Physics and Astronomy
The Laser Interferometer Gravitational-Wave Observatory (LIGO) is a ground-based interferometer designed to detect gravitational waves (GWs). The search for these waves in detector data face…
Earth and Environmental Sciences
Approximately 3.5 million people die annually due to inadequate water resources. More than 90% of pollution-related deaths occurred in low-income and middle-income countries. Although resear…
Translational Medical Science
Rheumatoid Arthritis (RA) is an autoimmune arthropathy that affects over 18 million people globally, causing immense joint pain and swelling. Current treatments (e.g., methotrexate, adalimum…
Biomedical Engineering
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, killing about 17.9 million people annually. Most CVDs are age-related, driven by gradual damage to blood vessels, als…
Physics and Astronomy
Hypervelocity stars (HVSs) move on unbound trajectories with extremely high velocities. HVSs are ejected in three-body interactions where binaries are disrupted by a massive black hole's (MB…
Cellular and Molecular Biology
Methylation marks are a type of epigenetic mark established during cellular differentiation that change with time and are often associated with aging and degenerative diseases. Thus, manipul…
Earth and Environmental Sciences
First Award
Nitrous oxide (N2O) is one of the largest contributors to the greenhouse effect (265x more greenhouse forcing than CO2) and is the largest contributor to ozone depletion in the 21st century.…
Earth and Environmental Sciences
Monitoring the global distribution and long-term series changes of the various oceanic carbonate parameters (e.g. pH, total alkalinity (TA), dissolved inorganic carbon (DIC), fugacity of CO2…
Earth and Environmental Sciences
Per- and poly-fluoroalkyl substances (PFAS) are chemical compounds widely used in consumer products and industrial applications, this contamination has ties to severe health risks such as ca…
Systems Software
Second Award
According to the World Health Organization, nearly 300 million people worldwide suffer from visual impairments, a number which is only expected to grow in the coming years. In the U.S. alone…
Translational Medical Science
Second Award
Inflammatory Bowel Disease (IBD) is a prevalent autoimmune condition that affects 2.39 million Americans and is characterized by an excess of inflammatory cytokines. Interleukins, a class of…
Microbiology
Fourth Award
Small Intestinal Bacterial Overgrowth (SIBO) is a poorly understood disease that is characterized by the overgrowth of bacteria in the small intestine. Our current and most researched treatm…
Systems Software
Third Award
Machine Learning (ML) optimizers are widely used to optimize the weights and biases of deep neural networks. However, current methods can suffer from issues like slow convergence and getting…
Earth and Environmental Sciences
Second Award
Oil spills continue to affect millions of families yearly. Significant research has gone into the development of both organic and inorganic solvents. However, the issue with these sorbents i…
Mathematics
Third Award
The cryptocurrency Ethereum utilizes zero-knowledge rollups (ZKR) to improve its scalability. ZKRs processes thousands of Ethereum transactions in a batch and uses zk-SNARKs (zero-knowledge…
Energy: Sustainable Materials and Design
With environmental disasters affecting poorer, disadvantaged communities in disproportionate amounts, solutions that are accessible (i.e. low-cost and abundant resources) are important for t…
Translational Medical Science
In healthy human cells, telomeres are end caps on DNA strands to protect against degradation. However, as cell replication increases, telomeres progressively shorten, eventually triggering c…
Systems Software
Fourth Award
The goal of this study was to create an enhanced yet accessible system to generate simplified summaries of governmental policies, thus enhancing public understanding and mitigating informati…
Chemistry
Per- and polyfluoroalkyl substances (PFAS) are emerging water contaminants of concern due to their toxicity and persistence in the environment. Zeolite nano resins (ZNR) are a promising new…
Chemistry
Fourth Award
In recent years, single-junction perovskite solar cells with lead-halide frameworks have garnered considerable interest for their superior photovoltaic performance, facile fabrication, and t…
Biomedical and Health Sciences
Second Award
1 in 5 people develop cancer in their lifetime. Due to treatment inefficiency, cancer is the leading cause of death worldwide. Deciphering immune cell-cancer cell interactions within the tum…
Physics and Astronomy
Since the Kepler Space Telescope entered service in 2009, the data on exoplanets has increased significantly. Astronomers must manually analyze this data to identify which objects of interes…
Biomedical Engineering
Third Award
Cardiovascular surgery is a complex and high-risk procedure that requires precise navigation to ensure the success of the operation. In recent years, there has been growing interest in the d…
Environmental Engineering
During many industrial fires, the chemicals released from the incineration of materials inside the building and ones commonly used by firefighters to extinguish the fire are often picked up…
Translational Medical Science
In-cell click-formed proteolysis targeting chimera molecules (CLIPTACs) were developed to allow both the inhibition and ubiquitination (degradation) of mutated proteins causing various disea…
Biochemistry
Fourth Award
Standard treatments for gliomas, such as surgery, chemotherapy, and radiotherapy, are often ineffective. Research has shown that the enzyme SUV39H1, which is involved in DNA methylation and…
Biomedical and Health Sciences
First Award
422 million adults worldwide have diabetes, and 48% of all juvenile deaths are due to diabetes or diabetes-inflicted diseases; diabetes in low-income families has risen rapidly---up to 21% w…
Mathematics
Third Award
Quantum computing is revolutionizing cryptography, as it will render the classical digital signature schemes such as Bitcoin's ECDSA (Elliptic Curve Digital Signature Algorithm) insecure. Th…
Cellular and Molecular Biology
The current paradigm in genetics states that mutation is random. However, recent studies with Arabidopsis thaliana have shown that the mutation rate and rate of expression of a gene are nega…
Embedded Systems
Being blind can have a significant impact on a person's quality of life since it impairs their ability to navigate the world and participate in activities many once loved. Many people experi…