Browse real student projects, abstracts, and awards.
ISEF · 2026
Biomedical Engineering
This project designs anti-cancer peptides that inhibit PDEd, a chaperone regulating KRAS signaling. Using the PDEd crystal structure (PDB: 4JV6), RFdiffusion generated peptide backbones, Pro…
ISEF · 2026
Biomedical Engineering
Elopement/wandering affects nearly 49% of children with Autism Spectrum Disorder (ASD), and 71% of these cases result in fatal outcomes. Existing tracking systems rely on cellular subscripti…
ISEF · 2026
Biomedical Engineering
Distal pulse assessment during closed fracture reduction in pre-hospital emergency care is typically performed intermittently and subjectively, leaving windows where vascular compromise may…
ISEF · 2026
Biomedical Engineering
Background Heart failure affects 64 million people annually. Transplants are in chronic shortage, especially for pediatric patients. Total artificial heart (TAH) promises a solution; however…
ISEF · 2026
Biomedical Engineering
Ovarian cancer subtype diagnosis in current clinical practice remains challenging because it relies on expert pathologists and advanced computational infrastructure, which are often unavaila…
ISEF · 2026
Biomedical Engineering
The growing prevalence of antibiotic-resistant bacterial infections has impacted tens of millions of lives by reducing antibiotic effectiveness and worsening infections, which increases heal…
ISEF · 2026
Biomedical Engineering
OralSense is a smart toothbrush system designed for passive, non-invasive detection of early gingival disease and pre-diabetes risk during routine brushing. It consists of a reusable electro…
ISEF · 2026
Biomedical Engineering
Nearly half of the world's population, 47%, has little to no access to diagnostic testing, which can delay care until conditions become critical. This gap in diagnostic access limits timely…
ISEF · 2026
Biomedical Engineering
Observing the mobility difficulties faced by wheelchair users, it becomes evident that the wheelchair model is often inadequate in relation to the daily environment and the accessibility nee…
ISEF · 2026
Biomedical Engineering
Hemorrhagic stroke occurs when a cerebral blood vessel ruptures, creating an urgent need for intervention to prevent fatality. Developing a neuroprotectant designed to form a synthetic barri…
ISEF · 2026
Biomedical Engineering
Modern High-Throughput Screening (HTS) is a system used in drug discovery labs that can rapidly test hundreds of thousands of chemicals against a target in a disease with the aim of developi…
ISEF · 2026
Biomedical Engineering
Partial-thickness burns make up 85.4% of all clinical cases (Ji et al., 2024). At the same time, those in underrepresented areas display higher burn incidences and are less likely to adminis…
ISEF · 2026
Biomedical Engineering
Obstructive and restrictive respiratory diseases are major global health challenges and are associated with prolonged exposure to smoke and air pollution. Among these conditions, Chronic Obs…
ISEF · 2026
Biomedical Engineering
symptoms of childhood Attention-Deficit/Hyperactivity Disorder (ADHD) may lead to socioeconomic consequences in adulthood, including long-term unemployment. Access to traditional clinical ca…
ISEF · 2026
Biomedical Engineering
Purpose or Problem: Millions of people suffer from stammering, and adult severe stammering patients have a low chance of recovery. Other temporary alleviation methods are not consistent or a…
ISEF · 2026
Biomedical Engineering
Primary liver cancer is a leading cause of cancer-related deaths worldwide. However, one of its standard treatments, transarterial chemoembolization (TACE), often has low target vessel speci…
ISEF · 2026
Biomedical Engineering
Tympanic membrane perforations affect over 320 million people worldwide and are a large cause of preventable hearing loss. Current procedures rely on manual skill, limited visualization of t…
ISEF · 2026
Biomedical Engineering
Bleeding poses as the most serious cause of death in traumatic injury. Whenever someone is bleeding from one of their limbs, a tourniquet (TQ) is vital for stopping hemorrhage. TQs work by t…
ISEF · 2026
Biomedical Engineering
This is a new direction in the development of athlete health monitoring and the analysis of performance in relation to maximum capacity. A crucial and important aspect in both amateur and pr…
ISEF · 2026
Biomedical Engineering
Diaphragm dysfunction is a major cause of respiratory failure, affecting millions of patients worldwide. Current assistive solutions rely on invasive approaches with high complication rates,…
ISEF · 2026
Biomedical Engineering
Peripheral neuropathy is a progressive condition that reduces sensation in the feet, leading to impaired balance, altered plantar pressure distribution, and increased risk of falls or injuri…
ISEF · 2026
Biomedical Engineering
Ultrasound(US)-guided vascular access requires a high level of expertise as the clinician must understand the spatial relationship between US probe, imaging, and the patient’s anatomy. Furth…
ISEF · 2026
Biomedical Engineering
Background: Parkinson's Disease significantly impairs quality of life through motor deficits like tremors. Current pharmacological treatments often carry side effects, while physical therapy…
ISEF · 2026
Biomedical Engineering
Decellularization is essential for producing extracellular matrix (ECM) scaffolds used in regenerative medicine. Conventional detergent-based methods can achieve effective cell removal but o…
ISEF · 2026
Biomedical Engineering
The global incidence of Inflammatory Bowel Disease (IBD) is on a continuous rise. Probiotic therapy has emerged as a research hotspot due to its synergistic advantages in "regulating intesti…
ISEF · 2026
Biomedical Engineering
Optogenetics leverages genetically encoded, light-sensitive proteins to achieve high spatiotemporal resolution in cellular regulation. However, current chimeric proteins suffer from slow swi…
ISEF · 2026
Biomedical Engineering
Over 2 million Americans and countless others around the world suffer from type 1 diabetes which is an incurable health condition where the pancreas stops making essential hormones called in…
ISEF · 2026
Biomedical Engineering
This project involved designing and testing a lower-limb exoskeleton integrated with a brain-computer interface (BCI). Its objective was to address the physiological, psychological, and soci…
ISEF · 2026
Biomedical Engineering
Globally, a limb is amputated every 20 seconds due to complications from diabetes. Over 18 million people suffer from chronic diabetic wounds, caused by impaired circulation and reduced woun…
ISEF · 2026
Biomedical Engineering
Early disease diagnostics rely primarily on biochemical reactions requiring centralized laboratories or significant processing time. However, malignant transformation alters the electrical p…