Puzzle of Alzheimer's

I think the problem is that small life style factors in a persons life could cause major changes in their brain which lead to problems like Alzheimer's disease which is irreversable so it important to focus on it in our early /aroud the age of 40 and above . Not many people are aware of how some small changes can prevent allzheimer's .

Background research - General all about alzheimer’s . Find all the 5’A and 5 why . with the question what formed plaques and tangles .

Question - How does Alzheimer's affect the brain ?

Variables - the manipulated variable , responding variable and controlled variable .

Hypothesis - A infer about what symptoms are caused in what part of the brain due to what reason .

Result - Factor’s table

Report - The report of all doctors and the symptoms .

Conclusions - The answer to my question .

What triggers Alzheimer’s?

The causes of Alzheimer’s include the following:

• Age-related changes in the brain (Data: In 2022, nearly 10.7% of Americans aged 65 and over (approximately 6.5 million) were living with Alzheimer’s)

• Genetic Factors - Parent/ Siblings with AD and APOE-e4 gene variant increases the risk

• Lifestyle and Environmental Factors - Cardiovascular Health, Smoking, Alcohol, Poor Diet, Lack of exercise, Sleep problems, Lack of Mental and Social Engagement, Chronic stress, Inflammation

• Brain changes and Protein build up - Amyloid Plaques and Tau plays an important role

Amyloid Plaques: Clumps of beta-amyloid protein that accumulate between nerve cells, disrupting communication.

There are 10.7% or 6.5 million Americans (65 and over) living with Alzheimer’s in 2022 .

The number of individuals living with Alzheimer’s disease can increase to 13.8 million by 2060.

72.9% (4.72 million) of the total Alzheimer’s cases in the US are people aged 75 and above.

Alzheimer’s disease affects a person's brain in many ways it kills neurons, the brain shrinks due to Alzheimer’s , formation of plaques and tangles,it fades their memory and declines their thinking abilities etc.

Title | Author | Information (web link, publisher, etc) | Year

National Institute on Aging | | Alzheimer's Disease Fact Sheet | National Institute on Aging |

Alzheimer’s Society of Canada | | What is Alzheimer's disease? | Alzheimer Society of Canada |

Mayo clinic | | Alzheimer's disease - Symptoms and causes - Mayo Clinic |

Drbeen medical lecture | | Colorectal Cancer Study with This Amazing Drug |

Alzheimer's association | | Alzheimer's & Dementia Help | Canada | Alzheimer's Association |

| | |

Title | Author | Information (web link, publisher, etc) | Year

Dementia society | | what is alzheimers - Dementia Society |

Seeking alpha | | Alzheimer's Disease: 40 Years In The Wilderness | Seeking Alpha |

Wikipedia | | Alois Alzheimer - Wikipedia |

U.S News | | Preventing Dementia and Alzheimer’s: 8 Habits to Reduce Your Risk | U.S. News |

CFAH | | Alzheimer’s Disease Statistics & Facts (2023 Update) |

Alzheimer’s | | Alzheimer's disease - NHS |

I would like to thank my Ms.Olfert , Ms . Kim as well as some of my teachers .