Browse real student projects, abstracts, and awards.
ISEF · 2025
Translational Medical Science
Oral cancer kills over 300,000 lives across the world every year, and oral squamous cell carcinoma (OSCC) is a dominant type of oral cancer. Current diagnosis steps for OSCC typically involv…
ISEF · 2025
Biomedical and Health Sciences
Chimeric Antigen Receptor (CAR) T Cells and Bispecific T Cell Engagers (BiTEs) have revolutionized the treatment of relapsed/refractory hematologic cancers. However, there are no head-to-hea…
ISEF · 2025
Translational Medical Science
Psoriasis is a chronic immune-mediated inflammatory disorder affecting over 125 million individuals worldwide, characterized by keratinocyte hyperproliferation and dysregulated inflammatory…
ISEF · 2025
Translational Medical Science
Malaria is a devastating disease that kills over half a million people annually. Research shows the Plasmodium falciparum protozoan disrupts iron regulation by degrading ferroportin, allowin…
ISEF · 2025
Translational Medical Science
This project presents the development of three AI-powered diagnostic tools capable of identifying malaria, leukemia, and anemia from peripheral blood smear (PBS) images using convolutional n…
ISEF · 2025
Translational Medical Science
Pancreatic Ductal Adenocarcinoma (PDAC), responsible for over 90% of pancreatic cancer cases, remains one of the most lethal cancers due to stage IV diagnosis and five-year survival rate of…
ISEF · 2025
Biomedical and Health Sciences
Liver cancer is the third leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) as the most common type. HCC shows disparities across race, gender, and ethnic…
ISEF · 2025
Biomedical and Health Sciences
Heart disease is the leading cause of death for both men and women in the United States, and is responsible for a third of deaths worldwide. Most cardiovascular disease is caused by the accu…
ISEF · 2025
Translational Medical Science
Pancreatic cancer is the “king of cancer” due to its aggressiveness and high lethality. Although it ranks 9th in incidence, it is the 4th leading cause of cancer-related death, and is projec…
ISEF · 2025
Biomedical and Health Sciences
Thyroid cancer (TC) is the fastest-growing cancer worldwide, with non-cancerous thyroid tumors affecting 60% of the population. Current methods for detecting TC are often radioactive or high…
ISEF · 2025
Translational Medical Science
Oncolytic measles virus (MV) strains can be engineered to express therapeutic transgenes and are currently undergoing clinical trials for cancer treatment. Detecting MV infection in tumor ti…
ISEF · 2025
Translational Medical Science
The CDC and WHO report around 650,000 Neisseria gonorrhoeae (Ng) infections in the U.S and more than 80 million worldwide. Current diagnostic methods for Ng, mainly nucleic acid amplificatio…
ISEF · 2025
Translational Medical Science
Radiation exposure globally results in 2-3 million skin cancers annually. This project proposed an alternative non-synthetic, environmentally safe, multifunctional UV filter. Preliminary res…
ISEF · 2025
Biomedical and Health Sciences
As neurodegenerative diseases such as Alzheimer’s affect over 70 million individuals, it is crucial to investigate modifiable lifestyle factors such as diet and circadian rhythm patterns to…
ISEF · 2025
Translational Medical Science
The issue of mental health misdiagnosis, affecting more than a third of patients with severe psychiatric disorders (39.16%) according to the National Institute of Health, calls for urgent ac…
ISEF · 2025
Biomedical and Health Sciences
Nicotine addiction is the leading cause of preventable death worldwide. The National Institute on Drug Abuse (NIDA) reports approximately 23.6 million Americans have a nicotine use disorder.…
ISEF · 2025
Translational Medical Science
Diabetes Mellitus is a growing global epidemic, affecting over 500 million people worldwide. The condition is characterized by insulin resistance- failure of body’s cells to respond effectiv…
ISEF · 2025
Translational Medical Science
Autoimmune diseases affect millions worldwide, yet many are difficult to diagnose due to biological complexity and variability across patients. I developed a computational pipeline to addres…
ISEF · 2025
Biomedical and Health Sciences
Beta-carotene is found in most living organisms and contributes to the red, orange, and yellow coloration in various life forms. In humans, beta-carotene is converted into vitamin A, which p…
ISEF · 2025
Translational Medical Science
Purpose: Understanding the coordination of glucose metabolism across brain regions can provide insights into energy distribution in cerebral function. This study aims to explore the interreg…
ISEF · 2025
Translational Medical Science
Conventional methods for Alzheimer's Disease (AD) early diagnosis are often considered not cost-effective and sometimes invasive. Although recent AD studies focus on blood biomarker-based me…
ISEF · 2025
Biomedical and Health Sciences
Long Covid (LC) is a condition that can occur after Sars-Cov-2 infection or as a result of vaccinations (Post-Covid Vaccination Syndrome (PCVS)). There is a wide range of over 200 registered…
ISEF · 2025
Biomedical and Health Sciences
Gut microbes play an important role in maintaining our health and disease susceptibility. Multiple diseases including type 2 diabetes (T2DM), obesity, and metabolic syndrome are associated w…
ISEF · 2025
Biomedical and Health Sciences
Endometriosis is associated with infertility in 30% to 50% of the millions affected worldwide. Decidualization, a key endometrial differentiation process that facilitates embryo implantation…
ISEF · 2025
Biomedical and Health Sciences
Knee arthroplasty for severe arthritis is being frequently performed worldwide in varied clinical settings due to increased patient awareness and longer life expectancy. Intraoperative vascu…
ISEF · 2025
Translational Medical Science
There is an increasing consumer demand for effective natural products with fewer synthetic chemicals. In the United States, antiperspirants and deodorants are very common hygiene items used…
ISEF · 2025
Translational Medical Science
Radiology, an important branch of medicine, relies on imaging techniques such as X-rays to diagnose diseases and injuries, yet a shortage of radiologists in underserved areas causes delays i…
ISEF · 2025
Translational Medical Science
Studies have shown that, compared to other racial/ethnic groups in the United States, Puerto Rican children have disparities that result in higher prevalence of chronic diseases and rates of…
ISEF · 2025
Biomedical and Health Sciences
The ketogenic diet is commonly used to prevent seizures in children with drug-resistant epilepsy. However, due to its unpleasant taste and difficulty in adherence, many children must receive…
ISEF · 2025
Biomedical and Health Sciences
An estimated 30-50% of people with HIV experience HAND (HIV-associated neurocognitive disorder). HAND may be influenced by ferroptosis, i.e., iron-regulated cell death linked to oxidative st…