Bio-Ink: Investigating the Mechanical Potential of Protein for 3D Bioprinting

Overview

Three-dimensional (3D) bioprinting conventionally involves additive manufacturing of carbohydrate-based materials such as hydrogel and cellulose. These materials, often referred to as bio-inks or biomaterials, must meet certain mechanical and biological properties before, during, and after extrusion. As 3D bioprinting is still a nascent field, limitations exist to the range of biomaterials available and appropriate for bioprinting. Advancements in this field would allow bioprinting to be established as a stable source of artificial organs that could meet the ever increasing demands of organ transplants. In this research, we evaluate two types of protein, bovine vitreous humor and chicken albumin, as potential biomaterials by investigating their pre-bioprinting mechanical properties, especially viscosity. Furthermore, we develop and improve prototypes that mimic the 3D bioprinting process to evaluate the potential of chicken albumin as a biomaterial. Furthermore, we design specific tests for the prototypes to perform and evaluate them based on set criteria, including print speed, resolution, and ability to solidify the bio-ink for structural integrity post-extrusion.

Competition history

• AJAS 2019 Category not listed

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