Translational Medical Science
The obesity pandemic affects 36.5% of the US adult population and exacerbates the risk for deadly comorbidities including Type II Diabetes (T2DM). Current obesity and T2DM therapeutics are n…
Biomedical Engineering
Propofol is the most common anesthetic agent used in the United States, but 60% of the time patients feel pain on injection (Jalota et al. 2011). This pain is hypothesized to be from the fre…
Cellular and Molecular Biology
FACT is a complex of 2 subunits: SSRP1 and SPT16. Both subunits are required to be present and associated with each other through their dimerization domain (DD) in order for FACT functionali…
Biomedical and Health Sciences
Third Award
MicroRNAs (miRNAs) are small non-coding RNAs that can regulate circadian gene expression. This study investigates the relationship of miRNA and microbiome levels to diurnal variations in hum…
Mathematics
Second Award
In this project, Ricci flow and normalized Ricci flow were studied in a discrete 3-dimensional setting, where the manifold of interest is the boundary of a 4-simplex. This manifold is the di…
Behavioral and Social Sciences
Previous literature has indicated that the goals that parents have for their children often become the goals the children have for themselves, and these goals influence certain character tra…
Behavioral and Social Sciences
Third Award
According to Adams and Galinsky’s (2012) enclothed cognition effect, clothing can have a strong influence on an individual's performance. Particular articles of clothing, such as a doctor’s…
Cellular and Molecular Biology
The RE-1 Silencing Transcription Factor (REST) is a central transcriptional repressor that regulates a wide range of neural genes. REST is highly conserved among vertebrates and modulates pr…
Biomedical and Health Sciences
Lacrosse is one of the fastest growing sports in North America, and the physical nature of the sport puts players at risk of sustaining head injuries, including concussions. Concussions are…
Physics and Astronomy
The limitations of four prominent exoplanet detection methods-direct imaging, radial velocity, transit, and gravitational microlensing-were analyzed. It was hypothesized that ranges of descr…
Physics and Astronomy
Third Award
The E821 experiment conducted in the national light source synchrotron in 2001 measured the muon's anomalous magnetic moment to a precision of 0.74 ppm, producing a three sigma difference be…
Robotics and Intelligent Machines
Robots are used in various ways to assist the elderly and handicapped. Since the elderly and disabled often have issues with mobility and manual dexterity, they are more likely to select the…
Materials Science
Most modern electronics utilize silicon semiconducting devices, however limitations in silicon are causing performance in computers to plateau, researchers are looking to new materials to re…
Biomedical and Health Sciences
Third Award
Hepatocellular Carcinoma (HCC) is the second leading cause of cancer death worldwide, and cirrhosis underlies 80-90% of HCC. Cirrhosis is initiated and advanced due to the activation of hepa…
Cellular and Molecular Biology
Fourth Award
The T-box transcription factor TBX3 is highly expressed within the lung endothelium, yet the effect of its expression is unknown. This study aimed to overcome present limitations by determin…
Microbiology
Bacteria are rarely found alone in natural environments. Instead, they are usually located within complex structures composed of extracellular matrices called biofilms. Many species of bacte…
Cellular and Molecular Biology
Fourth Award
Squamous cell carcinoma (SCC) is an invasive type of skin cancer that lacks expression of lecithin-retinol acyl transferase (LRAT), a protein implicated in wound healing and cancer progressi…
Engineering Mechanics
First Award
Despite industrialization, Sub-Saharan Africa’s water infrastructure leaves ~341 million people without access to potable water. In addition to water purification problems, transportation pr…
Behavioral and Social Sciences
Second Award
The phenomenon of lucid dreaming, the state of being aware within a dream, is rare and difficult to control. This study investigates whether multiple awakenings in rapid succession can simul…
Biomedical Engineering
DNA-sequenced engineering of protein nucleants may reduce limitations associated with protein crystallization and structure determination for structure-based drug development. This project i…
Animal Sciences
Imbalances between the inhibitory and excitatory neurotransmitters, gamma aminobutyric acid (GABA) and glutamate, result in hyperexcitability disorders, such as anxiety. Many of these disord…
Behavioral and Social Sciences
Second Award
Maltreatment may arise in various forms, and not every case is as simple as violent behavior from parent to child. The purpose of this visual analysis study was to utilize images and videos…
Earth and Environmental Sciences
Second Award
When excavated 1957-1962, the archaeological site at Isimila, Tanzania, was estimated at 60 ka, from its artefacts’ similarity to other sites, such as Magubike and Kalambo Falls, none of whi…
Systems Software
Effective object tracking is vital to consumer safety and utility in emerging technologies such as self-driving vehicles and automated video tracking. This study centered around the creation…
Plant Sciences
Third Award
Potato late blight caused the Irish Potato Famine and still causes billions of dollars of annual crop damage. Tracking and predicting its spread remains problematic. Growers overspray potato…
Materials Science
Second Award
Multilayered nanoparticles are promising carriers to deliver therapeutic biomolecules across the blood-brain barrier (BBB) for neurodegenerative diseases and traumatic brain injuries. Capabl…
Mathematics
This paper provides a generalization of the Calkin-Wilf tree. The Calkin-Wilf tree is an infinite binary tree in which all nodes are labeled by reduced positive rationals and each reduced po…
Systems Software
Fourth Award
One of the most pressing issues in modern computing is computational speed. In supercomputers, hundreds of thousands of processors, or nodes, are connected in configurations called topologie…
Biomedical and Health Sciences
Musculoskeletal disorders include diverse complications but all suffer from the physiological orthopedic domino effect, namely bone mineral density (BMD) alterations. For instance, increased…
Translational Medical Science
Renal fibrosis, featured by excessive accumulation of extracellular matrix (ECM), is a detrimental path of chronic kidney disease while lacking an effective treatment for 0.5 billion adults…