38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2018
Cellular and Molecular Biology
Environmental exposures can impact the expression of genes via epigenome, which is transgenerationally inherited. Short term exposure to unfavorable conditions could permanently alter the ex…
CSEF · 2018
Biochemistry/ Molecular Biology First Award
Objectives/Goals Our goal was to determine whether there is a significant difference in element composition between metastatic and non-metastatic breast cancer cells through the use of X-Ray…
ISEF · 2018
Cellular and Molecular Biology
Background Breast cancer, the most common cancer in women results in 40,000 deaths annually. Different breast cancer subsets are defined based on the expression of specific receptors: estrog…
CSEF · 2018
Biochemistry/ Molecular Biology Second Award
Objectives/Goals The objective of this study is to determine the ratio of how genes are passed on and how often they physically appear in the offspring. Methods/Materials Wild type male C. e…
CSEF · 2018
Product Science (Biological) (Junior Division Only)
Objectives/Goals The objective of this experiment is to determine if a $50 ultra violet wand is more effective at disinfecting surfaces than 409 and Lysol. Methods/Materials Cleanwave UV Wan…
ISEF · 2018
Cellular and Molecular Biology
In neurodegenerative diseases such Parkinson’s disease (PD), the misfolding and deposition of proteins a-synuclein and tau is hallmark. Conformational changes in native unfolded proteins, ta…
ISEF · 2018
Cellular and Molecular Biology
Malignant melanoma is characterized by its ability to metastasize, and is responsible for 90% of skin cancer mortality. Metastasis requires cell migration from a primary tumor to blood and l…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals Alzheimer's Disease (AD) is the leading cause of dementia and memory loss in adults. The disease presents itself through cognitive impairment. Dementia, memory loss, buildup…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this experiment was to identify changepoints in gene expression in the aging human brain and determine their role in the late onset of neurodegenerative dis…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals In today's world, many instances of alcohol abuse and engagement are common and evident. There are various consequences of this behavior, ranging from a hangover the next da…
CSEF · 2018
Biochemistry/ Molecular Biology First Award
Objectives/Goals My objective is to find the type of rice with the lowest amount of starch for people who have diabetes. Methods/Materials Materials- Pressure cooker, jasmine rice, basmati r…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals Current gene constructs need an effective mechanism able to maintain expression units in open chromatin configuration, both prohibiting cross talk between nearby promoters i…
CSEF · 2018
Product Science (Biological) (Junior Division Only) Third Award
Objectives/Goals After noticing differences in my glucose meter readings I was worried about their accuracy, so I chose to test blood glucose meter accuracy. My hypothesis was that blood glu…
ISEF · 2018
Cellular and Molecular Biology
Oxidative damage in the genome occurs when reactive oxygen species (ROS), a byproduct of metabolism or from exogenous sources, come in contact with DNA. This has been suggested to play a rol…
ISEF · 2018
Cellular and Molecular Biology
Gliomas are primary malignant tumors of brain and spinal cord with low survival without effective therapies. Annexin A1 (ANXA1) is a protein, which participates in proliferation, immune resp…
ISEF · 2018
Cellular and Molecular Biology
The overuse of antimicrobials in many aspects of daily life has ushered in a wave of antimicrobial resistance to antibiotics that have been effective for decades. Resistance to antibiotics i…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals Normally, the presence of Huntington's disease (HD) is marked by an aggregation (inclusion) of the diseased huntingtin protein, which is visible via standard electron micros…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals Bisphenol A (BPA) is a plastic monomer used in nearly every form of plastic packaging. BPA is known to be an estrogen disruptor and imitator, which has massive potential imp…
ISEF · 2018
Cellular and Molecular Biology
Nearly one in eight deliveries in the United States is preterm. Preterm birth has been correlated with oxidative stress, damage caused to cells by free radicals, in the uterine myometrium. O…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals The objective of this study was to measure the content of Vitamin C in different conditions of fruits (dried, canned, and fresh) and determine which had the greatest content…
ISEF · 2018
Cellular and Molecular Biology
The objective of this project was to characterize gal-7 as an antibiotic. The purpose of this research was to identify a model for glycan-specific antibiotics capable of reducing the risk of…
ISEF · 2018
Cellular and Molecular Biology
Irreparable DNA lesions caused by radiation therapy induce apoptosis, a suicidal response that occurs in both cancerous and normal cells. Remarkably, mouse and human tissues in experiments t…
ISEF · 2018
Cellular and Molecular Biology Third Award
At first glance, diabetic kidney disease and cancer may seem to have little in common besides sharing high mortality rates. Diabetic kidney disease is a condition in which increased glucose…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals The objective of my project was to determine the effect of the FGFR tyrosine kinase inhibitor AZD4547 on cell proliferation, induced apoptosis, and activated pathways in neu…
CSEF · 2018
Product Science (Biological) (Junior Division Only) Honorable_mention Award
Objectives/Goals Our project is to discover how to delay the decaying rate of a double reed? Double reeds, belonging to the bassoon and oboe, are delicate, short term lasting mouth pieces th…
ISEF · 2018
Cellular and Molecular Biology
GATA4 is a transcription factor critical in the developmental process and early differentiation of the gastrointestinal tract. Studies using genetically modified mouse models have shown GATA…
ISEF · 2018
Cellular and Molecular Biology
Human induced pluripotent stem cells (hiPSC) have a huge potential use in regenerative medicine. However, the mutant frequency of hiPSC reaches the level of differentiated cells rather than…
ISEF · 2018
Cellular and Molecular Biology Third Award
Metastatic breast cancer affects more than 250,000 people every year. Interactions of SOX transcription factors (TFs) and MALAT1 lncRNA may induce breast cancer metastasis. This study’s purp…
CSEF · 2018
Biochemistry/ Molecular Biology
Objectives/Goals The purpose of the study was to analyze the sequence and structure conservation and identity of the vision protein, rhodopsin, across multiple species of ectothermic and end…
ISEF · 2018
Cellular and Molecular Biology
Mechanisms involved in neuromuscular junction (NMJ) morphogenesis and active zone (AZ)-GluR receptor alignment are an active field of research in Drosophila neuroscience. I investigated four…