Browse real student projects, abstracts, and awards.
ISEF · 2018
Cellular and Molecular Biology
In recent studies, scientists found that cancer is highly associated with inflammation and, macrophages, which play an important role in inflammatory response, is found to be interfered by t…
ISEF · 2018
Cellular and Molecular Biology
Low birth weight (LBW) offspring have a high risk of developing cardiovascular and renal diseases such as chronic kidney disease and hypertension, which have no preventative measures or cure…
ISEF · 2018
Cellular and Molecular Biology
Environmental exposures can impact the expression of genes via epigenome, which is transgenerationally inherited. Short term exposure to unfavorable conditions could permanently alter the ex…
ISEF · 2018
Cellular and Molecular Biology
Background Breast cancer, the most common cancer in women results in 40,000 deaths annually. Different breast cancer subsets are defined based on the expression of specific receptors: estrog…
ISEF · 2018
Cellular and Molecular Biology
In neurodegenerative diseases such Parkinson’s disease (PD), the misfolding and deposition of proteins a-synuclein and tau is hallmark. Conformational changes in native unfolded proteins, ta…
ISEF · 2018
Cellular and Molecular Biology
Malignant melanoma is characterized by its ability to metastasize, and is responsible for 90% of skin cancer mortality. Metastasis requires cell migration from a primary tumor to blood and l…
ISEF · 2018
Cellular and Molecular Biology
Oxidative damage in the genome occurs when reactive oxygen species (ROS), a byproduct of metabolism or from exogenous sources, come in contact with DNA. This has been suggested to play a rol…
ISEF · 2018
Cellular and Molecular Biology
Gliomas are primary malignant tumors of brain and spinal cord with low survival without effective therapies. Annexin A1 (ANXA1) is a protein, which participates in proliferation, immune resp…
ISEF · 2018
Cellular and Molecular Biology
The overuse of antimicrobials in many aspects of daily life has ushered in a wave of antimicrobial resistance to antibiotics that have been effective for decades. Resistance to antibiotics i…
ISEF · 2018
Cellular and Molecular Biology
Nearly one in eight deliveries in the United States is preterm. Preterm birth has been correlated with oxidative stress, damage caused to cells by free radicals, in the uterine myometrium. O…
ISEF · 2018
Cellular and Molecular Biology
The objective of this project was to characterize gal-7 as an antibiotic. The purpose of this research was to identify a model for glycan-specific antibiotics capable of reducing the risk of…
ISEF · 2018
Cellular and Molecular Biology
Irreparable DNA lesions caused by radiation therapy induce apoptosis, a suicidal response that occurs in both cancerous and normal cells. Remarkably, mouse and human tissues in experiments t…
ISEF · 2018
Cellular and Molecular Biology Third Award
At first glance, diabetic kidney disease and cancer may seem to have little in common besides sharing high mortality rates. Diabetic kidney disease is a condition in which increased glucose…
ISEF · 2018
Cellular and Molecular Biology
GATA4 is a transcription factor critical in the developmental process and early differentiation of the gastrointestinal tract. Studies using genetically modified mouse models have shown GATA…
ISEF · 2018
Cellular and Molecular Biology
Human induced pluripotent stem cells (hiPSC) have a huge potential use in regenerative medicine. However, the mutant frequency of hiPSC reaches the level of differentiated cells rather than…
ISEF · 2018
Cellular and Molecular Biology Third Award
Metastatic breast cancer affects more than 250,000 people every year. Interactions of SOX transcription factors (TFs) and MALAT1 lncRNA may induce breast cancer metastasis. This study’s purp…
ISEF · 2018
Cellular and Molecular Biology
Mechanisms involved in neuromuscular junction (NMJ) morphogenesis and active zone (AZ)-GluR receptor alignment are an active field of research in Drosophila neuroscience. I investigated four…
ISEF · 2018
Cellular and Molecular Biology Fourth Award
Abscission is the final stage of cytokinesis, the division of the cytoplasm between daughter cells, in which cells are physically separated by severing the intercellular bridge on either sid…
ISEF · 2018
Cellular and Molecular Biology
The purpose of this project is to detect DNA damaging effect caused by various Aloe Vera extracts. A total of four Aloe Vera extract samples were tested using the Comet Assay. Three samples…
ISEF · 2018
Cellular and Molecular Biology
The purpose of this experiment is to determine if HisKPC-3 mutated beta-lactamase proteins are more antibiotic resistant than HisKPC-2 proteins, and what is occurring at a molecular level th…
ISEF · 2018
Cellular and Molecular Biology Fourth Award
Aquaporin1a1 is an integral membrane protein that facilitates the transportation of water molecules across a cell. Previous research showed that morpholino knockdowns showed reduced transfer…
ISEF · 2018
Cellular and Molecular Biology
Natural killer (NK) cells are an important subset of immune cells in anti-tumor immunity; however, much is still unknown about what mechanisms activate NK cells and make them more efficient…
ISEF · 2018
Cellular and Molecular Biology
In most perennials, the flowering process is prolonged due to the extensive growth period, causing time gaps in plant research and cultivation. The purpose of the study is to assess the effi…
ISEF · 2018
Cellular and Molecular Biology Second Award
It is evident that the tongue perceives tactile sensation, but little is known about the neurons that mediate this. Since tropomyosin receptor kinase C (TrkC) neurons are mechanosensory in s…
ISEF · 2018
Cellular and Molecular Biology Fourth Award
Lupine flour is a novel food ingredient derived from the endosperm of lupine beans and is increasing in popularity, primarily in Europe and Australia. Peanut allergy is the leading cause of…
ISEF · 2018
Cellular and Molecular Biology
The purpose of this research is to create a new non-intrusive allergy test, that is less expensive, more time efficient, and can provide an alternative for not only the general majority of p…
ISEF · 2018
Cellular and Molecular Biology
Purpose of the Experiment X chromosome inactivation (XCI) is an essential epigenetic silencing process established during early embryonic development of female mammals, guaranteeing a proper…
ISEF · 2017
Cellular and Molecular Biology
Parkinson’s disease (PD) is an incurable, progressive neurodegenerative disorder characterized by the intracellular accumulation of alpha-synuclein (aSyn). aSyn oligomers have been implicate…
ISEF · 2017
Cellular and Molecular Biology
Mucociliary clearance of toxins from the respiratory tract epithelium depends on a precise ratio of ciliated to goblet cells. If this ratio is low, mucus produced by the goblet cells builds…
ISEF · 2017
Cellular and Molecular Biology
In vitro fertilization (IVF) involves a complex series of clinical and laboratory procedures with the goal of conceiving a healthy child for infertile couples. The high frequency of chromoso…