Fast MRI: Reconstructing MR Images Using Undersampled k-space and a GAN

Overview

Magnetic Resonance Imaging (MRI) is used extensively across the world to get detailed physiological images that are unattainable with other imaging modalities. Although it has widespread appeal, the MRI process tends to be noisy, confined, and can cause discomfort when a patient is being scanned. In addition, the patient needs to be completely still during the scan to ensure the machine can acquire a good image, a significant issue for seniors and children. My project aims to address these problems by reconstructing MR images via under-sampling the underlying data of the MR image, which is called k-space. A generative adversarial network (GAN) was constructed, and consisted of two separate neural networks, a generator network that generated samples of an image, and a discriminator network which compared the generated sample to a ground truth version of that image. I used public datasets (OASIS3 and IXI) and preprocessed each image with Fourier transforms, line-by-line sampling, and normalization. Multiple iterations of the generator model were attempted over 500 hours of training before the final U-Net inspired model trained on a Tesla V100 GPU for 100 epochs. The generator was able to successfully generate images similar to the ground truth MRI images in the testing dataset, with a true positive to false positive ratio (AUC-ROC) for the discriminator of 0.58 (a perfect generator would have AUC-ROC of 0.50). The contributions of this project include reducing the costs of MRI, reducing the discomfort and error of the process, and increasing the speed of the process.

Awards (2)

• Third Award of $1,000 $1,000
• Mu Alpha Theta, National High School and Two-Year College Mathematics Honor Society: Second Award of $1,000 $1,000

Competition history

• ISEF 2019 Robotics and Intelligent Machines · Entry ROBO006

Resources

• ISEF abstract page ↗

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