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Variational Autoencoder Latent Space as a Robust Clinical Classification Tool for Neurodegenerative Diseases

Computational Biology and Bioinformatics Second Award

The growing prevalence of neurodegenerative diseases underscores the importance of improved diagnostic accuracy. Many proposed Clinical Decision Support Systems (CDSS) have low interpretabil…

Wearable Stethoscope Array for Cardiopulmonary Sound Localization and Interference Suppression Using Beamforming

Biomedical Engineering Second Award

Traditional auscultation devices and methods have inherent limitations in spatially localizing body sounds and suppressing interference—restricting their diagnostic potential. This project d…

Year II, A Comprehensive Eco-Friendly Strategy for Citrus Greening Disease Management: Targeted Delivery of Novel Multi-Compound Formulation Derived From Murraya koenigii in Combination With Steam Therapy Approach and Its Validation Through Precision Agriculture Tools

Plant Sciences Second Award

Huanglongbing (HLB) or the Citrus Greening Disease (Candidatus Liberibacter asiaticus) is the most destructive citrus disease worldwide. Currently, no pesticide is registered to cure this di…

3D-Printed Hemp-based Artificial Coral Reefs as Biodegradable Solution for Marine Restoration

Earth and Environmental Sciences Second Award

As the third largest coral barrier reef system in the world, the Florida Keys is home to thousands of marine life species and faces a myriad of threats resulting in a 90% decline in healthy…

A Comparison of Machine Learning Models (CNN and SVM) in the Novel Supervised Image Classification Approach for the Accessible Diagnosis of Alzheimer's Disease via Clock Drawing Tests on Mobile Phone Applications

Translational Medical Science Second Award

Elderly populations are at an increasing risk of dementia, and accessibility to status-quo diagnosis tools is a significant issue, as proposed by the substantial rates of undiagnosed cases.…

Aerosol Driven Purification: A Novel Method for Purifying Water Utilizing Phase Changes

Environmental Engineering Second Award

Industrial Reverse Osmosis (“RO”) provides safe drinking water to homes and is supplied by ocean water. As such, the quantity of waste water produced by this method is inconsequential. Notab…

AI-Powered Magnetic Inspection Robot for Advanced Structural Health Monitoring of Ferromagnetic Structures

Engineering Technology: Statics & Dynamics Second Award

Over 130,000 aging steel bridges in the United States are at risk from corrosion and structural issues. More efficient and thorough inspection methods are necessary to avoid future disasters…

A Low Cost and High Performance Xylem-Activated Carbon Filter Water Purification Device: A Novel Approach to the Global Clean Water Crises

Environmental Engineering Second Award

Globally, over 2 billion people lack access to safe drinking water leading to 3.4 million waterborne deaths yearly. Existing purification methods are often ineffective against both biologica…

An Elementary Method for Fast Modular Exponentiation With Factored Modulus

Mathematics Second Award

The rise of modern cryptosystems introduced the problem of modular exponentiation. Modular exponentiation is the problem of computing a perfect power a^n modulo some modulus, say m. This pro…

An Integrated Algae Mitigation System to Seek & Abate Harmful Algal Blooms (Year 5)

Environmental Engineering Second Award

Surges in Harmful Algal Blooms (HABs) due to fallouts of anthropogenic activities and climate change are recurrently impairing water quality. Biodiverse ecosystems like the Indian River Lago…

A Novel Duckweed Cultivation Method to Maximize Its Nutritional Value for Future Sustainable Food Development

Plant Sciences Second Award

A child dies from hunger every 10 seconds due to the rising global crisis in food accessibility, security, and sustainability. Therefore, the need for a sustainable food source is becoming m…

Applying Magnetic Fields and Lewis Acids for a Highly Efficient and Cost-Effective Hydrogen Production From Seawater

Energy: Sustainable Materials and Design Second Award

Green hydrogen is a renewable fuel and is considered one of the most promising alternatives to fossil fuels; however, commercialized production is hampered due to the high production cost an…

ArabLexify: Elevating Early Dyslexia Diagnosis in Arabic-Speaking Children Ages 6-12 by Utilizing Accessible Digital Screening Tool

Behavioral and Social Sciences Second Award

Dyslexia, a neurodevelopmental disorder affecting up to 20% of the global population, presents unique challenges for Arabic speakers due to the language's distinctive properties. The scarcit…

A Single Case Pilot Study of an AI-driven Speech Therapy Game for Children with Articulation Challenges Using a Smart Bracelet

Cognitive Science Second Award

AuralStudio: A Multisensory Development Environment With a Novel, Bytecode-Compiled Programming Language

Systems Software Second Award

According to the World Health Organization, nearly 300 million people worldwide suffer from visual impairments, a number which is only expected to grow in the coming years. In the U.S. alone…

Autophagy in Non-Cell Autonomous Regulation of Adipogenesis

Cellular and Molecular Biology Second Award

Age-related metabolic disorders often result from the dysfunction in adipose tissue, which is responsible for energy storage and mobilization. Formation of the adipose tissue or adipogenesis…

Balancing Misclassification Costs (BMC) in Imbalanced Classification

Mathematics Second Award

Classification tasks in machine learning, essential for applications ranging from fraud detection to medical diagnoses, frequently encounter the challenge of imbalanced datasets. These imbal…

Bee's Spa: An Artificial Mud Puddle for Highland Beekeeping to Reduce Bee Mortality During Drought Stress

Animal Sciences Second Award

Drought stress, one of the most critical factors affecting leading to the decline of honey bee (Apis mellifera) populations worldwide, is regarded as a potential threat to species extinction…

Biofilm Composition in Fungi Fusarium and Development of a Multi-targeted Antifungal Treatment To Inhibit Proliferation

Microbiology Second Award

Fusarium is a genus of fungi that produces biofilms, a collection of microbial cells that confer high antifungal resistance to opportunistic Fusarium pathogens, which cause lethal infections…

Bio-Inspired Wing Design, Aerodynamic Simulations, and Autonomous Flight Tests for Airborne Wind Energy

Energy: Sustainable Materials and Design Second Award

Airborne Wind Energy (AWE) poses uncertainty in its contribution to renewable energy due to the lack of a comprehensive design . The technology is in its early stages, requiring significant…

Bursting Bubble Ice

Earth & Environment: Air/ Water Second Award

CABMS: The First System Against California Marine Biotoxins Through Deep, Spatiotemporal, Multivariate Prediction and Sensor-Based Data Transmission

Earth and Environmental Sciences Second Award

To combat marine biotoxin contamination that threatens California’s $15-million shellfish industry, this research establishes the first California Marine Biotoxin Management System (CABMS),…

CardioNet: Synthesis of a Diagnostic-Caliber 12-Lead Electrocardiogram Using Generative Neural Networks and Novel Feature Extraction Techniques

Robotics and Intelligent Machines Second Award

Cardiovascular disease (CVD) is the leading cause of death in the United States. However, early detection can prevent up to 80% of associated fatalities. 12-lead Electrocardiograms (ECGs) ar…

Characterizing a Novel Flare in the Distant Quasar VIIIZw233

Physics and Astronomy Second Award

Every second in the universe an exciting event is occurring, whether it be the collision of two black holes or the death of a star in an explosive supernova. One such event is a Tidal Disrup…

Chromoplexy Rearrangements: Investigating the Functional and Diagnostic Role of Novel Mutational Mechanisms Uncovered In Cancer Genomes

Computational Biology and Bioinformatics Second Award

Conventionally, tumorigenesis is understood as a gradual accumulation of genetic mutations. Yet, chromoplexy rearrangements (ChRs) are a mutational phenomenon characterized by highly complex…

Constructing A Concussion Detecting Headband that Alerts a Concussion Based On Force of Impact

Applied Mechanics & Structures Second Award

Deep Learning on a Novel Ising Model To Study Arctic Sea Ice Dynamics

Physics and Astronomy Second Award

The centennial Ising model, which was initially proposed to explain ferromagnetism and phase transitions, has become a central pillar of statistical physics and a powerful tool in diverse ap…

De Novo Drug Design as GPT Language Modeling: Large Chemistry Models With Supervised and Reinforcement Learning

Computational Biology and Bioinformatics Second Award

In recent years, generative machine learning algorithms have been successful in designing innovative drug-like molecules. SMILES is a sequence-like language used in most effective drug desig…

Design of a Low-Cost, Low Inertia, Backdrivable Upper-Body Humanoid

Robotics and Intelligent Machines Second Award

General purpose humanoid robots have long been envisioned for a plethora of applications such as disaster relief, industrial automation, agriculture, or elderly assistance. A humanoid form f…

Design, Synthesis, and Testing of Novel Small Molecule Interleukin-6 Inhibitors for the Amelioration of Inflammatory Bowel Disease

Translational Medical Science Second Award

Inflammatory Bowel Disease (IBD) is a prevalent autoimmune condition that affects 2.39 million Americans and is characterized by an excess of inflammatory cytokines. Interleukins, a class of…