Every Regeneron International Science and Engineering Fair project Fairfolio holds: 17,565 entries across 13 years, with the abstract, category and awards the fair published for each one.
Counts cover every year of this fair and use its own category labels, exactly as the source published them. Each one links to that category's ISEF projects.
17565 projects · showing 2431–2460
ISEF · 2025
Behavioral and Social Sciences
Cognitive decline is common in aging populations, but early screening is critical to slowing its progression. Current screening tools like MoCA and MMSE are limited by their reliance on read…
ISEF · 2025
Plant Sciences
With food insecurity becoming an increasingly important global issue, understanding the impacts of climate change on agricultural yields through yield forecasting is critical to ensure susta…
ISEF · 2025
Computational Biology and Bioinformatics
Lung cancer remains the leading cause of cancer-related mortality, primarily due to its high metastatic potential and the difficulty of early detection. Current clinical approaches rely on a…
ISEF · 2025
Biomedical and Health Sciences
Cancer is the second leading cause of death in the US. Among the various forms of cancer, breast cancer and lung cancer are particularly significant due to their prevalence and impact. Breas…
ISEF · 2025
Biomedical and Health Sciences
Affecting approximately one in every 1000 babies born in the U.S., congenital hydrocephalus (CH) is the abnormal build-up of cerebrospinal fluid (CSF) in the ventricles of the brain. CH resu…
ISEF · 2025
Behavioral and Social Sciences
According to the National Institutes of Health, 1 in 14 children has Developmental Language Disorder (DLD). It interferes with language learning in children, delaying their academic and soci…
ISEF · 2025
Earth and Environmental Sciences
Anthropogenic methane (CH4) emissions cause roughly 700,000 premature deaths annually; moreover, CH4 is difficult to monitor and predict. Existing methods lack the predictive accuracy and re…
ISEF · 2025
Materials Science
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to the degeneration of motor neurons in the spinal cord and brain. Despite research into various causes—su…
ISEF · 2025
Mathematics
This study aimed to develop a theorem that algebraically calculates the maximum number of spheres inscribed within a ring torus and its resulting total volume. A ring torus is a circle with…
ISEF · 2025
Embedded Systems
This study presents a spherical robot driven by a double-pendulum mechanism that shifts its center of gravity for omnidirectional movement. A robust 3D-printed shell and internal actuation s…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Track and Field athletes often have to walk on their spikes to get from place to place, this makes the spikes dull and less efficient. This project is meant to solve this problem, by creatin…
ISEF · 2025
Systems Software
Increased reliance of societal operations on artificial intelligence (AI) image recognition models renders them vulnerable to security risks from adversarial attacks. These attacks manipulat…
ISEF · 2025
Earth and Environmental Sciences
Biodiversity is essential for ecosystem health and stability. Though springtails are widely accepted as decomposers, recent studies suggest they may also be keystone organisms. Since native…
ISEF · 2025
Mathematics
For a polynomial P(x) with integer coefficients and a maximum positive integer root m, we consider the product of its values from x=m+1 to n and denote it as Fp(n). Building up on previous w…
ISEF · 2025
Computational Biology and Bioinformatics
Molecular dynamics (MD) simulations model how proteins change conformation during key processes like folding and substrate binding. However, simulating every atom, as is done in all-atom sim…
ISEF · 2025
Microbiology
Staphylococcus epidermidis is commonly found on the skin and is typically harmless; however, if left untreated, it can lead to infections that may have serious health consequences. The goal…
ISEF · 2025
Physics and Astronomy
Tidal tails form in open clusters due to two-body relaxation and gas expulsion (Kroupa et al., ApJ, 2024). Mapping tidal tail star trajectories provides key insights into understanding open…
ISEF · 2025
Computational Biology and Bioinformatics
Traditional Darwinian models of evolution treat adaptive selection as the primary evolutionary factor for most traits. Although this approach is predictive in many cases, it struggles to exp…
ISEF · 2025
Behavioral and Social Sciences
Parkinson's disease (PD) is a chronic neurodegenerative disorder affecting over 10 million people worldwide. Gait impairments are a key indicator of brain-body dysfunction in PD. However, ea…
ISEF · 2025
Cellular and Molecular Biology
Approximately 5.9% of the global population—over 300 million people—suffer from rare genetic disorders, many of which require AAV-based gene therapy. AAV-B3, an ancestrally derived serotype…
ISEF · 2025
Biomedical Engineering
Irreversible electroporation (IRE) is an innovative technique that disrupts cellular homeostasis, functioning similarly to non-thermal apoptosis. This method enables the selective ablation o…
ISEF · 2025
Plant Sciences
This study explores the pesticidal efficacy of Mikania micrantha (bitter vine, wathupalu) leaf extracts to be used as a freely available and low cost botanical pesticide against Myzus persic…
ISEF · 2025
Computational Biology and Bioinformatics
Over 70 million in the world suffer from stuttering, a speech impairment characterized by involuntary disruptions during normal speech. This can create communication barriers and limiting ac…
ISEF · 2025
Embedded Systems
High resolution absolute rotary encoders are essential to precision applications like tracking telescopes, semiconductor manufacturing, low-tolerance machining, and robotic mechanisms. Howev…
ISEF · 2025
Engineering Technology: Statics & Dynamics
In natural disaster affected areas, communications infrastructure is often disabled. Without communication systems, search and rescue teams are less able to locate victims and coordinate wit…
ISEF · 2025
Biochemistry
Biofuels are vital in combating climate change by offering a low-carbon alternative to fossil fuels, thus reducing greenhouse gas emissions. Efficiently converting waste materials into fuel…
ISEF · 2025
Energy: Sustainable Materials and Design
This study presents an innovative solar cell chip that integrates micro-capacitors and micro-converters directly into the cell architecture to streamline DC-to-AC energy conversion. Traditio…
ISEF · 2025
Environmental Engineering
The alarming rise in solar photovoltaic (PV) waste, particularly non-biodegradable glass, poses a growing environmental concern, with global waste projected to reach 78 million metric tons b…
ISEF · 2025
Energy: Sustainable Materials and Design
The escalating global energy demand necessitates innovative and efficient storage solutions. However, conventional energy storage devices often require external charging, which can be proble…
ISEF · 2025
Plant Sciences
Fertilizers applied to soilless growing substrates in controlled environment agriculture (CEA) often leach nutrients like phosphorus (P), and this leads to environmental pollution. The objec…