Software Design
Second Award
This project addressed a critical gap in adolescent mental health support by expanding TheraBee, an artificial intelligence-powered screening and support-routing application for teenagers. T…
Behavioral & Social Sciences (Junior Division)
Second Award
The way information is expressed plays a role in the feelings it elicits. Because general language represents broad concepts and specific language narrows claims, I hypothesized that, in pol…
Cellular and Molecular Biology
Second Award
Drug combination therapy is a cornerstone of modern oncology, but identifying effective combinations for a patient's specific tumor remains difficult as possible combinations grow rapidly wi…
Energy: Sustainable Materials and Design
Second Award
All-solid-state lithium-sulfur batteries (ASSLSBs) have emerged as the next-generation energy storage systems due to their high energy density (~2600 Wh kg?¹) and safety, enabled by non-flam…
Biomedical Engineering
Second Award
The human brain is the most complex object in the universe, with over 86 billion neurons, each containing ~10,000 synapses. Determining the structure of the human brain in its entirety can p…
Zoology (Senior Division)
Second Award
Polycyclic aromatic hydrocarbons (PAHs) such as phenanthrene are widespread marine pollutants known to disrupt developmental and physiological processes in organisms, yet their molecular eff…
Environmental Engineering
Second Award
Lithium is essential for rechargeable batteries, and demand is rising rapidly due to E-mobility and clean energy growth. About 66% of the world's lithium is produced through brine pond evapo…
Environmental Engineering (Track 2) (Junior Division)
Second Award
Throughout the world coral reefs are dying out due to changes in water temperature and pollution, ruining one of the most important ecosystems in terms of food, resources, and products for h…
Translational Medical Science
Second Award
Melanoma is the most fatal type of skin cancer, taking over 50,000 lives annually. While advances in checkpoint immunotherapy have decreased mortality rates, it is difficult to determine whi…
Mathematics
Second Award
Cryptographic systems securing global communications depend on computationally hard mathematical problems. Yet, the divisibility structure of combinatorial objects like Pascal’s Triangle rem…
Physics & Astronomy (Senior Division)
Second Award
The computational power of quantum computing is expected to expedite advances in fields from chemistry to machine learning. However, this potential is locked behind the high error rates of p…
Chemistry
Second Award
Silicon (Si) anodes could revolutionize lithium-ion batteries by expanding capacity eleven-fold. However, Si expansion during charging compromises battery integrity, preventing practical app…
Mathematical Sciences (Junior Division)
Second Award
VisionSpeak: A Wearable Edge-AI System That Describes the World Through Synthesized Speech for the Visually Impaired Shreyan Biswas Our project aims to enhance independent mobility and safet…
Earth & Environmental Sciences (Junior Division)
Second Award
Microfiber pollution from household laundry is a significant environmental concern. Synthetic textiles release microscopic plastic fibers during washing that enter aquatic and terrestrial ec…
Energy: Sustainable Materials and Design
Second Award
The growing need for an efficient small-scale wind energy system led to the investigation of a biomimetic combination of hammerhead shark-inspired tubercles and golf ball dimple surface roug…
Medicine & Physiology (Track 2) (Senior Division)
Second Award
Can neuron resilience be predicted as a topological failure of cellular identity? Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease marked by TDP-43 aggregation and mo…
Plant Sciences
Second Award
The fall armyworm is a destructive pest affecting more than 80 plant species, most notably maize, resulting in an estimated $9.4 billion in annual agricultural losses. As the global populati…
Physics and Astronomy
Second Award
Neutrino oscillation measurements aim to find fundamental physics beyond the Standard Model, but precision is limited by our inability to distinguish genuine signals from interfering nuclear…
Engineering Technology: Statics & Dynamics
Second Award
This project introduces a fully self-designed, completely open-source, and affordable rocket module aimed at addressing real-life challenges that cannot be effectively solved by existing tec…
Chemistry
Second Award
Organic pollutants, such as synthetic dyes and petroleum-based contaminants, pose ecological risks due to their chemical stability and resistance to biodegradation. Nanotechnology offers sol…
Computational Biology and Bioinformatics
Second Award
This research expands existing Olfactory Receptor (OR) studies, exploring their potential in cancer drug therapy and establishing a novel pipeline applicable to similar G protein-coupled rec…
Embedded Systems
Second Award
The most significant weakness and vulnerability in the wildfire response chain lies in the early detection/reaction phase. The physics of wildfire growth are exponential. Any reduction in re…
Materials Science
Second Award
Chitosan, derived from chitin in crustacean shells, is one of the most abundant biopolymers found on the earth. It is important for biomedical material drug delivery and hydrogels. It has an…
Environmental Engineering
Second Award
Estuaries are vital breeding grounds for species of flora and fauna, supporting resources for coastal communities worldwide. However, the ecosystem is rapidly declining due to eutrophication…
Behavioral and Social Sciences
Second Award
Deepfakes are a rapidly improving tool for disinformation. In 2025, around 8 million deepfakes were shared online, with numbers doubling every 6 months. Research has found that people strugg…
Translational Medical Science
Second Award
Alzheimer's disease (AD) remains difficult to diagnose in its early stages. Current diagnostic approaches often miss subtle early symptoms, delaying intervention. In this research, a novel m…
Energy: Sustainable Materials and Design
Second Award
Thirty-five million Americans have an implanted medical device (IMD), like a pacemaker. IMDs have a fixed battery life (~7-12 years), requiring invasive surgery to replace the battery, with…
Cellular and Molecular Biology
Second Award
Neurodegenerative diseases (NDDs), like Alzheimer's and Parkinson's, are characterized by impairment of synaptic plasticity, the brain's capacity to rewire connections critical for cognition…
Biomedical and Health Sciences
Second Award
Each year, over 10,000,000 people lose their lives to cancer. Many current cancer therapies cause deleterious side effects for patients and have an inordinate cost, ultimately leading to pat…
Animal Sciences
Second Award
This study aims to enhance blue swimming crab larval survival for conservation before release into natural habitats, reducing environmental impact. Blue swimming crabs (Portunus pelagicus) p…