Cellular and Molecular Biology
The purpose of this experiment is to see if changing the chemical structure of Methylbutenol (MBO) synthase’s active site from a Phenylalanine to a Tyrosine will effect the production of MBO…
Product Science (Biological) (Junior Division Only)
Honorable_mention Award
Objectives/Goals The objective and goal of my experiment is to see which ant-oxidant will prevent an apple from turning brown the longest. I want to see which anti-oxidants are effective in…
Cellular and Molecular Biology
Tissues in our body experience a variety of mechanical stimuli that are important in physiological and pathophysiological conditions. Compression can arise from cells in the stiff micro envi…
Biochemistry/ Molecular Biology
Objectives/Goals Studies say that the isoflavones cause an increase of cellular proliferation while other studies disagree and conclude that the isoflavones either have no effect on the grow…
Cellular and Molecular Biology
The purpose of my project was to determine if administering tocotrienol with a form of chemotherapy will induce apoptosis at a faster rate. The way I conducted this experiment was that I acq…
Biochemistry/ Molecular Biology
Honorable_mention Award
Objectives/Goals The objective of this experiment is to determine if ,tocotrienol, an antioxidant, will induce apoptosis. This experiment analyzed the apoptotic effects of tocotrienol on par…
Biochemistry/ Molecular Biology
Objectives/Goals The purpose of my project was to determine if exposing heavy cream to UV light would be a method of producing cholecalciferol, also known as vitamin D3. Methods/Materials My…
Cellular and Molecular Biology
Type 2 diabetes rates are on the rise due to changing lifestyles. Diabetes can cause hyperglycemic events, which can damage cells. However, how hyperglycemic damage occurs is not completely…
Biochemistry/ Molecular Biology
Objectives/Goals This study was undertaken to prove that hypothermic conditions can be an in-vitro model of the tau hyperphosphorylation seen in Alzheimer's disease. Secondly, this study was…
Cellular and Molecular Biology
Western diet has been linked with health issues, such as obesity and Alzheimer’s disease. It is vital to understand the mechanisms in which diet affects the brain in order to identify therap…
Product Science (Biological) (Junior Division Only)
Objectives/Goals For my science fair project I tested three household objects (TV remote, house phone and game controller) first with hand sanitizer and a week later with antibacterial soap…
Cellular and Molecular Biology
G protein coupled receptors (GPCR’s) are the largest family of membrane bound receptors. They are characterized by seven transmembrane helices. NBA1, a generic gene identifier, will be used…
Biochemistry/ Molecular Biology
First Award
Objectives/Goals To study the molecular mechanisms of cartilage regeneration. Specifically, I am interested to model a medical treatment called prolotherapy, in which a physician injects a p…
Cellular and Molecular Biology
Harnessing the immune system to attack cancer is a novel treatment called immunotherapy. It uses antibodies to block signaling pathways that deactivate T cells. These inhibitory pathways exi…
Product Science (Biological) (Junior Division Only)
Objectives/Goals The purpose of this project was to investigate if the traditional over-the-counter painkillers affect the stomach acid and health of an individual in the future. Over-the-co…
Cellular and Molecular Biology (inferred)
Molybdenum is an essential trace element. In biological systems it exists as Molybdenum Cofactor (MoCo), the synthesis of which is performed by Gephyrin. Mutations in human Gephyrin lead to…
Cellular and Molecular Biology
Neuroblastoma is a lethal and commonly metastatic childhood cancer that arises when neural crest cells fail to differentiate properly during embryonic development. A group of cell-signaling…
Product Science (Biological) (Junior Division Only)
Honorable_mention Award
Objectives/Goals The objective of this experiment was to determine which moisturizer performs the best in keeping skin moist. Methods/Materials I tested 5 different moisturizers three times…
Cellular and Molecular Biology
Imatinib is a drug commonly used for the treatment of BCR-ABL1-positive leukemia. However, imatinib-resistant cells often develop after treatment, causing therapeutic failure. My previous re…
Biochemistry/ Molecular Biology
Objectives/Goals In 2017 alone, over 8 million people around the world will die of cardiac diseases, most often induced by myocardial infarctions (MIs). Current treatment options, including…
Cellular and Molecular Biology
Angiogenesis, the formation of new blood vessels, is key in wound healing, embryonic development, and survival of cancerous tumors. Vascular Endothelial Growth Factor (VEGF) and its binding…
Cellular and Molecular Biology
There is a need for a clinical alternative for the "gold standard" autograft. An autograft involves harvesting tissue from alternate locations in the body and substituting tissue in lacking…
Cellular and Molecular Biology
Genome sequencing, the future of bacterial medicine. My name is Josh Proehl and I used genome sequencing to find a natural probiotic to replace the use of low dose growth antibiotics in turk…
Cellular and Molecular Biology
Platelet endocytosis is very important, especially for fibrinogen uptake. Platelets contain several integral membrane proteins called soluble N-ethylmaleimide-sensitive factor Attachment Pro…
Product Science (Biological) (Junior Division Only)
Honorable_mention Award
Objectives/Goals The objective of this project was to find the most effective treatment against acne. In my hypothesis I stated, if I use acne treatments with either benzoyl peroxide, salicy…