Browse real student projects, abstracts, and awards.
ISEF · 2024
Translational Medical Science
Around 800 million individuals worldwide are estimated to have chronic kidney disease (CKD), with most cases being undiagnosed. Diagnosing CKD and other renal dysfunctions requires an assess…
ISEF · 2024
Biomedical and Health Sciences
I characterized placenta and fetal brain tissues on the cellular level by leveraging single-cell (sc)RNA-seq data from pregnant pigtail macaques (Macaca nemestrina). My hypothesis was that t…
ISEF · 2024
Translational Medical Science Second Award
Across neurological drug development, researchers struggle with the inability of most drugs to pass through the blood-brain barrier (BBB), due to the semipermeable membrane’s high selectivit…
ISEF · 2024
Translational Medical Science
Currently, 6.2 million adults suffer from heart failure (HF), with 30-40% surviving one-year post-hospitalization and a 30-day readmission rate of 23%. The urgent need for an affordable, spe…
ISEF · 2024
Translational Medical Science
Biodegradable polymers are often used to seek applications addressing specific needs, such as wound care, due to their compatibility with biological interfaces, are eco-friendly, and safe fo…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Adoptive Cell Therapy (ACT) is a promising form of Immunotherapy, wherein T-Lymphocytes are propagated in the laboratory and re-infused into patients. However, a major limitation to ACT is C…
ISEF · 2024
Biomedical and Health Sciences
Triple-negative breast cancer (TNBC) is a molecular subset of breast cancer defined by a lack of estrogen, progesterone, and the human epidermal growth factor 2 (HER2) receptors. Currently,…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
UGT1A1 is an enzyme involved in metabolizing Irinotecan, a DNA topoisomerase class I inhibitor chemotherapeutic drug. Polymorphisms within the UGT1A1 promoter reduce UGT1A1 mRNA expression,…
ISEF · 2024
Translational Medical Science
Commonly known as the yellow water lily root or kaandoosh in Ojibwe language, the rhizome of Nuphar advena is utilized by Indigenous communities for treating bacterial overgrowth. This study…
ISEF · 2024
Biomedical and Health Sciences
Ankylosing Spondylitis a type of rheumatic autoimmune disorders where normal body cells attack musculoskeletal cells, making bones' weak joints unstable and prone to fractures. This can caus…
ISEF · 2024
Biomedical and Health Sciences
Colorectal Cancer (CRC) is the second leading cause of cancer death. This is because during early stages, CRC is difficult to catch, which means that treatment can only be offered after the…
ISEF · 2024
Translational Medical Science
Decidualization is a key process in the endometrium, facilitating embryo implantation through morphological changes of the endometrium. Dysregulation of this process is prevalent in individu…
ISEF · 2024
Biomedical and Health Sciences
UV light damages every ocular structure including the cornea, lens, and the retina. Although anterior structures of the eye absorb 99% of UV light, some UV radiation does reach the retina. C…
ISEF · 2024
Translational Medical Science
Dengue virus (DENV-III) has been declared an epidemic in many Southeastern Asian and Eastern African nations; its highest incidence rate is in Bangladesh. Bangladesh set the precedent for en…
ISEF · 2024
Translational Medical Science Third Award
Every 2 seconds, cardiovascular disease (CVD) steals a life. 12-lead electrocardiography (ECG) is the gold standard for CVD diagnosis, which is specialist-reliant and mainly available in urb…
ISEF · 2024
Biomedical and Health Sciences
Alzheimer's disease, a progressive neurodegenerative disorder marked by the accumulation of beta-amyloid plaques in the brain, has become a global issue; One without a cure. Recent research…
ISEF · 2024
Translational Medical Science Fourth Award
Gastrointestinal cancers affect 1.1 million people and are responsible for >875K deaths annually, making them the third leading cause of cancer death worldwide. Late detection of recurrence…
ISEF · 2024
Translational Medical Science
Lung cancer diagnosis presents significant challenges, especially in the early stages when tumor biomarkers are difficult to detect. Manual diagnosis relies heavily on the experience of radi…
ISEF · 2024
Biomedical and Health Sciences
Cassia auriculata is a medicinal plant traditionally claimed to be a remedy against DM. Previous literature has revealed the antidiabetic potency of C. auriculata employing various animal mo…
ISEF · 2024
Biomedical and Health Sciences First Award
Primates had evolved an advanced spermatogonia stem cell (SSC) system that correlates with reduced germline mutations and longer lifespans, yet the underlying mechanism remains poorly unders…
ISEF · 2024
Translational Medical Science Fourth Award
Major Depressive Disorder (MDD) affects over 280 million individuals globally, but less than 25% of those affected receive proper care. Early detection is vital for timely intervention and t…
ISEF · 2024
Translational Medical Science
Nearly 6.7 million Americans age 65+ are currently affected by Alzheimer's disease (AD). Preliminary diagnosis of AD is a difficult and time-consuming process that often leads to false outco…
ISEF · 2024
Translational Medical Science
Breast cancer is the most prevalent type of cancer in women. 31.4% new breast cancer cases in Saudi females were diagnosed in 2020, and more than 2.26 million new case globally. Tamoxifen (T…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
The COVID-19 pandemic caused by the SARS-CoV-2 virus[1], and its secondary bacterial and fungal infections [2-5] have created an urgent need for a new, Small Biological Sampling Volume Diagn…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Systemic lupus erythematosus (SLE) is an incurable chronic autoimmune disease in which the immune system attacks its tissues, causing widespread inflammation and organ damage. Due to the lac…
ISEF · 2024
Biomedical and Health Sciences Third Award
Glioblastoma (GBM) is the most predominant malignant brain cancer in adults without prognosis improvement in decades (average survival interval of 14-17 months). Nevertheless, 83% of GBM cas…
ISEF · 2024
Biomedical and Health Sciences
There are many studies that try to find an effective treatment to combat colon cancer using different types of plants in their research like moss. The research problem is willing the Groutie…
ISEF · 2024
Translational Medical Science
As of 2022, 49% of adolescents and 25% of adults suffer from psychological disorders. Out of those groups, approximately 60% suffer from gastrointestinal disorders. In addition, for the past…
ISEF · 2024
Translational Medical Science Third Award
Cognitive impairment is a common, non-specific early presenting symptom in neurodegenerative diseases, including Alzheimer's disease (AD). A biomarker differentiating AD-related cognitive im…
ISEF · 2024
Biomedical and Health Sciences
This experiment explores how different fermented foods affect signs of insulin resistance in both male and female fruit flies. I hypothesized that if I supplemented fruit fly diets with ferm…