Search past science fair projects

Development and in vitro Verification of a Polymersome for Blood-Brain Barrier Transport Through a Novel Machine Learning Model

Translational Medical Science Second Award

Across neurological drug development, researchers struggle with the inability of most drugs to pass through the blood-brain barrier (BBB), due to the semipermeable membrane’s high selectivit…

Development of a Photocaged Cathepsin B Inhibitor With Increased Lysosome Uptake and Light-activated Biological Functions

Chemistry Second Award

Cathepsin B in lysosome is a cysteine protease that plays an important role in various pathological processes including many cancers. Therefore, it is a cancer protein biomarker. A method to…

Development of a Solar Powered Buoy to Measure and Report the Pollution Level of Wetlands

Environmental Engineering Second Award

Environmental pollution, which is one of the main causes of global warming, may have variations within itself; however, water, which is at the point of all cycles in nature, a blanket coveri…

Discovery of New Extragalactic Planet Candidates: A Novel End-to-End Machine Learning Pipeline for Efficient Transit Detection in the X-ray Spectrum

Physics and Astronomy Second Award

The discovery of M51-ULS-1b, the only extragalactic planet orbiting an X-ray Source (XRS), unveiled a gap in our current understanding of planetary formation and evolution. How this planet f…

Documenting Native Fauna in an Aquatic Suburban Setting

Zoology Second Award

Easy AED: An Autonomous VTOL Emergency Equipment Delivery Drone System

Robotics and Intelligent Machines Second Award

Every year, six million people die from cardiac arrest in the world with 436,000 victims in the United States alone. This problem is made worse because, in many counties, more than 50% of pe…

Ecofriendly Design and Fabrication of a Microalgae-Based Sponge to Efficiently Remove Oil From Water for Environmental Remediation

Earth and Environmental Sciences Second Award

Oil spills continue to affect millions of families yearly. Significant research has gone into the development of both organic and inorganic solvents. However, the issue with these sorbents i…

Effect of the Apex Angle of a Triangular-Shaped Vibrating Structure on Acoustic Streaming

Physics and Astronomy Second Award

Acoustic streaming (AS) is generated by an acoustic field in a fluid and is capable of creating a specific flow pattern and a jet. We investigated the characteristics of AS produced by the v…

Elucidating RSV-Host Protein-Protein Interactions: Novel implementation of Graph Attention Networks (GAT) and Structural Visualization

Computational Biology and Bioinformatics Second Award

Respiratory Syncytial Virus (RSV) poses significant health risks, especially to infants under six months and adults over 65. The objective of this study is to deepen the understanding of str…

ERPD: A Novel Protein Design Approach to Engineering and Optimizing Smaller Fluorescent Proteins

Biochemistry Second Award

Green fluorescent proteins (GFP) are used as markers to image ß-amyloid plaques in Alzheimer's diagnosis, visualize cancer progression, and measure drug toxicity. However, the large size of…

Extents of Marine Salinization Increasing Thermal Tolerance in Seagrass

Plant Sciences Second Award

To address the depletion of seagrass, this study aimed to understand seagrass conservation approaches by investigating the impact of varying salinity levels and temperature fluctuations on t…

FISQ: A Few-Shot, Interpretable, and Self-Supervised Quantum Machine Learning Approach to Automated Real-Time Prediction Over Multiple Domains

Robotics and Intelligent Machines Second Award

To ascertain complex relationships between inputs and outputs and function at high accuracies, Machine Learning algorithms require vast amounts of high-quality data. In many instances, the q…

Forecasting Domoic Acid Levels From Harmful Algal Blooms Along the Pacific Northwest Coast

Earth and Environmental Sciences Second Award

Here is the edited version: In spring 2015, the U.S. Pacific Coast experienced an unprecedented surge in domoic acid concentrations, exceeding federal safety limits by over 700% in some part…

FRESH Bioprinting-Based Synthesis and Biomechanical Characterization of Tissue Engineered Vascular Grafts

Biomedical Engineering Second Award

Cardiovascular disease (CVD) is the leading cause of global death, and Coronary Artery Disease (CAD) is its most common manifestation. Restoring perfusion to myocardial tissue in CAD often n…

From Crown to Current Year III: Engineering Cellulosic Fiber-Based Battery Cells - A Safe and Scalable Alternative to Lithium Technology

Chemistry Second Award

Steadfast technological advancements have driven notable growth in the demand for efficient and affordable power sources, with production of the lithium-ion battery surging nearly 700% in th…

Gaze Link: A Multi-language Low-Cost Mobile Eye-Gesture Communication System With Large Language Models for People With Amyotrophic Lateral Sclerosis

Systems Software Second Award

People with Amyotrophic Lateral Sclerosis (PALS), who have severe motor and speech impairments, mostly rely on their eyes and assistive technology to communicate. However, existing high-tech…

GLOBAL WARMING MITIGATION: OPTIMIZING CO2 REMOVAL OF ALGAE FARMING

Environmental Engineering #2 Second Award

HAGU: AI-Generated Harmonically Rich Classical Guitar Pieces

Technology Enhances the Arts Second Award

Current symbolic music generation models and music modeling techniques primarily rely on language models designed for language modeling. Most of these models treat musical features (e.g. pit…

Harnessing the Signalosome to Enhance Ex-Vivo Generation of Tumor Antigen-Specific T Cells

Cellular and Molecular Biology Second Award

The adoptive transfer of tumor antigen-specific T cells (ASTs) can serve as an effective immunotherapy against pediatric solid tumors of the central nervous system (CNS). However, current me…

Human Milk Immune Complexes Isolated Following Pregnancies Complicated by COVID-19 Infection Contain SARS-CoV-2 Nsp13 Helicase and Biologically Active Factors

Biochemistry Second Award

Human milk satisfies a baby’s every need. By providing essential nutrients and biologically active factors, milk promotes the infant’s growth and development. Milk also safeguards the infant…

Identifying Underlying Brain Connections in Pediatric ADHD: A Pathway to Early Diagnosis and Reduced Secondary Effects

Behavioral and Social Sciences Second Award

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition affecting millions worldwide. It's marked by difficulties in attention control and impulse management…

Impact of Toroidal Propeller Design on Unmanned Aerial Vehicle Acoustic Signature and Aerodynamic Performance

Engineering Technology: Statics & Dynamics Second Award

Unmanned aerial vehicles (UAVs) are increasingly used for many applications across a range of industries. Increased UAV usage poses a public health and environmental threat due to the annoyi…

Improving Aerodynamic Characteristics of Helical Wind Turbines With Modified Blades

Energy: Sustainable Materials and Design Second Award

Amidst rising energy prices, electricity use is being reduced in Germany. This necessitates shutting down streetlights, their operation being cost-inefficient for communities. The efficiency…

Integrated Stress Response Activation Discovered to Be the Predominant Response to Mitochondrial Dysfunction: A Therapeutic Target Advancement

Biomedical and Health Sciences Second Award

Our bodies continually encounter genetic and developmental stresses, activating stress-responsive signaling pathways to promote proteostasis. However, when these stresses persist and signali…

Integration of Deep Learning Into Automatic Volumetric Cardiovascular Dissection and Reconstruction in Simulated 3D Space for Medical Practice

Systems Software Second Award

Accurate and efficient analysis of cardiac images is essential for diagnosing and treating cardiovascular disease, a major cause of mortality globally, including Vietnam. However, this task…

Investigating the Effects of Hemarthrosis on the Structure and Function of ACL Repair

Biomedical Engineering Second Award

Anterior cruciate ligament (ACL) injury, which affects nearly 200,000 patients annually in the United States, can be accompanied by joint bleeding but the effects of whole blood components a…

Low-Cost Rapid Response Rocket Launched UAV for Wildfire Hotspot Detection

Engineering Technology: Statics & Dynamics Second Award

The 2023 Canadian wildfire season, marked by a quintupling of damage relative to the past decade’s average and the tragic loss of four firefighters, underscores the urgent need for advanceme…

MiniMesh: Real-Time 5,000-Node Anatomical Human Body Mesh Reconstruction for Portable Devices

Biomedical Engineering Second Award

Human Mesh Recovery is the challenge of predicting thousands of three-dimensional points on the human body surface, supporting critical applications in medicine, augmented reality, animation…

Novel Elastomeric Polystyrene via Photopolymerization and Post-Functionalization of Durable Ultra-High Molecular Weight Perfluorostyrene Copolymer

Chemistry Second Award

The development of durable and sustainable plastics is essential for the advancement of our society. Ultra-high Molecular Weight (UHMW) polymers are highly attractive due to the extreme dura…

Photobiomodulation on In Vivo and In Vitro Wound Models Under Simulated Microgravity for Future Space Travel

Translational Medical Science Second Award

Studies on astronauts in space show that microgravity disrupts the delicate balance of processes required for wound healing, slowing it down or even stopping it completely in space. This pre…