Wearable Electrochemical Sweat Sensor for Patients with Chronic Kidney Disease, Year II
ISEF · 2021 Biomedical Engineering
Overview
Chronic kidney disease (CKD) hinders the ability of kidneys to filter the blood effectively and in most cases result in renal failure that forces patients to depend on a blood dialysis machine at scheduled appointments to filter their blood for the rest of their life. This project aims to mitigate this problem by designing an at-home, point-of-care, wearable biosensor that can detect the level of urea from sweat. This will help determine how often patients need to get their blood filtered, saving time and money. Previous scientific literature suggests that the level of urea in sweat is directly correlated to that of urea in blood. For this project, an electrochemical sweat sensor was created utilizing an Arduino microcontroller that determines the voltage created when urease enzyme is added to a solution with known concentration of urea. This voltage produced is said to be directly proportional to the amount of urea. The hypothesis is that there will be a direct relationship between the voltage produced concentration of urea in the solution. It is also hypothesized that the relationship will be independent of volume such that miniaturization will be possible. Varying concentrations of urea were used (0.2M-1.0M). The Arduino voltmeter was used to determine the relationship, if any, of the voltage created and the concentration of urea. 15 readings were taken for each concentration at 10mL, 50mL, and 100mL of solution. The result of the experiment suggests that there is a direct relationship between concentration of urea and voltage produced that is independent of volume, such that miniaturization is possible in future experiments.
Competition history
- ISEF 2021
Resources
Related projects
ISEF · 2022
Wearable Electrochemical Sweat Sensor for Patients With Chronic Kidney Disease (CKD): Year III
CWSF · 2026
NephroSense: Developing a Chronic Kidney Disease Screening Model for AI Breath Biomarker Testing
ISEF · 2020
Edge- Intelligence Biosensor Based Point-of-Care Diagnostic Device for Chronic Kidney Disease
ISEF · 2020
Novel Method of Monitoring Chronic Kidney and Other Renal Diseases using Colorimetric Test Strip Sensor and IoT Enhancement
Closest projects by meaning, across every fair and year in the corpus.
Source: Regeneron International Science and Engineering Fair