Biochemistry
Third Award
In order to prevent blood clots in severe COVID-19 cases, a highly selective and sensitive biosensor capable of quantifying trace levels of thrombin using the combination of a single strande…
Behavioral and Social Sciences
Third Award
In the past decade, the US government and other key interest groups have taken serious steps to address the addiction epidemic; however, despite these efforts, asper the data from the Nation…
Robotics and Intelligent Machines
Third Award
Glaucoma is the second leading cause of blindness, responsible for 15% percent of the total world blindness. It is a chronic eye disease that damages the optic nerve and causes irreversible…
Translational Medical Science
Third Award
Parkinson’s disease (PD) is the leading cause of disability worldwide. Indeed, PD cases are rapidly rising, especially in underdeveloped areas that don’t have ready access to therapeutic car…
Chemistry
Third Award
The purpose of this research is selective synthesis of indirubins and analysis of their properties. First, the synthesis of indirubins was carried out using potassium indoxyl sulfate which h…
Biomedical Engineering
Third Award
Color Vision Deficiency is the most common genetic disability, affecting over 400 million people in the world, and currently has no cure. There are attempts to mitigate the effect of color v…
Animal Sciences
Third Award
Of the original 11 native forest bird species known from the island of O?ahu in the Hawaiian island chain, only 3 remain today. They are the O?ahu ?Amakihi (Chlorodrepanis flava), ?Apapane (…
Computational Biology and Bioinformatics
Third Award
The cocktail party problem renders conversation difficult for hard-of-hearing individuals in multi-speaker environments. Current hearing aids cannot amplify the primary speaker's voice alone…
Embedded Systems
Third Award
Many critical systems, including financial, banking, telecom and nuclear weapons, rely on the Global Positioning System (GPS) for synchronization of clocks that is essential for their operat…
Plant Sciences
Third Award
Harvesting Limulus polyphemus (horseshoe crabs) to produce the Limulus amoebocyte lysate endotoxin assay for medical devices, pharmaceuticals, and drinking water is ravaging coastal ecosyste…
Computational Biology and Bioinformatics
Third Award
Scoliosis is a condition of abnormal spinal curvature with approximately 60,000 U.S. pediatric patients undergoing surgery or being placed into braces each year. Skeletal maturity assessment…
Robotics and Intelligent Machines
Third Award
Breast cancer is the second-leading cause of cancer-related deaths in women globally. Advanced diagnosis of intrinsic molecular subtype is key to evaluating intermediate survival; however, b…
Physics and Astronomy
Third Award
Much of the exoplanet transit data from the Kepler space telescope remains unanalyzed, especially in the search for habitability. To enable the investigation of Kepler exoplanets without the…
Behavioral and Social Sciences
Third Award
The number of youths affected with mental health disorders has increased throughout the years. 41% of adolescents with anxiety do not have access to mental health services, so it is importan…
Biomedical Engineering
Third Award
Current upper limb prostheses lack effective and intuitive control systems and are often exorbitantly expensive. As a result, while prosthesis use can significantly increase quality of life,…
Chemistry
Third Award
The photo-responsive fluorescence behaviors (Photomechanofluorochromism and the Photomechanical effect) of a pentiptycene-anthracene hybrid system substituted with a semifluorinated alkoxy c…
Physics and Astronomy
Third Award
The effects of wide binary star systems on the formation and evolution of exoplanets are relatively unknown. A large portion of exoplanets reside in wide binary systems, so fully understandi…
Biochemistry
Third Award
Proton nuclear magnetic resonance (1H-NMR) spectroscopy is commonly used in metabolomics studies involving the quantitation of complex bio-fluids and mixtures to correlate metabolic changes…
Earth and Environmental Sciences
Third Award
Antibiotic pollution in soils and groundwater is one of the world’s most pressing problems. There are 1.4µg of antibiotics per-liter of freshwater and 125,000 tons of antibiotics polluted ev…
Environmental Engineering
Third Award
Contaminated water is responsible for causing millions of deaths and various effects in people’s health worldwide. Many countries spend billions of dollars to fix this problem. Therefore, th…
Robotics and Intelligent Machines
Third Award
Breast cancer is the leading cause of cancer deaths among women worldwide, but early detection and diagnosis can significantly improve a patient’s prognosis. Conventionally, biopsy breast ti…
Biomedical Engineering
Third Award
Designing synthetic genes for heterologous expression is a keystone of biotechnology. In protein sequences—as there are 61 sense codons but only 20 standard amino acids—most amino acids are…
Microbiology
Third Award
Helicobacter pylori is a gram-negative bacterium responsible for multiple gastrointestinal diseases, including gastritis, peptic ulcer, gastric carcinoma and lymphoma. About 2/3 of the world…
Robotics and Intelligent Machines
Third Award
Collectively, around 4.1 million tons of pesticides are applied to crops annually, but less than 0.1% is absorbed by target plants, with residue transmitted well out of intended areas into d…
Microbiology
Third Award
Currently, more than 800 million are food insecure. While chemical growth promoters are widely used to enhance crop production, they have caused serious environmental pollution and adverse h…
Biomedical and Health Sciences
Third Award
Neuroblastoma is one of the most common malignant pediatric tumors, accounting for 10% of all childhood cancer deaths. However, current treatment methods often involve chemotherapeutic agent…
Physics and Astronomy
Third Award
Observations of the rotation of pulsars, highly magnetized rotating neutron stars, have revealed a mysterious type of rotation anomaly: glitches, discontinuous events where the pulsar sudden…
Computational Biology and Bioinformatics
Third Award
Despite major advances in immunosuppression, thousands of transplanted organs are still rejected, endangering the lives of many patients. Traditional approaches to understanding transplant r…
Earth and Environmental Sciences
Third Award
The protection zones or capture zones of springs in a desert environment can be hard to identify, but they are critically important for spring protection. Most springs fed by regional aquife…
Earth and Environmental Sciences
Third Award
The purpose of this experiment was to determine efficacy of lab-engineered pesticide resistant D. pulex as environmental buffers against the effects of malathion on H. littoralis. Pesticide…