How Dietary Restriction Affects the Athleticism, Metabolic Rate, and Lifespan of Drosophilia melanogaster

Overview

Obesity is a notable health risk factor that increases morbidity and mortality. Some factors that contribute to obesity are lifestyle choices including excessive eating habits, low exercise routines, and genetic factors. Although it is perceived that persons at an unhealthy weight have increased the risk of many metabolic disorders, it does not confirm that they will develop obesity-related illnesses. Dietary restriction (DR) is the limiting of total food intake without causing malnutrition. A common dietary restriction with strong benefits against obesity is a low-protein, high carbohydrate diet, which has gained popularity due to its ability to slow obesity symptoms in a timeframe of 48 hours as shown in studies with Drosophila melanogaster. Past studies have shown that fly strains, such as bmm1, and DR can increase the lifespan of obese fruit flies. This study is the first to test the idea by comparing a normal diet with DR of male and female bmm1 and chico virgin flies in a series of geotaxis, respirometry, and lifespan assays. Results showed that DR increases lifespan but not metabolic rate and athleticism. It also showed that bmm1 flies had lesser symptoms compared to chico. No statistical difference was seen between males and females. By investigating potential beneficial dieting techniques, obesity conditions can be improved leading to better treatment options for individuals to live healthier lives.

Competition history

• JSHS 2022 Category not listed

Resources

• National JSHS abstract book ↗

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