contributing factor…
ISEF · 2024
Biomedical and Health Sciences
Hardikar Syndrome (HS) is a rare genetic disorder characterized by cleft lip/palate, pigmentary retinopathy, intestinal malrotation, and hepatobiliary disease. The disease is known to be cau…
ISEF · 2024
Biomedical and Health Sciences
Alzheimer's Disease(AD) affects more than 6 million people in the US, by causing degeneration of the brain cells, deficiency of cognition and mobility, and even death. As aging progresses, s…
ISEF · 2024
Translational Medical Science Fourth Award
Despite its incurable nature, MSK Life Sync offers AI-driven support to manage Medullary Sponge Kidney (MSK) disease to enhance life quality for sufferers, including children. As highlighted…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Water pollution is a critical threat to human health as it can lead to increased cancer risk. More than 22 carcinogens can be found in the drinking water, including heavy metals such as lead…
ISEF · 2024
Biomedical and Health Sciences
Purpose: Cutaneous melanoma causes over 8,000 deaths annually in the U.S. Survival differences may be linked to tumor-infiltrating lymphocytes (TILs), white blood cells that eliminates cance…
ISEF · 2024
Translational Medical Science
Latin Americans are the ethnic group with the second highest prevalence of Alzheimer's disease cases. However, most studies on this condition have been conducted in European populations. To…
ISEF · 2024
Translational Medical Science
Our software system is designed to assist medical personnel in early diagnosing and prognosticating of Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease that is often misdiagn…
ISEF · 2024
Translational Medical Science
Malaria is a deadly disease that claims the lives of over 460,000 children annually. Current diagnostic methods use labor-intensive microscopy to image Giemsa-stained blood smears, limiting…
ISEF · 2024
Translational Medical Science
This experiment studies if a restricted diet improves the health of pregnant BPH/5 mice and their offspring. BPH/5 mice have high blood pressure during pregnancy, which mimics the symptoms o…
ISEF · 2024
Translational Medical Science
Acute kidney failure (AKF) is a worldwide growing clinical problem affecting over 13 million people and resulting in 1.7 million deaths annually. AKF symptoms are not noticeable in the early…
ISEF · 2024
Translational Medical Science
Alzheimer's disease (AD) is the most common age-related neurodegenerative disease that affects memory and learning. Mitochondria are critical to neuronal function in the brain, and energy me…
ISEF · 2024
Translational Medical Science First Award
Every 3 seconds, someone in the world develops Dementia. By 2050, over 139 million people worldwide will be living with Dementia. Early interventions are crucial in preventing and treating D…
ISEF · 2024
Biomedical and Health Sciences
The purpose of my project is to explore the effects of radiation on daphnia, and the radiation emitted under different apps and settings. What if the part of the reason people got tumors was…
ISEF · 2024
Biomedical and Health Sciences
The California heat waves of 2022 were the most severe on record and will likely increase in the coming years. The increasing heat wave intensities, a common worldwide phenomenon in coastal…
ISEF · 2024
Biomedical and Health Sciences
Osteosarcoma, most commonly found in children, originates in the bones and spreads throughout the body over time. Over the last 30 years, the mortality rate for osteosarcoma has not improved…