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The Use of Alloplastic Implants as Antibiotic Delivery Devices in Facial Reconstructive Surgery

CSEF · 2005 Microbiology

Morgan S. Keefe · Warren Walker School, San Diego

Overview

Objectives/Goals The objective of this project was to determine whether alloplastic implants can be used to deliver antibiotics to the site of implantation during facial reconstructive surgery. Methods/Materials Using controls and an identified bacterial population plated on Mueller Hinton Agar, I tested the variables of time and type of immersion of the implant in antibiotic with regards to the effectiveness of bacterial killing for the alloplasts e-ptfe and Phdpe. Results Negative pressure infultration of the implants showed a highly significant bacterial killing over the controls. Conclusions/Discussion Alloplastic implants bieng used in surgical reconstruction can be used to deliver antibiotics to an implant site, which can subsequently decrease the risk of infesction.

Summary statement

Determining if alloplastic implants can be used to potentially deliver antibiotics to a surgical implant site. (in-vitro)

Help received

Captain Michael Keefe helped with protocol design; Microbiology Laboratory at Naval Medical Center San Diego helped with materials and design of culture technique; Dr. Derrin Wester helped with statistical analysis; Captain Kelly S. Keefe helped with board design.

Awards (1)

  • Category Award

Competition history

  • CSEF 2005 Microbiology · Entry J1317

Resources

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