Fourth Award
Diabetes mellitus currently affects over 346 million people worldwide and is one of the leading causes of death. Current treatment requires frequent blood-glucose tests followed by necessary…
Fourth Award
Bacterial cells can have DNA damage due to transcriptional error, or through the effect of an antibiotic. The SOS response is a bacterial cell program for coping with DNA damage, in which th…
Fourth Award
Bacteriophages have been known to be capable of eliminating deadly bacterial infections, but their use on biofilms in medical settings has been very limited. In this proof-of-principle inves…
Fourth Award
Melanoma is the most dangerous type of skin cancer and its incidence has significantly increased in the past decade. Inherited mutations in CDKN2A, which encodes the p16 tumor suppressor, pr…
Fourth Award
The purpose of this experiment was to create and test a computer model to accurately and automatically classify cardiac arrhythmias. Such a model, in the absence of trained cardiac professio…
Fourth Award
Our objective is to offer internal communication everywhere the organization needs it, with the possibility to grow to external communications, taking advantages of pre-existing infrastructu…
Fourth Award
The bacterium Enterococcus faecalis is a common source of hospital acquired infections due to its intrinsic resistance to cephalosporins. As antibiotics become less effective at preventing a…
Fourth Award
Osteoarthritis (OA) is a debilitating disorder affecting over 27 million adults in the United States; with the knee being the most commonly affected joint. During OA progression the articula…
Fourth Award
Eutrophication is a severe type of water pollution from excess nutrient inputs (NO3 and PO4). Many nations cannot maintain its expensive chemical treatments. Lemniodeae, a macrophyte known a…
Biomedical Engineering
Fourth Award
Autosomal-dominant Retinitis Pigmentosa (adRP) is caused by diverse gain-of-function mutations in rhodopsin (RHO). The purpose of this study is to aid in the development of a mutation-indepe…
Fourth Award
Surgical site infections, SSI’s, are the leading type of infection in countries with limited resources, affecting up to 2/3 of operated patients with a frequency up to nine times higher than…
Fourth Award
Schizophrenia is a mental disorder that affects the essence of what makes people human. It drastically alters a person's perception and actions until the patient becomes harmful to oneself o…
Fourth Award
Recently a new emphasis has been placed on protection headgear in hockey and other sports as the importance concussion and sub-concussive brain Injury has been better understood, A Summation…
Fourth Award
The purpose of my project was to attempt to create a device which would make invasive surgery less intrusive by removing the need for much of the physical dissection. I planned to accomplish…
Translational Medical Science
Fourth Award
Nuclear actin, while still poorly understood, plays a role in DNA replication, chromatin organization, and gene expression. This research uses Drosophila oogenesis as a model to study in viv…
Translational Medical Science
Fourth Award
Piezo proteins have been identified as key components of mechanosensitive ion channels in humans and other mammals. These channels are in the early stages of characterization; their mechanis…
Fourth Award
Everybody knows that cleaning the oral cavity is good for oral hygiene. However, not everyone knows that during the night sleep, when our mouth doesn’t do saliva flushing, bacteria grows a l…
Fourth Award
The age of robotics is upon us as we blast through the 21st century, our technology continues to increase exponentially. Rapid advancements in 3D printing is revolutionizing the world of eng…
Fourth Award
Parkinson’s disease (PD) is a chronic central nervous system degenerative disease associated with resting tremor, bradykinesia, rigidity, and progressive degeneration of dopaminergic neurons…
Energy: Sustainable Materials and Design
Fourth Award
Improper signaling of the nuclear factor-?B (NF-?B) pathway plays a critical role in many inflammatory disease states, including cancer, stroke, and viral infections. Although a majority of…
Translational Medical Science
Fourth Award
Atherosclerosis, a form of cardiovascular disease, accounts for 17.3 million deaths/year(Mozaffarian,2014). Characterized by plaque formation in arteries, it leads to myocardial infarctions…
Fourth Award
Cellulose synthase (CESA) complexes, which are essential for cellulose biosynthesis, are bridged to cortical microtubules that enable them to reach the cell wall by the CESA interactive prot…
Fourth Award
Nematodes cause significant economic losses in crop production throughout the world and can cause illness in humans and other mammals. The purpose of this study was to determine potential ef…
Energy: Sustainable Materials and Design
Fourth Award
Demand for non-addictive, tissue-specific pain relief has been growing ever since the IOM confirmed that pain afflicts more Americans than cancer, heart disease, and diabetes combined. In ye…
Fourth Award
A novel nano-oligosaccharide doped graphene sand composite filter (NOGOS) was created to serve as a simple, economical, and effective water filter in developing countries, where fresh water…
Fourth Award
Preliminary research has shown that certain natural substances can be used without the fear of a new resistant strain developing. Thus, this project aims to determine the effectiveness of na…
Fourth Award
The main purpose of this project is to further improve the models available for calculating the energy output of tidal barrages. This project will build on the previous year's project, which…
Translational Medical Science
Fourth Award
Cancer cells metabolize some basic nutrients, such as glucose, differently than normal cells do. Recently, investigation on cancer metabolism has increased due to the discovery of new metabo…
Fourth Award
The United Nations estimates that 2.5 billion people worldwide are living without access to clean water with over 2 million dying each year from waterborne disease. Continual exposure to unc…
Fourth Award
There is no curative therapy for liver cancer, the second leading cancer mortality worldwide, therefore cancer chemoprevention is the most impactful strategy to improve the dismal prognosis.…