Behavioral and Social Sciences
Although death of a loved one is not an uncommon event among school-age children, bereavement-related discussions are still perceived as a taboo. This societal stigma can inhibit the grievin…
Biochemistry
Lateral flow immunoassays (LFIAs) are analytical tools used in many areas, especially in point-of-care diagnostics, and are best known as pregnancy tests and COVID-19 antigen tests. Conventi…
Biomedical and Health Sciences
Mutations in the FLT3 receptor, present in approximately one third of patients with acute myeloid leukemia (AML), are associated with an aggressive course of the disease, a high risk of rela…
Biochemistry
The main goal of the project is to develop a functional, inexpensive and easily reproducible method for testing the interactions of gastrointestinal glycoproteins, mucins, with a wide range…
Embedded Systems
Sports trackers are an indispensable tool for effective training; however, their ability to analyze motion dynamics and ergonomic load distribution remains limited. To bridge this gap, we pr…
Cellular and Molecular Biology
Insulin-like growth factor 2 (IGF-2) is a regulatory peptide involved in neuroplasticity, memory consolidation, and neuroprotection in the CNS. Despite the well-documented association betwee…
Chemistry
Peptide cyclization is a common chemical modification of linear peptides, resulting in the formation of cyclized frameworks. Compared to their linear counterparts, cyclic peptides are well k…
Computational Biology and Bioinformatics
Autism Spectrum Disorder (ASD) is a heterogeneous neurological disorder affecting approximately 1 in 100 children today. The diagnosis and treatment of ASD are complex, partly due to its obs…
Behavioral and Social Sciences
Company valuation influences billions in capital allocation across individual and institutional investors. While established methods like discounted cash flow and dividend discount models pr…
Embedded Systems
According to the World Health Organization, about 43 million people are blind worldwide, emphasizing the importance of assistive technologies to combat their everyday challenges. Our project…
Robotics and Intelligent Machines
Purpose: This research aims to bridge the gap between current computer vision models and true 3D perception. Right now AI/Computer vision models are trained on a huge datasets of many object…
Biochemistry
DNA replication is essential for the accurate transmission of genetic information during cell division. The Rothmund-Thomson syndrome helicase (RECQ4) plays a crucial role in replication ini…
Chemistry
Signaling pathways of specific protein kinases are one of the main forms of intercellular communication. The information transfer is based on the chain of activation responses, often initiat…
Computational Biology and Bioinformatics
Fourth Award
The aim of this research is to detect tumor tissue during brain surgery using data preprocessing and machine learning. Brain tumors are the leading cause of cancer-related death in children…
Chemistry
Immunochemical methods are commonly used for the analysis of biological samples not only in diagnostics but also in primary research. Based on the unique reaction between antibody and antige…
Biochemistry
Bioluminescence, the process of production and emission of the visible light by living organisms has a great application potential in variety of fields, from basic research, bioimaging to co…
Biomedical and Health Sciences
Population aging increases the occurrence of chronic heart disease characterized by decrease of cardiomyocyte number and their contractility. The absence of natural heart self-repair mechani…
Engineering Technology: Statics & Dynamics
Quantum computing promises significant advancements in computational speed and efficiency, presenting new opportunities for solving complex scientific problems. This project aims to fully de…
Plant Sciences
Second Award
The flowering of plants is necessary for their further reproduction. Flowering is regulated by hundreds of genes encoding proteins. The goal of my academic work is to find out how AGO bindin…
Cellular and Molecular Biology
RNA has numerous roles in cells and its information is encoded by its sequence, secondary structure and chemical modifications. The least explored RNA modifications are noncanonical 5' RNA c…
Earth and Environmental Sciences
Aleš Janderka Gymnasium Masaryk Square 8, Šumperk, Czech Republic The thesis focuses on Cretaceous macrofossil, microfossil, and ichnofossil specimens from the Štíty Graben. The research cov…
Computational Biology and Bioinformatics
The aim of this work is to create a program capable of simulating the evolution of organisms together with geological processes. For simplicity, I have focused on the evolution of prokaryote…
Biomedical and Health Sciences
Fourth Award
Alzheimer’s disease (AD) is the most common neurodegenerative disorder contributing to 60–80 % of cases of dementia worldwide, with no effective treatment so far. Alongside the amyloid-beta…
Embedded Systems
Third Award
The goal of this project is to provide real-time split times for orienteering competitions. Orienteering races are typically held in diverse natural terrains, such as forests, that make data…
Chemistry
Metabolic engineering offers possibilities of environmental protection using enzymes in biodegradation cascades, which could be used in degrading toxic pollutants from the environment. In th…
Cellular and Molecular Biology
Lead nanoparticles (PbNPs) in industrial areas pose a potential risk to organisms, therefore it is necessary to study the effects of their chronic inhalation. This project aimed to analyze t…
Physics and Astronomy
For the purpose of detecting cosmic ray flux and analyzing its behavior in relationship with latitude, altitude, solar cycle and meteorological conditions I built my own detector. It consist…
Chemistry
Second Award
Silica capillaries have been an integral part of the instrumentation used in many areas of analytical chemistry for decades, especially in analytical separations. In most cases, they are use…
Physics and Astronomy
Most of the modern technologies rely on very tiny objects and, therefore, nanotechnology is currently very burgeoning area of research. A proper measurement of fundamental magnetic and elect…
Chemistry
N-Aryl hydroxamic acids (NAHAs) represent a group of valuable synthetic intermediates. Their N OH modification, by appending good leaving group (LG), triggers intramolecular rearrangement le…