38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2026
Robotics and Intelligent Machines Third Award
Large language models (LLMs) are increasingly trusted in domains such as education, research, and decision making. Despite their widespread adoption, fundamental questions remain about align…
ISEF · 2026
Cellular and Molecular Biology Third Award
KARS1 encodes bifunctional cytoplasmic and mitochondrial lysyl-tRNA synthetases, and biallelic loss-of-function variants cause infantile-onset progressive leukoencephalopathy (LEPID) and rel…
ISEF · 2026
Cellular and Molecular Biology Third Award
Ischemic injury causes neuronal loss and neurological deficits, challenging stroke recovery. After injury, a glial scar forms, but its regulation of neural stem cell (NSC) fate remains uncle…
ISEF · 2026
Biomedical Engineering Third Award
Major challenges exist in detecting infectious diseases early on as biomarker concentrations are often below the limit of detection (LoD) of conventional assays. This detection failure leads…
ISEF · 2026
Embedded Systems Third Award
Falls are the second leading cause of unintentional injury death worldwide, responsible for over 684,000 deaths annually. Existing solutions leave critical gaps. Preventive approaches like s…
ISEF · 2026
Physics and Astronomy Third Award
Current drug design methods treat proteins as rigid structures, failing to capture functional high-energy states. This contributes to 40–50% of clinical-stage drug failures. Mapping continuo…
ISEF · 2026
Translational Medical Science Third Award
Breast cancer recurrence rates reach up to 50%, yet existing clinical tools rely on single modality data or repeated medical check-ups. My model, OncoTwin, is a novel recurrence-risk predict…
ISEF · 2026
Plant Sciences Third Award
Orchids are plants with challenging propagation; therefore, in vitro cultivation is a viable alternative for seedling production, despite its high cost. Additionally, growth is slow, and the…
ISEF · 2026
Biomedical Engineering Third Award
Nearly half of the world's population, 47%, has little to no access to diagnostic testing, which can delay care until conditions become critical. This gap in diagnostic access limits timely…
ISEF · 2026
Biomedical and Health Sciences Third Award
Fibromyalgia is a chronic disorder characterized by widespread pain, fatigue, and cognitive impairments. Current treatments primarily target symptoms rather than underlying pathology. Growin…
ISEF · 2026
Materials Science Third Award
Reducing carbon emissions in modern engineering has a critical tradeoff: materials must be lightweight to improve energy efficiency, yet strong enough to maintain structural integrity. Polye…
ISEF · 2026
Environmental Engineering Third Award
An estimated 92 million tons of textiles are discarded annually, yet fabric-to-fabric recycling accounts for less than 1% of production due to quality degradation and financial barriers. Thi…
ISEF · 2026
Biomedical and Health Sciences Third Award
Glioblastoma (GBM) is the most common malignant brain cancer in adults, and patient survival still remains low. However, 83% of GBM cases have Telomerase Reverse Transcriptase promoter (TERT…
ISEF · 2026
Biochemistry Third Award
Glioblastoma (GBM) is the most aggressive primary brain tumor. It is associated with poor survival and frequent development of resistance to the first-line chemotherapeutic agent temozolomid…
ISEF · 2026
Embedded Systems Third Award
Wilderness search-and-rescue (SAR) operations across U.S. national parks exceed 4,000 to 4,500 incidents annually, with over 40,000 missions between 2015 and 2025. In August 2024, a multi-da…
ISEF · 2026
Biomedical Engineering Third Award
Obstructive and restrictive respiratory diseases are major global health challenges and are associated with prolonged exposure to smoke and air pollution. Among these conditions, Chronic Obs…
ISEF · 2026
Robotics and Intelligent Machines Third Award
Autonomous drone research has become increasingly important, yet there are many burdens which make its access limited. Especially for autonomous drone racing, high-end motion-capture systems…
ISEF · 2026
Biomedical Engineering Third Award
Purpose or Problem: Millions of people suffer from stammering, and adult severe stammering patients have a low chance of recovery. Other temporary alleviation methods are not consistent or a…
ISEF · 2026
Earth and Environmental Sciences Third Award
The eastern oyster is critical for coastal habitats and provides biological benefits such as improved water quality, stabilization of shorelines, and increased estuarine biodiversity, yet oy…
ISEF · 2026
Behavioral and Social Sciences Third Award
Sustained attention span is declining among adolescents, linked to weakened memory and reading comprehension, a significant barrier to academic/social success. This study tested and develope…
ISEF · 2026
Robotics and Intelligent Machines Third Award
Globally, 43 million blind and 295 million visually impaired individuals lack independent indoor mobility. Existing aids are either reactive (white canes), expensive (guide dogs), or ineffec…
ISEF · 2026
Computational Biology and Bioinformatics Third Award
The incurable nature of Amyotrophic Lateral Sclerosis (ALS) is compounded by a diagnostic lag, where symptoms emerge only after irreversible motor neuron attrition. Rather than viewing ALS s…
ISEF · 2026
Computational Biology and Bioinformatics Third Award
Whole-slide histopathology images(WSIs) form the backbone of AI development in cancer research. However, their high curation cost, gigapixel complexity, and limited availability across insti…
ISEF · 2026
Energy: Sustainable Materials and Design Third Award
When cables and wired power delivery present safety or practicality issues, such as in biomedical implants or robotics applications, Wireless Power Transfer (WPT) using metamaterials (engine…
ISEF · 2026
Environmental Engineering Third Award
Marine oil spills release toxic polycyclic aromatic hydrocarbons and other compounds that harm organisms and bioaccumulate across food chains. Meanwhile, conventional remediation primarily r…
ISEF · 2026
Technology Enhances the Arts Third Award
While technology has revolutionised music education, visually impaired musicians remain marginalised due to the visual-centric design of existing practice platforms. To restore artistic inde…
ISEF · 2026
Chemistry Third Award
Accurate and rapid analysis of amino acids is essential for metabolomics and disease related biomarker studies. 19F NMR spectroscopy offers high sensitivity and no biological background sign…
ISEF · 2026
Chemistry Third Award
In this project, uniform Sized SPIONs of various sizes were synthesized in a reverse micelles system under aerial conditions. The variation in size was achieved by varying the loading of iro…
ISEF · 2026
Energy: Sustainable Materials and Design Third Award
Electrochemical seawater splitting is one of the most promising methods for sustainable hydrogen production. However, its major challenge is the simultaneous chlorine evolution reaction (CER…
ISEF · 2026
Software Design Third Award
Soil degradation affects over 1.7 billion people globally, yet long-term prediction of soil evolution remains fundamentally challenging because soil emerges from complex interactions among c…