Year 2 Study - EcoPatch: Innovative Biodegradable Band -aids to Assess the Efficacy of Quercetin and Amoxicillin in Wound Care Application

Overview

Band-aids are used to speed up the healing process and protect wounds from germs. Certain studies have revealed that commercial bandages may not be as efficient as what is advertised. Annually, over 200 million units of bandages are sold in the United States alone. Because of this, countless bandages are being discarded, leading to significant increases in landfill waste. To address this problem, this study investigated a possible alternative to commercial band-aids using Quercetin and Amoxicillin. This experiment was accomplished using the following methods: First, to prepare the concentrations, I designed 15 formulations from A -Owith varying concentrations. Secondly, I heated the materials using a hot plate and magnetic stirrer to encapsulate the formulation. Thirdly, the Kirby -Bauer Assay was conducted to test their antimicrobial effects. Band -aid A with no concentration was used as a control. To create the biodegradable band-aid, 1 gram of agar-agar, sodium alginate and carboxymethyl cellulose, w ere mixed and heated in 100ml distilled water, vinegar and glycerin. Heated solutions were placed in a mold and let to rest at room temperature. Lastly, antimicrobial assays (Kirby -Bauer and Area Coverage Analysis) were conducted. All the data was analyzed using Bliss Synergy, Chuo Talalay, and Microsoft excel. The results showed that the formulation with higher concentrations has higher zones of inhibition. This was supported by the calculated p -values of less than 0.05. Among all the formulations, J and Kshowed effectiveness when combined. The biodegradable band-aid infused with Quercetin and Amoxicillin demonstrated great antimicrobial effects against E. coli.

Competition history

• JSHS 2025 Category not listed

Resources

• National JSHS abstract book ↗

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